Results 191 to 200 of about 43,569 (363)

DON‐Loaded Nanodrug‐T Cell Conjugates With PD‐L1 Blockade for Solid Tumor Therapy

open access: yesAdvanced Science, EarlyView.
This study establishes DON‐loaded T cell‐nanodrug conjugates with PD‐L1 blockade, creating a synergistic system. As a glutamine antagonist, sustained DON release enhances T‐cell endurance and infiltration by promoting memory differentiation and upregulating adhesion and motility genes, while PD‐L1 blockade alleviates immunosuppression and directs T ...
Xin Yang   +13 more
wiley   +1 more source

A New Synthesis of Lead Azide [PDF]

open access: bronze, 1963
Bruno Reitzner, RALPH P. MANNO
openalex   +1 more source

Manganese‐Catalyzed Electrochemical Diazidation of Dehydroalanine Peptides

open access: yesAdvanced Science, EarlyView.
A Mn(II)‐catalyzed electrochemical method achieves site‐selective diazidation of dehydroalanine peptides with NaN₃. This radical relay process tolerates diverse functional groups, delivers high yields, and enables precise peptide modification, offering a powerful tool for bioconjugation and therapeutic development.
Xinwei Hu   +5 more
wiley   +1 more source

CXCL6 Reshapes Lipid Metabolism and Induces Neutrophil Extracellular Trap Formation in Cholangiocarcinoma Progression and Immunotherapy Resistance

open access: yesAdvanced Science, EarlyView.
CXCL6's function in cholangiocarcinoma is underexplored. Here it is discovered that CXCL6 is upregulated in cholangiocarcinoma tissues and promotes proliferation and metastasis of it. CXCL6 functions through the CXCR1/2‐JAK‐STAT/PI3K axis and reshaping tumor lipid metabolism.
Tian He   +15 more
wiley   +1 more source

Synthesis of hypermodified adenosine derivatives as selective adenosine A(3) receptor ligands [PDF]

open access: yes, 2006
Cosyn, Liesbet   +5 more
core   +2 more sources

Low-Frequency Molecular Motions in Ammonium Azide [PDF]

open access: bronze, 1966
Henri Boutin   +2 more
openalex   +1 more source

Functionalized Biomimetic Nanoparticles Targeting the IL‐10/IL‐10Rα/Glycolytic Axis in Synovial Macrophages Alleviate Cartilage Degeneration in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
The MOF material UIO‐66‐NH2 is functionalized with DBCO groups on its surface, encapsulating NO‐prednisolone and conjugating it with azide‐modified IL‐10. Finally, the complex is extruded with MM to form biomimetic functional nanoparticles. Upon intra‐articular injection, MI@UN, enveloped by the MM, specifically targets synovial macrophages, is ...
Wenwei Li   +10 more
wiley   +1 more source

Development of Low Temperature Activatable Aryl Azide Adhesion Promoters as Versatile Surface Modifiers. [PDF]

open access: yesACS Appl Eng Mater
Atzemoglou AA   +5 more
europepmc   +1 more source

Enhancing Stability of Inverted Perovskite Solar Cells via Buried Interface Modification Using In‐Situ Crosslinked Thiol‐Ene Polymer

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
Two crosslinkable molecules are introduced into the buried interface of perovskite to regulate the interfacial contact between [2‐(3,6‐dimethoxy‐9H‐carbazol‐9‐yl)ethyl]phosphonic acid and perovskite. The cross‐linked interfacial layer can control the crystallization process of the perovskite thin film and adjust the energy level alignment.
Guorong Zhou   +6 more
wiley   +1 more source

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