Ascorbyl Radicals as Reducing Agents in Copper-Catalyzed Redox Reactions. [PDF]
de Castro CB +9 more
europepmc +1 more source
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow +2 more
wiley +1 more source
Photocatalytic Nitrene Radical Anion Generation from Sulfonyl Azides for Intermolecular Aziridination of Unactivated Alkenes. [PDF]
Dam D +3 more
europepmc +1 more source
Engineering Bisubstrates to Target m6Am RNA Methyltransferases: Synthesis and Computational Studies
Use of the convertible nucleoside approach to synthesize m6Am RNA methyltransferase bisubstrates. This methodology allows for the introduction of modifications on the SAM analog moiety and the RNA substrate part, including the introduction of a cap analog by click chemistry.
Yoann Colas +3 more
wiley +1 more source
Photo-Triggered Hyaluronic Acid Hydrogel for 3D Culture and Cell Recovery. [PDF]
Palmieri F +8 more
europepmc +1 more source
Photocatalytic Vanadium‐Mediated Amination of Benzene With Hydroxylamine
Photochemical activation of N‐phenylphenothiazine (PPT) enables a selective direct benzene amination with hydroxylamine in the presence of various vanadium catalysts under mild reaction conditions. Spectroscopic and kinetic analyses identify a key vanadium(IV)‐hydroxylamine intermediate, elucidate the crucial roles of the acidic medium, the ...
Dana Králová +6 more
wiley +1 more source
Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda +5 more
wiley +1 more source
Synthesis of Ethynyl Trifluoromethyl Sulfide and Its Application to the Synthesis of CF<sub>3</sub>S-Containing Triazoles. [PDF]
Riesco-Domínguez A +3 more
europepmc +1 more source
A modular Rh‐catalyzed synthetic approach enabled the preparation of diverse reactive fragments from available substrates. The reactive fragments modified Aurora A kinase via several distinct modification reaction classes. In a complex biological environment, the constellation of modified proteins depended critically on the reactive fragment structure.
Julian Chesti +8 more
wiley +1 more source
Precise construction of spiro stereocenters <i>via</i> enantioselective radical addition through modulating photocatalysis from redox to energy transfer. [PDF]
Liu F +5 more
europepmc +1 more source

