Carbocycle editing of ketones proceeds via a radical-mediated bidirectional C-C bond cleavage/coupling strategy. [PDF]
Ma YJ +5 more
europepmc +1 more source
Click'n ROPISA: One‐Pot Synthesis of Ultrabright Fluorescent Nanoparticles Made of Polypeptides
Self‐assembly and fluorophore conjugation proceed rapidly in a one‐pot “Click'n ROPISA” process, yielding intensely fluorescent polypeptide nanoparticles with tunable visible emission. High dye loading enables efficient energy transfer and single‐particle visualization, while the straightforward synthesis provides versatile access to bright ...
Amin El Jarroudi Hammou +7 more
wiley +1 more source
Identification of chemical features for improved outer membrane permeation in mycobacteria using machine learning. [PDF]
Lepori I +19 more
europepmc +1 more source
This work demonstrates a layer‐bridging coordination strategy of Co single atoms in COFs that promotes the formation and utilization of triplet excited states. The introduction of Co single atoms induces pronounced energy‐level splitting and enhanced spin–orbit coupling, facilitating the generation of 1O2 and O2•– for efficient photocatalytic H2O2 ...
Guoen Tang +6 more
wiley +1 more source
Selective Monoreduction of 2,4 Diazido-Dideoxy Hexoses by Hydrogenation over Lindlar Catalyst. [PDF]
Wiener L +4 more
europepmc +1 more source
Bioorthogonal Tools for Ethanolamine Lipids and Protein Conjugates
An alkyne‐tagged ethanolamine analog (AlkEA) enables bioorthogonal, metabolic labeling of endogenous phosphatidylethanolamine (PE) and its protein modifications. AlkEA is incorporated into PE via the Kennedy pathway, allowing CuAAC‐based visualization of PE and affinity capture of PE‐conjugated LC3, ubiquitin, and GPI‐anchored proteins.
Yuan‐Ting Cho +5 more
wiley +1 more source
Molecular-Scale Analysis of Barium Azide (Ba(N<sub>3</sub>)<sub>2</sub>) Under High Pressure: A Synchrotron X-Ray Diffraction Study on Azide Ion Rotation and Phase Transition. [PDF]
Wu X +8 more
europepmc +1 more source
A Mechanical Planar Chiral Rotaxane Induces Single‐Handed Helicity in a Twisted Perylene Diimide
A mechanical planar chiral rotaxane (Rmp) is used to induce single‐handed helical chirality (M) in a perylene diimide chromophore, resulting in persistent circular dichroism (CD) and circularly polarised luminescence (CPL). ABSTRACT The twisting of chromophores such as perylene diimides (PDIs) into helical structures affords chiroptical properties from
Thomas E. Lawson +5 more
wiley +1 more source
SOLiD‐MaP: A Photoproximity Labeling Platform for Small Molecule Binding Site Mapping on RNA
SOLiD‐MaP is a ligand‐directed photoproximity labeling strategy developed for RNA binding‐site analysis. Singlet oxygen‐mediated labeling creates a proximity‐dependent chemical footprint of bound small molecules on RNA. Coupling this chemistry with mutational profiling enables identification of the ligand‐binding region at nucleotide resolution ...
Lin L. Rietveld +4 more
wiley +1 more source

