Results 231 to 240 of about 25,600 (309)

Synthesis of enantiomerically enriched β-substituted analogs of (S)-α-alanine containing 1-phenyl-1H-1,2,3-triazole groups. [PDF]

Amino Acids
Poghosyan AS, Khachatryan EA, Mkrtchyan AF, Mirzoyan V, Hovhannisyan AM, Ghazaryan KR, Minasyan EV, Langer P, Saghyan AS.   +8 more
europepmc   +1 more source

The Chemistry and Biology of the Tetrodotoxin Natural Product Family

Angewandte Chemie International Edition, Accepted Article.
Tetrodotoxin is a neurotoxic marine alkaloid, first isolated in 1909 from pufferfish and named after the biological order tetraodontiformes. Since its structural elucidation in 1964, it has attracted the interest of synthetic organic chemists due to its exceptional polarity, complex architecture, and important biological activity.
Benedikt Nißl, Marcel Mülbaier, Francesca Grisoni, Dirk Trauner, Marcel Bermúdez, Clemens Dialer, David B. Konrad   +6 more
wiley   +1 more source

Telescoped Flow Synthesis of Azacyclic Scaffolds Exploiting the Chromoselective Photolysis of Vinyl Azides and Azirines. [PDF]

Chemistry
Crawford R, Baumann M.
europepmc   +1 more source

Coordinative Ring‐Opening Polymerization of Limonene Carbamate towards Phosgene‐ and Isocyanate‐Free Polyurethane

Angewandte Chemie International Edition, Accepted Article.
This study presents a phosgene‐ and isocyanate‐free route for the synthesis of polyurethanes using (R)‐limonene as a bio‐based starting material. The synthesis of the cyclic limonene‐based carbamate monomer LU is achieved in high yields using dimethyl carbonate as a sustainable, less hazardous phosgene surrogate and is verified by NMR, SC‐XRD, ESI‐MS ...
Jonas Futter, Leon Ferdinand Richter, Stefanie Hörl, Bernhard Rieger, Moritz Kränzlein   +4 more
wiley   +1 more source

Heterobifunctional cross-linker with dinitroimidazole and azide modules for protein and oligonucleotide functionalization. [PDF]

RSC Adv
Luo Q, Liu S, Hua Y, Long C, Lv S, Li J, Zhang Y.   +6 more
europepmc   +1 more source

Intriguing Reactivity of a 1,2‐Dihydrodialumane Towards Organic Azides – From a Terminal Diazido–Dialumane to Pendulum‐Clock‐Like Azide Bridging

Angewandte Chemie International Edition, EarlyView.
The reaction of a dihydro‐dialane supported by a hybrid ligand (DNI) with organic azides yields structurally diverse aluminium species, including the first example of low oxidation state aluminium azide complex, a diazido‐dialane, along with an aluminium‐tetrazole, and azide alumination.
Xiaobai Wang, Franziska Traeger, Raphael F. Ligorio, Nico Graw, Regine Herbst‐Irmer, Anna Krawczuk, Malte Fischer, Dietmar Stalke   +7 more
wiley   +1 more source

Reactivity Profiling for High-Yielding Ynamine-Tagged Oligonucleotide Click Chemistry Bioconjugations. [PDF]

Bioconjug Chem
Peschke F, Taladriz-Sender A, Watson AJB, Burley GA.   +3 more
europepmc   +1 more source

Is Phenylnitrene a Missing Link in the Formation of Polycyclic Aromatic Nitrogen Heterocycles?

Angewandte Chemie International Edition, EarlyView.
A new formation pathway for polycyclic aromatic nitrogen heterocycles (PANHs) has been found. The reaction of phenylnitrene and the propargyl radical leads to quinoline, proving that nitrenes are suitable precursors for nitrogen incorporation mechanisms.
Rahel Arns, Rory McClish, Patrick Hemberger, Andras Bodi, Jordy Bouwman, Tina Kasper, Domenik Schleier   +6 more
wiley   +1 more source

N- to C-Peptide Synthesis, Arguably the Future for Sustainable Production. [PDF]

J Pept Sci
Ghosh K, Lubell WD.
europepmc   +1 more source

Imaging‐Based High‐Content Screening with Clickable Probes Identifies XPB Inhibitors

Angewandte Chemie International Edition, Accepted Article.
High‐content screening (HCS) has become a powerful tool in drug discovery; however, its reliance on indirect readouts and surrogate markers limits HCS’s ability to directly assess drug‐protein interactions at endogenous levels, particularly in subcellular contexts.
Shuqi Li, Hong-Rui Zhang, Yang Yang, Ben Chi-Bun Ko, Jin Shang, Haijun Guo, Dan Yang, Mankin Wong, Ricky Wing-Cheung Chan, Karen Ka-Yan Kung, Qian Zhao   +10 more
wiley   +1 more source