Results 101 to 110 of about 56,531 (323)
Spectrum of activity and mechanisms of azole–bisphosphonate synergy in pathogenic Candida
Candidiasis places a significant burden on human health and can range from common superficial vulvovaginal and oral infections to invasive diseases with high mortality.
Aidan Kane +5 more
doaj +1 more source
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg +3 more
wiley +1 more source
Treatment of Aspergillosis. [PDF]
Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Hoenigl, Martin, Jenks, Jeffrey D
core +1 more source
Epidemiological and genomic landscape of azole resistance mechanisms in Aspergillus fungi
Invasive aspergillosis is a life-threatening mycosis caused by the pathogenic fungus Aspergillus. The predominant causal species is Aspergillus fumigatus, and azole drugs are the treatment of choice.
Daisuke Hagiwara +3 more
doaj +1 more source
A Computational Study of the NMR Chemical Shifts of Polynitropyrazoles
The 1H, 13C, 15N, and 17O chemical shifts of 91 nitro‐1H‐pyrazoles at GIAO/B3LYP/6‐311++G(d,p) level. The calculated chemical shifts were compared with available experimental data using an empirical equation that relates absolute shieldings to chemical shifts.
Arturo Alcorta +3 more
wiley +1 more source
In vitro biofilms and antifungal susceptibility of dermatophyte and non-dermatophyte moulds involved in foot mycosis [PDF]
Tinea pedis and onychomycosis are among the commonest fungal diseases in the world. Dermatophytes and, less frequently, non-dermatophyte moulds are aetiological agents of foot mycosis and are capable of forming biofilms.
Bougnoux, Marie Élisabeth +5 more
core +1 more source
Overview of medically important antifungal azole derivatives [PDF]
Robert A. Fromtling
openalex +2 more sources
A series of tetrahydrochromene derivatives bearing triazole rings is synthesized via a one‐pot reaction. The process is optimized by ultrasonication of a basic aqueous tert‐butanol mixture. Subsequently, the optimized steps are successfully integrated into a four‐component, one‐pot protocol. The whole process was completed in less than 2 h.
Saeede Azhari +2 more
wiley +1 more source
Ueber die Wirkung der Chlormethylate einiger Azole auf Athmung und Kreislauf [PDF]
H. Tappeiner
openalex +1 more source
Azole antifungal contaminants disrupt mycorrhizal function and risk agricultural sustainability
Global food production is increasingly threatened by soil degradation, climate change and the rising costs of synthetic fertilisers. Circular agriculture, which promotes resource reuse, is a promising solution, but using treated wastewater and biosolids in farming introduces risks from emerging contaminants like pharmaceutical residues.
Emily K. Durant +5 more
wiley +1 more source

