Results 111 to 120 of about 30,366 (254)

On the evolution of azole resistance in Aspergillus fumigatus [PDF]

open access: yes, 2016
During the last decade azole resistance has increasingly been reported in Aspergillus fumigatus, which is a fungal pathogen involved in the vast majority of invasive aspergillosis infections in humans, and is now a global public health concern ...
Zhang, J.
core   +2 more sources

Sterol C-22 desaturase ERG5 mediates the sensitivity to antifungal azoles in Neurospora crassa and Fusarium verticillioides

open access: yesFrontiers in Microbiology, 2013
Antifungal azoles inhibit ergosterol biosynthesis by interfering with lanosterol 14α-demethylase. In this study, 7 upregulated and 4 downregulated ergosterol biosynthesis genes in response to ketoconazole treatment were identified in Neurospora crassa ...
Xianyun eSun   +7 more
doaj   +1 more source

Consensus‐based Guideline on tinea capitis

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The consensus‐based guideline developed under the auspices of the German Dermatological Society (DDG) is intended to provide physicians with a structured framework for clinical decision‐making in the management of patients with tinea capitis and to contribute to improved diagnostic accuracy, treatment adherence, and prevention. Tinea capitis is
Peter Mayser   +19 more
wiley   +1 more source

New Horizons in Antifungal Therapy

open access: yesJournal of Fungi, 2016
Recent investigations have yielded both profound insights into the mechanisms required by pathogenic fungi for virulence within the human host, as well as novel potential targets for antifungal therapeutics.
Kaila M. Pianalto, J. Andrew Alspaugh
doaj   +1 more source

Dose‐Adjusted Treatment With 7‐Day Venetoclax Plus Azacitidine or Decitabine in Patients With Acute Myeloid Leukaemia

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Acute myeloid leukaemia (AML) in older or unfit patients is commonly treated with hypomethylating agents (HMA) plus venetoclax (VEN), but prolonged VEN exposure often causes substantial haematological toxicity. We retrospectively analysed 61 elderly AML patients treated with HMA + VEN for 7 (7d), 14 (14d) or > 14 days (> 14d) per cycle.
Laurenz Steiner   +12 more
wiley   +1 more source

Emerging Deep Cutaneous Fungal Infection Caused by Cyphellophora Species in a Diabetic Patient

open access: yes
The Kaohsiung Journal of Medical Sciences, EarlyView.
Yi‐Shan Teng   +2 more
wiley   +1 more source

Mental Health Disorders in End‐Stage Kidney Disease: A Narrative Review of Clinical Considerations for Integrated Management

open access: yesHemodialysis International, EarlyView.
ABSTRACT Introduction End stage kidney disease (ESKD) is associated with a high prevalence of depression and anxiety, arising from both biological factors and the psychosocial burden of chronic dialysis care. Approximately 25%–30% of dialysis patients experience clinically significant depressive symptoms when assessed by structured clinical interview ...
Kunal Malhotra   +2 more
wiley   +1 more source

Epidemiology and Azole Resistance of Clinical Isolates of Aspergillus fumigatus from a Large Tertiary Hospital in Ningxia, China [PDF]

open access: yes
Yuting Kang,1,* Qiujie Li,2,* Yao Yao,3 Chao Xu,2 Zhuoran Qiu,2 Wei Jia,1,3 Gang Li,1,3 Pengtao Wang1 1Ningxia Key Laboratory of Clinical and Pathogenic Microbiology, Institute of Medical Sciences, General Hospital of Ningxia Medical University ...
Li G   +7 more
core  

Evolution of Dermatophytic Fungi: Anthropogenic and Biogenic Environmental Factors

open access: yesInternational Journal of Dermatology, EarlyView.
ABSTRACT Climate change presents new challenges to dermatologic care, ranging from anthropogenic factors, such as pollution that select for extremotolerant and potentially antifungal‐resistant fungi, to biogenic factors that can drive zoonotic outbreaks, which have received increased attention since the SARS‐CoV‐2 pandemic.
Aditya K. Gupta   +2 more
wiley   +1 more source

Chemical Composition and Anti-candida Activity of Trachyspermum ammi Essential Oil on Azoles Resistant Candida albicans Isolates from Oral Cavity of HIV+ Patients

open access: yesJournal of Medicinal Plants, 2013
Background: Oral candidiasis, caused by Candida albicans, is one of the most common infections in immunocompromised patients, especially in HIV+ individuals. Objective: The aims of this study were to evaluate the susceptibility of C. albicans isolates to
I Ashrafi Tamai   +4 more
doaj  

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