Results 101 to 110 of about 30,366 (254)
Azoles are one of a cyclic derivatives of chemical heterocyclic chemical and organic compounds including g a five member di unsaturated ring structure composed of bi nitrogen atoms at position (3 and 4) and one sulfur atom at position (1).
openaire +2 more sources
Epidemiological and genomic landscape of azole resistance mechanisms in Aspergillus fungi
Invasive aspergillosis is a life-threatening mycosis caused by the pathogenic fungus Aspergillus. The predominant causal species is Aspergillus fumigatus, and azole drugs are the treatment of choice.
Daisuke Hagiwara +3 more
doaj +1 more source
Use of loop-mediated isothermal amplification assays to detect azole-insensitive CYP51- overexpressing strains of Zymoseptoria tritici [PDF]
Septoria leaf blotch is currently controlled by programmed applications of multisite inhibitors (e.g. chlorothalonil), azoles (e.g. epoxiconazole and prothioconazole) and a new generation of Succinate Dehydrogenase Inhibitors (e.g.
Fraaije, B. A.
core +1 more source
Spectrum of activity and mechanisms of azole–bisphosphonate synergy in pathogenic Candida
Candidiasis places a significant burden on human health and can range from common superficial vulvovaginal and oral infections to invasive diseases with high mortality.
Aidan Kane +5 more
doaj +1 more source
For three collections of Irish Pyrenopeziza brassicae populations fungicide sensitivity status to methyl benzimidazole carbamate (MBC), quinone outside inhibitor (QoI) and succinate dehydrogenase inhibitor (SDHI) fungicides was determined using sensitivity screening in vitro. Molecular mechanisms of insensitivity have been identified for MBC and QoI in
Diana E Bucur +3 more
wiley +1 more source
Winter oilseed rape in Europe suffers frequent pathogen losses. This review outlines key integrated pest management (IPM) strategies, rotation, residue and tillage management, optimized sowing, resistance, and targeted fungicides supported by forecasting.
Jon S West +2 more
wiley +1 more source
The continuing significance of chiral agrochemicals
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
Molecular epidemiology of azole-resistant Aspergillus fumigatus in respiratory infections [PDF]
Aspergillus fumigatus is a ubiquitous ascomycete mould and the primary cause of aspergillosis which varies in severity and clinical presentation. Triazoles have been the most widely used antifungal agents in prophylaxis and treatment of Aspergillus ...
Abdolrasouli, Alireza
core +1 more source
In FMS‐like tyrosine kinase 3 (FLT3)‐mutated relapsed/refractory acute myeloid leukaemia, gilteritinib, azacitidine and venetoclax is an effective salvage option with an ORR of 100% (mCRc [MLFS + CRc] 93%). Sixty‐two per cent of patients treated with intention‐to‐transplant proceeded to allogeneic haematopoietic stem cell transplant, of whom 50% remain
Wei Yee Chan +19 more
wiley +1 more source
Summary Background and objectives Trichophyton indotineae is an emerging dermatophyte associated with chronic, recalcitrant dermatophytosis and terbinafine resistance due to squalene epoxidase (SQLE) mutations. We analyzed clinical characteristics, antifungal susceptibility profiles, SQLE mutations, and treatment outcomes of cases diagnosed in ...
Annabel H. Lechner +2 more
wiley +1 more source

