Results 101 to 110 of about 33,379 (274)

New Horizons in Antifungal Therapy

Journal of Fungi, 2016
Recent investigations have yielded both profound insights into the mechanisms required by pathogenic fungi for virulence within the human host, as well as novel potential targets for antifungal therapeutics.
Kaila M. Pianalto, J. Andrew Alspaugh
doaj   +1 more source

Molecular epidemiology of azole-resistant Aspergillus fumigatus in respiratory infections [PDF]

, 2019
Aspergillus fumigatus is a ubiquitous ascomycete mould and the primary cause of aspergillosis which varies in severity and clinical presentation. Triazoles have been the most widely used antifungal agents in prophylaxis and treatment of Aspergillus ...
Abdolrasouli, Alireza
core   +1 more source

Disease control in oilseed rape: Current insights and perspectives for next‐generation integrated pest management

Pest Management Science, EarlyView.
Winter oilseed rape in Europe suffers frequent pathogen losses. This review outlines key integrated pest management (IPM) strategies, rotation, residue and tillage management, optimized sowing, resistance, and targeted fungicides supported by forecasting.
Jon S West, Małgorzata Jędryczka, Nazanin Zamani‐Noor   +2 more
wiley   +1 more source

PDR16-mediated azole resistance in Candida albicans

, 2006
Many Candida albicans azole-resistant (AR) clinical isolates overexpress the CDR1 and CDR2 genes encoding homologous multidrug transporters of the ATP-binding cassette family.
Raymond, Martine, Saint-Germain, Goy, De Deken, Xavier, Saidane, Saloua, Weber, Sandra   +4 more
core   +1 more source

Absorption and translocation of 14C‐propiconazole associated with two adjuvants in young coffee plants

Pest Management Science, EarlyView.
Experimental workflow evaluating 14C‐propiconazole absorption and translocation in Coffea arabica with two biodegradable adjuvants, quantified at six post‐application time points using radioscanner and liquid scintillation spectrometry. Abstract BACKGROUND This study evaluated the absorption, translocation and distribution of 14C‐propiconazole applied ...
Valéria de Souza Ivo, Emerson Leite, José Mak, Valdemar Luiz Tornisielo, Kassio Ferreira Mendes   +4 more
wiley   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Chemical Composition and Anti-candida Activity of Trachyspermum ammi Essential Oil on Azoles Resistant Candida albicans Isolates from Oral Cavity of HIV+ Patients

Journal of Medicinal Plants, 2013
Background: Oral candidiasis, caused by Candida albicans, is one of the most common infections in immunocompromised patients, especially in HIV+ individuals. Objective: The aims of this study were to evaluate the susceptibility of C. albicans isolates to
I Ashrafi Tamai, T Zahraei Salehi, AR Khosravi, A Sharifzadeh, A Balal   +4 more
doaj  

Outcome Analysis of Breakthrough Invasive Aspergillosis on Anti-Mold Azole Prophylaxis and Treatment: 30-Year Experience in Hematologic Malignancy Patients

Journal of Fungi
Background: Anti-mold azoles have improved the outcomes of invasive aspergillosis (IA) when used therapeutically, but they are extensively used as prophylaxis.
Hiba Dagher, Anne-Marie Chaftari, Andrea Haddad, Ying Jiang, Jishna Shrestha, Robin Sherchan, Peter Lamie, Jennifer Makhoul, Patrick Chaftari, Ray Hachem, Issam Raad   +10 more
doaj   +1 more source

Covalent Organic Framework Electrolytes for Solid‐State Lithium Batteries: Designing Ion Highways for Next‐Generation Energy Storage

Small, EarlyView.
Covalent organic frameworks provide a structurally programmable platform for solid‐state lithium batteries. This review outlines a design framework linking structural descriptors to ion‐transport metrics. It examines mechanisms of confinement, channel architecture, and hybrid designs, addressing the reasons for the occasional failure of high intrinsic ...
Rajesh Dhanushkotti, Ningaraju G. N., Karthik C. S., Karthik V, Anil Kumar M R, Jitendrasingh Rajpurohit, Jeremy I. G. Dawkins, Karim Zaghib   +7 more
wiley   +1 more source

Alkylation-based optimization of antifungal FPPS inhibitors yields a potent, broad-spectrum lipophilic zoledronate derivative

mBio
Farnesyl pyrophosphate synthetase (FPPS) is a critical enzyme for squalene biosynthesis. In fungi, squalene is the primary substrate of the ergosterol biosynthesis pathway, which is the target of azole antifungals.
Aidan Kane, Felcia Lai, Joanna G. Rothwell, Thanh Thi Hue Dinh, Leona Campbell, Amy K. Cain, David Hibbs, Jane Hanrahan, Dee Carter   +8 more
doaj   +1 more source