Results 141 to 150 of about 58,246 (290)
Yeast‐Based Biotechnology for Civilian Security
Yeasts constitute robust and versatile eukaryotic platforms for biotechnological applications relevant to civilian security. Both native and genetically engineered yeast systems enable sensitive detection of chemical and biological hazards, effective removal of metals and organic pollutants, and detoxification of mycotoxins.
Justyna Ruchała +2 more
wiley +1 more source
In Vitro Biofilm Formation by Malassezia pachydermatis Isolates and Its Susceptibility to Azole Antifungals [PDF]
E. Čonková +3 more
openalex +1 more source
ABSTRACT Acute myeloid leukemia (AML) in elderly patients presents a major therapeutic challenge, as many are deemed unfit for intensive chemotherapy due to age, comorbidities, or frailty. Venetoclax in combination with hypomethylating agents (HMA) has emerged as a standard‐of‐care for this population, yet outcomes remain heterogeneous and predictive ...
Ernesto Vigna +11 more
wiley +1 more source
Probing the role of point mutations in the cyp51A gene from Aspergillus fumigatus in the model yeast Saccharomyces cerevisiae [PDF]
Azole-resistant strains of Aspergillus fumigatus have been detected and the underlying molecular mechanisms of resistance characterized. Point mutations in the cyp51A gene have been proved to be related to azole resistance in A.
Alcazar-Fuoli, L. +3 more
core
Effects of Hsp90 Inhibitor Ganetespib on Inhibition of Azole-Resistant Candida albicans [PDF]
Rui Yuan +4 more
openalex +1 more source
ABSTRACT Background Candida (Candidozyma) auris is an emerging yeast that poses a significant global health threat due to its multidrug resistance and ability to cause healthcare‐associated outbreaks. Genomic surveillance is essential for monitoring spread, transmission and antifungal resistance.
Luiz Marcelo Ribeiro Tomé +19 more
wiley +1 more source
BackgroundSolid organ transplant recipients on immunosuppressants such as tacrolimus are at increased risk of developing pulmonary aspergillosis, a severe to deadly complication with limited treatment options, especially against azole-resistant strains ...
Eliane Vanhoffelen +10 more
doaj +1 more source
A Rare Primary Pelvic Hydatid Cyst Presenting as Sciatica [PDF]
Primary hydatid cyst in the pelvis is rare, and usually presents with pressure symptoms affecting the adjacent abdominal organs. We describe a rare hydatid cyst which was eroding the sacral hallow, protruding into the right sciatic foramen and presenting
Bafna, UD +3 more
core
[Azole-resistant invasive aspergillosis].
Contains fulltext : 79815.pdf (Publisher’s version ) (Open Access)
Linden, J.W.M. van der +5 more
openaire +3 more sources
ABSTRACT Introduction Relapses occur in up to 40% of patients after prolonged courses of antifungal treatment for chronic pulmonary aspergillosis (CPA). The factors predisposing to relapse remain poorly defined. Methods We conducted a retrospective study of adults treated for ≥ 6 months with oral azoles for CPA.
Annabel Choyce +6 more
wiley +1 more source

