Results 151 to 160 of about 30,366 (254)

Genotype-Phenotype Relationships in Azole-Resistant <i>Aspergillus</i>: Two Sides of the Same Coin. [PDF]

J Fungi (Basel)
van Haren MHI, Melchers WJG, Zhang J, Dellière S, Bii CC, Stanford FA, Voetz M, White PL, Dyer PS, Pas SD, Verweij PE, Buil JB.   +11 more
europepmc   +1 more source

Recent Outbreaks, Resistance Trends, and Control Measures in <i>Candida auris</i> and <i>Candida glabrata</i> Infections. [PDF]

J Fungi (Basel)
Raeisi S, Madhavan P, Adisuri DS.
europepmc   +1 more source

Targeted azole prodrugs with antifungal activity [PDF]

Invasive fungal infections (IFIs), mostly caused by Aspergillus or Candida species, represent a severe global threat. IFIs are serious diseases of great concern especially in immunocompromised patiens, annually leading to more than 1.7 million deaths.1 ...
Černá, Lucie
core  

Human natural killer cells exhibit potent antifungal activity against azole-resistant <i>Aspergillus fumigatus</i> and diverse filamentous fungi. [PDF]

Microbiol Spectr
Namie H, Takazono T, Irifune S, Koga S, Ito Y, Nakada N, Hirayama T, Yoshida M, Takeda K, Ide S, Iwanaga N, Tashiro M, Hosogaya N, Sakamoto N, Okamura H, Tanaka Y, Yanagihara K, Nishino T, Mukae H, Izumikawa K.   +19 more
europepmc   +1 more source

The dual role of azoles: lifesaving antifungals and drivers of resistance - a One Health perspective. [PDF]

Nat Commun
Roohi B, Tyndall JDA, Svoboda T, de Hoog S, Crous PW, Monk BC, Strobl B, Weissenbacher A, Strauss J, Verweij PE, Lackner M.   +10 more
europepmc   +1 more source

Persistence of azole-resistant <i>Aspergillus fumigatus</i> in a southeastern United States environmental hotspot: a prospective genomic study. [PDF]

mSphere
Celia-Sanchez BN, Santos AR, Chavez J, Schwem B, Rediguieri BC, Misas E, Parnell L, Lockhart SR, Litvintseva AP.   +8 more
europepmc   +1 more source

Selectivity improvement of an azole inhibitor of CYP707A by replacing the monosubstituted azole with a disubstituted azole.

Selectivity improvement of an azole inhibitor of CYP707A by replacing the monosubstituted azole with a disubstituted azole.
application/pdf The plant growth-retardant uniconazole (UNI), a triazole inhibitor of gibberellin biosynthetic enzyme (CYP701A), inhibits multiple P450 enzymes including ABA 8'-hydroxylase (CYP707A), a key enzyme in ABA catabolism. Azole P450 inhibitors bind to a P450 active site by both coordinating to the heme-iron atom via sp2 nitrogen and ...
openaire  

The entire <i>CYP51B</i> locus in azole-resistant isolates of the dermatophyte <i>Trichophyton indotineae</i> revealed by optical genome mapping. [PDF]

Antimicrob Agents Chemother
Yamada T, Maeda M, Nakagawa M, Yaguchi T, Ishii M, Salamin K, Pich-Bavastro C, Monod M.   +7 more
europepmc   +1 more source

The azole antifungal drugs [PDF]

Journal of Antimicrobial Chemotherapy, 1987
openaire   +2 more sources

Sexual reproduction and the polygenic architecture of azole resistance in agricultural populations of <i>Aspergillus fumigatus</i>. [PDF]

Front Microbiol
Huang J, Liu H, He Y, Zhang Y.
europepmc   +1 more source