Results 91 to 100 of about 40,795 (299)

Combined antifungal resistance and biofilm tolerance: the global threat of Candida auris [PDF]

open access: yes, 2019
The enigmatic yeast Candida auris has emerged over the last decade and rapidly penetrated our consciousness. The global threat from this multidrug-resistant yeast has generated a call to arms from within the medical mycology community.
Kean, Ryan, Ramage, Gordon
core   +2 more sources

Important of Azoles

open access: yesAmerican International Journal of Biology and Life Sciences, 2019
Azoles are one of a cyclic  derivatives  of chemical  heterocyclic chemical and organic compounds including g a five member di unsaturated ring structure composed of  bi  nitrogen atoms at position (3 and 4) and one sulfur atom at position (1).        Most of prepared  work
openaire   +2 more sources

Visualization of Gaseous Ammonia Using an Ionic Liquid‐Based pH‐Responsive Dye

open access: yesAnalysis &Sensing, EarlyView.
An ionic liquid composed of bromocresol purple ([P66614]2[BCP]) is synthesized via an ion‐exchange reaction. The color of [P66,614]2[BCP] changes from yellow to blue after exposure to gaseous NH3. The color change in the [P66614]2[BCP] thin film serves as a visual indicator of pork and salmon decomposition.
Naoya Adachi   +3 more
wiley   +1 more source

Challenges in optimizing tacrolimus therapy in patients treated with rifampin: A case series

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Tacrolimus is a cornerstone immunosuppressant in transplantation medicine with a narrow therapeutic window. Drug–drug interactions with strong CYP3A4 and P‐glycoprotein modulators, such as rifampin and azole antifungals, significantly alter tacrolimus exposure and complicate therapy. Two transplant cases illustrates the impact of rifampin on tacrolimus
Jeroen P. A. Houwen   +6 more
wiley   +1 more source

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

open access: yesChemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

Absent in vitro interaction between chloroquine and antifungals against Aspergillus fumigatus [PDF]

open access: yes, 2017
This work was supported by Medical Mycology Section, Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Seyedmousavi, Seyedmojtaba   +3 more
core   +1 more source

Cycloaddition and Annulation Reactions with Donor‐Acceptor Cyclobutanes

open access: yesHelvetica Chimica Acta, EarlyView.
Reviewing the rise of donor‐acceptor cyclobutanes in (4 + 2) annulations, from Lewis/Brønsted acid to electrocatalysis, enabling stereoselective access to complex heterocycles and natural products. Abstract Donor‐acceptor (DA) cyclobutanes are emerging as valuable synthetic intermediates due to their ring strain and polarized C─C bonds, which allow for
Emma G. L. Robert, Jerome Waser
wiley   +1 more source

A transcriptomic approach for evaluating the relative potency and mechanism of action of azoles in the rat Whole Embryo Culture. [PDF]

open access: yes, 2017
We evaluated the effect of six azoles on embryonic development in the rat whole embryo culture (WEC). Using the total morphological scoring system (TMS), we calculated the ID10concentration (effective dose for 10% decrease in TMS).
Dimopoulou, Myrto   +5 more
core   +3 more sources

Distribution and Antimicrobial Resistance of Pathogenic Bacteria in Patients With Sternal Osteomyelitis

open access: yesiLABMED, EarlyView.
This study conducted a retrospective analysis of microbiological culture results and antimicrobial resistance patterns in patients with sternal osteomyelitis at a tertiary medical center. The primary pathogens causing sternal osteomyelitis were gram‐positive bacteria. Infections with multidrug‐resistant organisms were also relatively common among these
Yumin Yang   +5 more
wiley   +1 more source

Frequency and molecular epidemiology of Aspergillus isolated from patients with suspicion of respiratory fungal infection [PDF]

open access: yes, 2019
Objective: The aim of this study was to determine the frequency of Aspergillus detected in respiratory samples from a cohort of patients with suspicion of fungal infection of the respiratory tract as well as to determine the susceptibility to azoles of ...
Oliveira, M.   +3 more
core  

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