Abstract Background After pharmaceutical benefits scheme approval of midostaurin for fms‐like tyrosine kinase 3 (FLT3)‐mutated acute myeloid leukaemia (AML) in 2018, the Australasian Leukaemia & Lymphoma Group (ALLG) proposed a consensus approach to AML induction with 7+3 chemotherapy (7 days of infusional cytarabine with three doses of anthracycline ...
Aditya Tedjaseputra+19 more
wiley +1 more source
Ueber die Wirkung der Chlormethylate einiger Azole auf Athmung und Kreislauf [PDF]
H. Tappeiner
openalex +1 more source
Fungal dysbiosis following antibacterial monotherapy in canine otitis externa
Objectives To evaluate evidence of Malassezia overgrowth following successful topical antibacterial monotherapy of refractory canine bacterial otitis using semi‐quantitative cultures. Materials and Methods Twenty‐nine dogs with bacterial otitis were treated topically with either fluoro‐quinolone [0.5% enrofloxacin (18 dogs, 19 treatment events, 25 ears)
J. Juhola+7 more
wiley +1 more source
Organotin(IV) Derivatives of Azoles
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire +4 more sources
Treatment outcomes in sinonasal aspergillosis in dogs in the United Kingdom: 436 cases (2011‐2021)
Objectives A variety of treatment options for sinonasal aspergillosis have been described, encompassing non‐invasive and invasive approaches. To describe the clinical outcomes in dogs treated for sinonasal aspergillosis in the United Kingdom. Materials and Methods A multi‐centre retrospective survey was performed involving 23 referral centres in the ...
C. D. Prior+44 more
wiley +1 more source
Azole-Associated Pseudohyperaldosteronism: A Class Effect or Azole-Specific? [PDF]
Adam J. DiPippo+1 more
openaire +2 more sources
Antifungal Drugs for Invasive Candida Infections (ICI) in Neonates: Future Perspectives
Fungal infections may complicate the neonatal clinical course, and the spectrum of therapies for their treatment in the perinatal period is limited. Polyenes, Azoles and Echinocandins represent the three classes of antifungal drugs commonly used in the ...
Iliana Bersani+6 more
doaj +1 more source
Substrate Prediction for RiPP Biosynthetic Enzymes via Masked Language Modeling and Transfer Learning [PDF]
Ribosomally synthesized and post-translationally modified peptide (RiPP) biosynthetic enzymes often exhibit promiscuous substrate preferences that cannot be reduced to simple rules. Large language models are promising tools for predicting such peptide fitness landscapes.
arxiv
Single‐Dose, Intravenous, and Oral Pharmacokinetics of Isavuconazole in Dogs
ABSTRACT Isavuconazole, a triazole antifungal used in humans for invasive fungal infections, may be effective for treating canine fungal infections, although data on its use in dogs is limited. This study aimed to determine the pharmacokinetics and safety of a single dose of isavuconazole in dogs, administered both intravenously and orally. Six healthy
Yishan Kuo+3 more
wiley +1 more source
1H- and 13C-NMR Spectra of Phenyl-substituted Azole Derivatives. II. A Conformational Study. [PDF]
Mikael Begtrup+5 more
openalex +1 more source