Results 91 to 100 of about 22,992 (261)

Ratifying the efficacy and safety of intensive induction chemotherapy for acute myeloid leukaemia by the Australasian Leukaemia & Lymphoma Group consensus approach

open access: yesInternal Medicine Journal, Volume 55, Issue 5, Page 749-759, May 2025.
Abstract Background After pharmaceutical benefits scheme approval of midostaurin for fms‐like tyrosine kinase 3 (FLT3)‐mutated acute myeloid leukaemia (AML) in 2018, the Australasian Leukaemia & Lymphoma Group (ALLG) proposed a consensus approach to AML induction with 7+3 chemotherapy (7 days of infusional cytarabine with three doses of anthracycline ...
Aditya Tedjaseputra   +19 more
wiley   +1 more source

Fungal dysbiosis following antibacterial monotherapy in canine otitis externa

open access: yesJournal of Small Animal Practice, Volume 66, Issue 3, Page 149-157, March 2025.
Objectives To evaluate evidence of Malassezia overgrowth following successful topical antibacterial monotherapy of refractory canine bacterial otitis using semi‐quantitative cultures. Materials and Methods Twenty‐nine dogs with bacterial otitis were treated topically with either fluoro‐quinolone [0.5% enrofloxacin (18 dogs, 19 treatment events, 25 ears)
J. Juhola   +7 more
wiley   +1 more source

Organotin(IV) Derivatives of Azoles

open access: yesChemInform, 1999
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +4 more sources

Treatment outcomes in sinonasal aspergillosis in dogs in the United Kingdom: 436 cases (2011‐2021)

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives A variety of treatment options for sinonasal aspergillosis have been described, encompassing non‐invasive and invasive approaches. To describe the clinical outcomes in dogs treated for sinonasal aspergillosis in the United Kingdom. Materials and Methods A multi‐centre retrospective survey was performed involving 23 referral centres in the ...
C. D. Prior   +44 more
wiley   +1 more source

Antifungal Drugs for Invasive Candida Infections (ICI) in Neonates: Future Perspectives

open access: yesFrontiers in Pediatrics, 2019
Fungal infections may complicate the neonatal clinical course, and the spectrum of therapies for their treatment in the perinatal period is limited. Polyenes, Azoles and Echinocandins represent the three classes of antifungal drugs commonly used in the ...
Iliana Bersani   +6 more
doaj   +1 more source

Substrate Prediction for RiPP Biosynthetic Enzymes via Masked Language Modeling and Transfer Learning [PDF]

open access: yesarXiv
Ribosomally synthesized and post-translationally modified peptide (RiPP) biosynthetic enzymes often exhibit promiscuous substrate preferences that cannot be reduced to simple rules. Large language models are promising tools for predicting such peptide fitness landscapes.
arxiv  

Single‐Dose, Intravenous, and Oral Pharmacokinetics of Isavuconazole in Dogs

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Isavuconazole, a triazole antifungal used in humans for invasive fungal infections, may be effective for treating canine fungal infections, although data on its use in dogs is limited. This study aimed to determine the pharmacokinetics and safety of a single dose of isavuconazole in dogs, administered both intravenously and orally. Six healthy
Yishan Kuo   +3 more
wiley   +1 more source

1H- and 13C-NMR Spectra of Phenyl-substituted Azole Derivatives. II. A Conformational Study. [PDF]

open access: bronze, 1974
Mikael Begtrup   +5 more
openalex   +1 more source

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