Results 111 to 120 of about 7,725 (230)

Therapeutic Tools for Vulvovaginal Candidiasis: Current and Emerging Antifungal Agents

Journal of Fungi
Vulvovaginal candidiasis (VVC) represents a widespread gynaecological challenge, affecting approximately 75% of women at some point during their reproductive years, with a significant subset progressing to recurrent forms (RVVC).
Guillermo Quindós, Iker De-la-Pinta, Cristina Marcos-Arias, Nerea Jauregizar, Elena Sevillano, Lucila Madariaga, Elena Eraso   +6 more
doaj   +1 more source

Systemic treatment of cutaneous leishmaniasis: A systematic review and meta‐analysis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This systematic review and meta‐analysis assessed systemic treatments for cutaneous leishmaniasis across 83 studies and 4603 patients. Treatment efficacies of meglumine antimoniate, miltefosine, azoles, pentamidine, and liposomal amphotericin B varied by region and species. Miltefosine showed consistent evidence across multiple settings.
Maximilian Egg, Dennis Wienand, Lucie Harpain, Marie‐Luise Brunner‐Kovarik, Julia Walochnik, Markus Wiesmueller, Amélie Hampel, Tibor Spath, Lukas Trnka, Judit Simon, Alessandra Handisurya   +10 more
wiley   +1 more source

Regulation of ABC Transporters and Ergosterol Biosynthesis by the Transcription Factor FvADS-1 Controls Azole Resistance and Virulence in Fusarium verticillioides

Journal of Fungi
Fusarium verticillioides is a significant agricultural pathogen and an emerging causative agent of invasive fusariosis in clinical settings. Fusarium species frequently exhibit resistance to available antifungal agents, yet the molecular mechanisms ...
Yajing Yin, Hanxing Zhang, Zhenying Zhang, Mi Zhou, Shaojie Li, Chengcheng Hu   +5 more
doaj   +1 more source

Table_1_Synergistic Effects and Mechanisms of Combined Treatment With Harmine Hydrochloride and Azoles for Resistant Candida albicans.docx

, 2019
Several studies have demonstrated the significant antiviral, antimicrobial, antiplasmodial, antioxidative, antifungal, antimutagenic, and antitumor properties of harmine hydrochloride (HMH).
Yan Gao (93649), Lina Hao (755332), Xiuyun Li (655391), Xuexin Wu (7497422)   +3 more
core   +1 more source

Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers

Journal of Periodontal Research, EarlyView.
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed, Christof E. Dörfer   +1 more
wiley   +1 more source

Trapping of Thiocarbonyl Ylides with NH-Azoles; A Novel Route to N-Substituted Azoles

, 1998
The thermal decomposition of 2,5-dihydro-1,3,4-thiadiazoles (1) in the presence of imidazole, pyrazole, 3-phenylpyrazole, and 1,2,4-triazole, respectively, yielded S,N-acetals of type 4.
Gendek, Tomasz, Heimgartner, Heinz, Mlostoń, Grzegorz; https://orcid.org/   +2 more
core   +1 more source

Shifting Epidemiology and Antifungal Susceptibility Patterns of Clinical Fungal Isolates in an Intensive Care Unit (ICU) from Bucharest, Romania: A Retrospective Observational Study

Antibiotics
Background: Antifungal resistance among Candida species represents a growing clinical challenge, particularly in the context of increasing prevalence of non-albicans species. Methods: We conducted a retrospective analysis of 747 fungal isolates collected
Madalina (Preda) Solomon, Beatrice Mahler, Oana Popescu, Lia-Mara Ditu, Irina Gheorghe-Barbu, Laura Ioana Chivu, Loredana Sabina Cornelia Manolescu   +6 more
doaj   +1 more source

The Future of Azoles in Agriculture—Balancing Effectiveness and Toxicity

Azole compounds are extensively utilized in plant protection products for managing pests and diseases in both agriculture and horticulture. Moreover, azoles are the most extensively used class of fungicides worldwide.
Ivana Majić, Andrea Dandić, Maja Karnaš Babić, Vesna Rastija   +3 more
core   +1 more source

Uptake of azoles by lamb's lettuce (Valerianella locusta L.) grown in hydroponic conditions

, 2016
An uptake and translocation study of azole compounds was performed in lamb's lettuce (Valerianella locusta L.) grown in nutrient solution fortified with different azoles.
Escorial, Concepción, Tadeo Lluch, José Luis, Molero Vega, M. Encarnación, García Valcárcel, Ana Isabel, Loureiro, Íñigo   +4 more
core   +1 more source

Characterization of Sec14 Domain–Containing Proteins in the Malaria Parasite Plasmodium falciparum

Molecular Microbiology, EarlyView.
During asexual blood‐stage development, P. falciparum Sec14 proteins display distinct localizations suggesting specialized roles in lipid exchange. PfSec14‐1 initially localizes to the nucleus before moving to the ER and Golgi alongside PfSec14‐4 during schizogony.
Florian Lauruol, Dominik Šťastný, J. Pedro Fernandez‐Murray, Christopher R. McMaster, Peter Griač, Dave Richard   +5 more
wiley   +1 more source