Results 101 to 110 of about 23,173 (263)

Copper(II)-Catalyzed Dehydrogenative Cross-Coupling between Two Azoles [PDF]

open access: yes, 2016
The copper­(II)-catalyzed dehydrogenative coupling between two different azoles for the preparation of unsymmetrical biazoles has been developed.
Xurong Qin (1627105)   +6 more
core   +1 more source

Emergence of Trichophyton indotineae in Switzerland (2014–2025): Clinical analysis and antifungal susceptibility

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Trichophyton indotineae is an emerging dermatophyte associated with chronic, recalcitrant dermatophytosis and terbinafine resistance due to squalene epoxidase (SQLE) mutations. We analyzed clinical characteristics, antifungal susceptibility profiles, SQLE mutations, and treatment outcomes of cases diagnosed in ...
Annabel H. Lechner   +2 more
wiley   +1 more source

Copper-Catalyzed C–H Alkoxylation of Azoles [PDF]

open access: yes, 2016
We achieved copper-catalyzed intramolecular and intermolecular alkoxylation of azoles. This reaction is a rare example of transition-metal-catalyzed C–H alkoxylation of heteroaromatic compounds.
Noriaki Takemura (1991890)   +2 more
core   +1 more source

The role of azoles in the management of azole-resistant aspergillosis: From the bench to the bedside

open access: yesDrug Resistance Updates, 2014
Azole resistance is an emerging problem in Aspergillus fumigatus and is associated with a high probability of treatment failure. An azole resistance mechanism typically decreases the activity of multiple azole compounds, depending on the mutation. As alternative treatment options are limited and in some isolates the minimum inhibitory concentration ...
Seyedmousavi, S.   +4 more
openaire   +3 more sources

Consensus‐based Guideline on tinea capitis

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The consensus‐based guideline developed under the auspices of the German Dermatological Society (DDG) is intended to provide physicians with a structured framework for clinical decision‐making in the management of patients with tinea capitis and to contribute to improved diagnostic accuracy, treatment adherence, and prevention. Tinea capitis is
Peter Mayser   +19 more
wiley   +1 more source

AN OVERVIEW OF THE AZOLES OF INTEREST [PDF]

open access: yes, 2015
In the last years, the risk of human fungal infections has been extensively increased with the increasing immune suppressed patients. Fortunately, the therapy of fungal infections has been undergone an explosive period of development.
El-garhy, Omar H.
core  

Academia / Industry Collaborations towards the Functionalization of Aryl Azoles [PDF]

open access: yes
Aryl azoles can be found in numerous active pharmaceutical ingredients (APIs). Milvexian is a Factor Xia inhibitor currently in phase III for the treatment of thrombotic events containing an ortho-substituted 1-aryl-1H-1,2,3-triazole moiety.
Broggini, Diego, Wagschal, Simon
core   +2 more sources

Decarboxylative C-H cross-coupling of azoles [PDF]

open access: yes, 2010
(Figure Presented) Côte d'Azole: The title reaction demon-strates the use of diverse oxazoles 2 as suitable substrates in cross-coupling reactions with azole-5-carboxylic acids 1 under palladium catalysis in the presence of copper carbonate. The reaction
Greaney, Michael F.   +3 more
core   +1 more source

Mental Health Disorders in End‐Stage Kidney Disease: A Narrative Review of Clinical Considerations for Integrated Management

open access: yesHemodialysis International, EarlyView.
ABSTRACT Introduction End stage kidney disease (ESKD) is associated with a high prevalence of depression and anxiety, arising from both biological factors and the psychosocial burden of chronic dialysis care. Approximately 25%–30% of dialysis patients experience clinically significant depressive symptoms when assessed by structured clinical interview ...
Kunal Malhotra   +2 more
wiley   +1 more source

Theoretical study on novel nitrogen-rich energetic compounds of bis(amino)-azobis(azoles) with tetrazene unit [PDF]

open access: yes, 2012
Six stereoisomers of 5,5'-bis(amino)-1,1'-azobis(tetrazoles) and 30 other structures, including all possible bis(amino)-azobis(azoles) with an N-N=N-N unit, were designed. The molecular geometries were fully optimized at the DFT-B3LYP level with the 6-31+
曾丹丹   +8 more
core   +1 more source

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