Results 81 to 90 of about 23,173 (263)

Pyrvinium Pamoate Synergizes with Azoles in vitro and in vivo to Exert Antifungal Efficacy Against Candida auris and Other Candida Species [PDF]

open access: yes
Jinqing Zhang,1,* Gaolian Li,2,* Jing Hu,3,* Jingwen Tan,4 Heng Zhang,5 Yizheng Zhou5 1Department of Dermatology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Gynaecology ...
Li G   +5 more
core   +1 more source

Alternative developmental toxicity models for assessing the in vivo embryotoxicity of azoles [PDF]

open access: yes, 2018
The implementation of regulations for protecting both humans and the environment from potential chemical health hazards, as well as the increase of global pressure for reducing, refining and replacing animal experiments promote the development and ...
Dimopoulou, Myrto
core   +2 more sources

Azole-Resistance in Aspergillus terreus and Related Species: An Emerging Problem or a Rare Phenomenon?

open access: yesFrontiers in Microbiology, 2018
Objectives: Invasive mold infections associated with Aspergillus species are a significant cause of mortality in immunocompromised patients. The most frequently occurring aetiological pathogens are members of the Aspergillus section Fumigati followed by ...
Tamara Zoran   +53 more
doaj   +1 more source

Protein‐Based High‐Performance Liquid Chromatography and Cyclodextrin‐Capillary Electrokinetic Chromatography for the Chiral Separation of Azoles

open access: yesELECTROPHORESIS, EarlyView.
Human serum albumin‐based high‐performance liquid chromatography and cyclodextrin‐based capillary electrokinetic chromatography were used for the chiral separation of azoles. Although only two of the five tested azoles could be enantioseparated by liquid chromatography, all of them were separated by capillary electrokinetic chromatography using single ...
Sarah Moreau   +3 more
wiley   +1 more source

Antifungal Susceptibility of Malassezia pachydermatis Isolates from Companion Animals and Genomic Insights into Resistance Mechanisms

open access: yesAntibiotics
Background/Objectives: Malassezia pachydermatis is a lipophilic yeast frequently associated with otitis externa and dermatological disorders in companion animals. This study aimed to evaluate the antifungal susceptibility of M.
Marianna Domán   +5 more
doaj   +1 more source

The stepwise selection for ketoconazole resistance induces upregulation of C14-demethylase (CYP51) in Leishmania amazonensis

open access: yesMemorias do Instituto Oswaldo Cruz, 2012
Ketoconazole is a clinically safe antifungal agent that also inhibits the growth of Leishmania spp. A study was undertaken to determine whether Leishmania parasites are prone to becoming resistant to ketoconazole by upregulating C14-demethylase after ...
Valter Viana Andrade-Neto   +5 more
doaj   +1 more source

Table_1_Synergistic Effects and Mechanisms of Combined Treatment With Harmine Hydrochloride and Azoles for Resistant Candida albicans.docx [PDF]

open access: yes, 2019
Several studies have demonstrated the significant antiviral, antimicrobial, antiplasmodial, antioxidative, antifungal, antimutagenic, and antitumor properties of harmine hydrochloride (HMH).
Yan Gao (93649)   +3 more
core   +1 more source

Nickel-Catalyzed Direct Arylation of Azoles with Aryl Bromides [PDF]

open access: yes, 2016
Nickel catalyst systems for the direct C2 arylation of oxazoles and thiazoles have been developed. The catalyst systems are cost-efficient and allow the use of various aryl bromides in the C−H arylation of ...
Hitoshi Hachiya (2191477)   +3 more
core   +1 more source

Important of Azoles

open access: yesAmerican International Journal of Biology and Life Sciences, 2019
Azoles are one of a cyclic  derivatives  of chemical  heterocyclic chemical and organic compounds including g a five member di unsaturated ring structure composed of  bi  nitrogen atoms at position (3 and 4) and one sulfur atom at position (1).
openaire   +2 more sources

Sensitivity of Irish Pyrenopeziza brassicae populations to methyl benzimidazole carbamate (MBC), quinone outside inhibitor (QoI) and succinate dehydrogenase inhibitor (SDHI) fungicides

open access: yesPest Management Science, EarlyView.
For three collections of Irish Pyrenopeziza brassicae populations fungicide sensitivity status to methyl benzimidazole carbamate (MBC), quinone outside inhibitor (QoI) and succinate dehydrogenase inhibitor (SDHI) fungicides was determined using sensitivity screening in vitro. Molecular mechanisms of insensitivity have been identified for MBC and QoI in
Diana E Bucur   +3 more
wiley   +1 more source

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