Results 71 to 80 of about 7,725 (230)

AN OVERVIEW OF THE AZOLES OF INTEREST [PDF]

open access: yes, 2015
In the last years, the risk of human fungal infections has been extensively increased with the increasing immune suppressed patients. Fortunately, the therapy of fungal infections has been undergone an explosive period of development.
El-garhy, Omar H.
core   +1 more source

A General Copper-Catalyzed Coupling of Azoles with Vinyl Bromides

open access: yes, 2016
A copper-catalyzed methodology for the coupling of vinyl bromides with azoles has been developed. This protocol uses a combination of 10 mol % of copper iodide and 20 mol % of ethylenediamine as catalyst.
Qian Liao (1489453)   +3 more
core   +1 more source

Azole-Resistance in Aspergillus terreus and Related Species: An Emerging Problem or a Rare Phenomenon?

open access: yesFrontiers in Microbiology, 2018
Objectives: Invasive mold infections associated with Aspergillus species are a significant cause of mortality in immunocompromised patients. The most frequently occurring aetiological pathogens are members of the Aspergillus section Fumigati followed by ...
Tamara Zoran   +53 more
doaj   +1 more source

Palladium-Catalyzed Direct Oxidative Alkenylation of Azoles

open access: yes, 2016
The direct heteroaromatic sp2 C−H alkenylation of 2-substituted azole compounds with alkenes proceeds in the presence of Pd(OAc)2 and AgOAc as catalyst and oxidant, respectively, to afford the corresponding 5-alkenylated azoles in good ...
Mitsuru Miyasaka (2233909)   +3 more
core   +1 more source

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima   +6 more
wiley   +1 more source

Antifungal Susceptibility of Malassezia pachydermatis Isolates from Companion Animals and Genomic Insights into Resistance Mechanisms

open access: yesAntibiotics
Background/Objectives: Malassezia pachydermatis is a lipophilic yeast frequently associated with otitis externa and dermatological disorders in companion animals. This study aimed to evaluate the antifungal susceptibility of M.
Marianna Domán   +5 more
doaj   +1 more source

The stepwise selection for ketoconazole resistance induces upregulation of C14-demethylase (CYP51) in Leishmania amazonensis

open access: yesMemorias do Instituto Oswaldo Cruz, 2012
Ketoconazole is a clinically safe antifungal agent that also inhibits the growth of Leishmania spp. A study was undertaken to determine whether Leishmania parasites are prone to becoming resistant to ketoconazole by upregulating C14-demethylase after ...
Valter Viana Andrade-Neto   +5 more
doaj   +1 more source

Prediction of Prion Proteins in E. coli Based on Bimodal Sequence Characteristics

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Prions are infectious proteins that bear misfolded conformations capable of converting folded states into misfolded aggregates under physiologically relevant conditions. In mammals, prions cause deadly maladies including Creutzfeldt‐Jakob and chronic wasting disease. To date, several prion proteins have been identified in eukaryotes, primarily
Katherine Shreeve   +5 more
wiley   +1 more source

Sensitivity of Irish Pyrenopeziza brassicae populations to methyl benzimidazole carbamate (MBC), quinone outside inhibitor (QoI) and succinate dehydrogenase inhibitor (SDHI) fungicides

open access: yesPest Management Science, EarlyView.
For three collections of Irish Pyrenopeziza brassicae populations fungicide sensitivity status to methyl benzimidazole carbamate (MBC), quinone outside inhibitor (QoI) and succinate dehydrogenase inhibitor (SDHI) fungicides was determined using sensitivity screening in vitro. Molecular mechanisms of insensitivity have been identified for MBC and QoI in
Diana E Bucur   +3 more
wiley   +1 more source

Corrosion Protection of Copper Using Azoles Applied on Its Surface at High Temperature Under Vacuum

open access: yesInternational Journal of Electrochemical Science, 2011
Application of seven different azoles namely; 1H-Pyrazole-3,5-diamine (azole 1), 1-Benzoyl benzotriazole (azole 2), 1-P-Chloro-Benzoyl benzotriazole (azole3), 1-P-Methoxy-Benzoyl benzotriazole (azole 4), 4-Phenyl-1H-pyrazole-3,5-diamine (azole5), N ...
F. M. Al Kharafi   +4 more
doaj   +1 more source

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