Results 121 to 130 of about 23,046 (254)

Synthesis, Characterization, and Anti‐Plasmodium falciparum Activity of a New Copper(II) Complex Containing 2‐(Tert‐Butoxy)‐6‐(1H‐imidazol‐1‐yl)pyridine

ChemMedChem, Volume 21, Issue 11, 15 June 2026.
The graphical abstract illustrates the formation of a Cu(II) complex from azole‐based ligand, highlighting metal–ligand synergy. The resulting coordination compound acts as a bioactive entity against Plasmodium, where metal coordination enhances antiparasitic activity, outperforming the free ligand and demonstrating its potential as an antimalarial ...
Alexander Patiño‐Cubides, María Camila Velasco‐Pareja, Mario A. Macías, María F. Yasnot‐Acosta, Ana Rodriguez, Augusto Valderrama‐Aguirre, John J. Hurtado   +6 more
wiley   +1 more source

Table_1_Synergistic Effects and Mechanisms of Combined Treatment With Harmine Hydrochloride and Azoles for Resistant Candida albicans.docx

, 2019
Several studies have demonstrated the significant antiviral, antimicrobial, antiplasmodial, antioxidative, antifungal, antimutagenic, and antitumor properties of harmine hydrochloride (HMH).
Yan Gao (93649), Lina Hao (755332), Xiuyun Li (655391), Xuexin Wu (7497422)   +3 more
core   +1 more source

Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II

European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.
Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley   +1 more source

Fungicidal Activity and In Silico Studies of Triazoles Derived From Glycerol Against Neocosmospora falciformis, A Causal Agent of Guava Tree Decline

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Among seventeen 1,2,3‐triazoles synthetized from glycerol (4a–4q), compound 4l completely inhibited mycelial growth and eliminated N. falciformis spores at 1,000 µg/mL, exhibiting enhanced antifungalactivity and strong binding within the FsCYP51 active site, which highlights its promise as a lead candidate for antifungal development in both biological ...
Adilson Vidal Costa, Arêssa de Oliveira Correia, Breno Benvindo dos Anjos, Mariana Belizario de Oliveira, Poliana Aparecida Rodrigues Gazolla, Vagner Tebaldi de Queiroz, Juliana Alves Resende, Róbson Ricardo Teixeira, Osmair Vital de Oliveira, Gabriel Jacomin Vargas, Waldir Cintra de Jesus Júnior, Willian Bucker Moraes, Fábio Ramos Alves   +12 more
wiley   +1 more source

Nickel-Catalyzed Direct Arylation of Azoles with Aryl Bromides

, 2016
Nickel catalyst systems for the direct C2 arylation of oxazoles and thiazoles have been developed. The catalyst systems are cost-efficient and allow the use of various aryl bromides in the C−H arylation of ...
Hitoshi Hachiya (2191477), Koji Hirano (1452925), Tetsuya Satoh (1489648), Masahiro Miura (308443)   +3 more
core   +1 more source

Light‐Driven [2 + 2] Cycloaddition Strategies for the Synthesis of Cyclobuta[b]indoles and Their Derivatives

ChemPhotoChem, Volume 10, Issue 6, June 2026.
This review surveys the literature on light‐driven dearomative [2+2] cycloadditions of indoles, highlighting their power to access complex cyclobuta[b]indole frameworks. Advances in photocatalysis, sensitizer design, and reaction engineering enable selective and sustainable assembly of strained three‐dimensional architectures, expanding opportunities ...
Maria Chiara Cabua, Davide Moi, Alberto Luridiana, Francesco Secci, Emanuele Cocco   +4 more
wiley   +1 more source

A case of double‐mutant resistant tinea indotineae

JEADV Clinical Practice
In recent years, there has been a concerning increase in a challenging‐to‐treat dermatophyte lineage of the Trichophyton mentagrophytes complex, known as Trichophyton indotineae. We report the first case of resistant T.
R. Koncan, A. Benini, G. Lo Cascio, N. Di Meo, V. Lepera, G. Palladino, L. Clemente, F. Barbone, I. Zalaudek   +8 more
doaj   +1 more source

Adaptation Under Pressure: Resistance and Stress Response Interplay in Clinical Aspergillus fumigatus Isolates

Journal of Fungi
Understanding the interplay between antifungal resistance, stress adaptation, and virulence in Aspergillus fumigatus is critical for more effective treatment outcomes. In this study, we investigate six clinical isolates of A. fumigatus from the hospitals
Ivana Segéňová, Ján Víglaš, Tomáš Pagáč, Petra Olejníková   +3 more
doaj   +1 more source

EHA Guidelines on management of chronic lymphocytic leukemia and Richter transformation

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract Previous editions of the European guidelines for the management of chronic lymphocytic leukemia (CLL) were developed by experts in CLL under the auspices of the European Society for Medical Oncology (ESMO). These previous editions have served as a reference text for many physicians caring for patients with CLL.
Barbara Eichhorst, Paolo Ghia, Francesc Bosch, Ruth Clifford, Michael Gregor, Romain Guieze, Arnon P. Kater, Carsten U. Niemann, Sarka Pospisilova, Tadeusz Robak, Anna Schuh, Kostas Stamatopoulos, Tamar Tadmor, Nick York   +13 more
wiley   +1 more source

Mutación r30q en cyp51a de neocosmospora solani asociada a resistencia a azoles

, 2021
Neocosmospora and Fusarium are the etiological agents of human fusariosis such as onychomycosis, fungal keratitis and disseminated infections, and the most widely reported species are Neocosmospora keratoplastica, Neocosmospora falciformis and Fusarium ...
Lizcano Salas, Andrés Felipe
core