Results 11 to 20 of about 40,795 (299)

The Lipid Composition of Azole-sensitive and Azole-resistant Strains of Candida albicans [PDF]

Microbiology, 1986
The lipid compositions of two azole-sensitive (A and B2630) and two azole-resistant (AD and KB) strains of the opportunistic fungal pathogen Candida albicans were studied by using several lipid extraction procedures: no differences were observed between the lipid content or total phospholipid/neutral lipid ratios of the four strains.
Christopher A. Hitchcock, Keith Barrett‐Bee, Nicholas J. Russell   +2 more
openalex   +4 more sources

Farmacología de los azoles [PDF]

Revista Iberoamericana de Micología, 2007
Azole antifungals have different pharmacokinetic characteristics: complete oral absorption for Voriconazole, and to a lesser extent for fluconazole. The absorption of posaconazole and itraconazole increases with food intake.
Azanza, J.R. (José Ramón), Garcia-Quetglas, E. (Emilio), Sadaba, B. (Belén)   +2 more
core   +5 more sources

The Synergistic Effect of Tacrolimus (FK506) or Everolimus and Azoles Against Scedosporium and Lomentospora Species In Vivo and In Vitro

Frontiers in Cellular and Infection Microbiology, 2022
Scedosporium and Lomentospora infections in humans are generally chronic and stubborn. The use of azoles alone cannot usually inhibit the growth of these fungi.
Zikuo Wang, Mei Liu, Luyao Liu, Linyun Li, Lihua Tan, Yi Sun   +5 more
doaj   +1 more source

Azole Fungicides and Their Endocrine Disrupting Properties: Perspectives on Sex Hormone-Dependent Reproductive Development

Frontiers in Toxicology, 2022
Azoles are antifungal agents used in both agriculture and medicine. They typically target the CYP51 enzyme in fungi and, by so doing, disrupt cell membrane integrity. However, azoles can also target various CYP enzymes in mammals, including humans, which
Monica Kam Draskau, Terje Svingen
doaj   +1 more source

Evaluation of the inhibitory effect of azoles on pharmacokinetics of lenvatinib in rats both in vivo and in vitro by UPLC‐MS/MS

Thoracic Cancer, 2023
Background Lenvatinib is a multitargeted tyrosine kinase inhibitor used in the treatment of a variety of solid tumors. This study aims to investigate the potential pharmacokinetic interactions between lenvatinib and various azoles (ketoconazole ...
Mengming Xia, Xueyi Song, Zebei Lu, Yu Wang, Quan Zhou, Peiwu Geng, Shuanghu Wang, Yunfang Zhou, Qingjun Wu, Aixia Han   +9 more
doaj   +1 more source

Evaluation of Antibacterial and Anticandidal Activities of Some Imidazole, Benzimidazole and Benztriazole Derivatives [PDF]

Trends in Pharmaceutical Sciences, 2022
In recent years, resistance to conventional antimicrobial drugs has become a serious concern in the clinic. Hence, the discovery of novel and effective antimicrobial agents with improved properties is of great value.
Sara Sadeghian, Ahmad Gholami, Soghra Khabnadideh, Razieh Razmi, Issa Sadeghian, Younes Ghasemi, Zahra Rezaei   +6 more
doaj   +1 more source

Recent Developments in Transition-Metal Catalyzed Direct C–H Alkenylation, Alkylation, and Alkynylation of Azoles

Molecules, 2020
The transition metal-catalyzed C–H bond functionalization of azoles has emerged as one of the most important strategies to decorate these biologically important scaffolds. Despite significant progress in the C–H functionalization of various heteroarenes,
Su Chen, Prabhat Ranjan, Leonid G. Voskressensky, Erik V. Van der Eycken, Upendra K. Sharma   +4 more
doaj   +1 more source

Antifungal Resistance in Clinical Isolates of Candida glabrata in Ibero-America

Journal of Fungi, 2021
In different regions worldwide, there exists an intra-and inter-regional variability in the rates of resistance to antifungal agents in Candida glabrata, highlighting the importance of understanding the epidemiology and antifungal susceptibility profiles
Erick Martínez-Herrera, María Guadalupe Frías-De-León, Rigoberto Hernández-Castro, Eduardo García-Salazar, Roberto Arenas, Esther Ocharan-Hernández, Carmen Rodríguez-Cerdeira   +6 more
doaj   +1 more source

Systematic review of topical treatments for fungal infections of the skin and nails of the feet [PDF]

, 1999
OBJECTIVE: To identify and synthesise the evidence for efficacy and cost effectiveness of topical treatments for superficial fungal infections of the skin and nails of the feet. DESIGN: Systematic review. INTERVENTIONS: Topical treatments for superficial
Bell-Syer, Sally E.M., Crawford, Fay, Hart, Rachel, Russell, Ian, Torgerson, David J., Young, Philip   +5 more
core   +2 more sources

Analysis of imidazoles and triazoles in biological samples after MicroExtraction by packed sorbent [PDF]

, 2017
This paper reports the MEPS-HPLC-DAD method for the simultaneous determination of 12 azole drugs (bifonazole, butoconazole, clotrimazole, econazole, itraconazole, ketoconazole, miconazole, posaconazole, ravuconazole, terconazole, tioconazole and ...
Campestre, Cristina, Locatelli, Marcello, Guglielmi, Paolo, De Luca, Elisa, Bellagamba, Giuseppe, Menta, Sergio, Zengin, Gokhan, Celia, Christian, Di Marzio, Luisa, Carradori, Simone   +9 more
core   +1 more source