Results 11 to 20 of about 34,737 (245)
Frontiers in Cellular and Infection Microbiology, 2022 Scedosporium and Lomentospora infections in humans are generally chronic and stubborn. The use of azoles alone cannot usually inhibit the growth of these fungi.
Zikuo Wang +5 more
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Frontiers in Toxicology, 2022 Azoles are antifungal agents used in both agriculture and medicine. They typically target the CYP51 enzyme in fungi and, by so doing, disrupt cell membrane integrity. However, azoles can also target various CYP enzymes in mammals, including humans, which
Monica Kam Draskau, Terje Svingen
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Emergence and Genomic Characterization of Multidrug Resistant Candida auris in Nigeria, West Africa
Journal of Fungi, 2022 Candida auris is an emerging multidrug-resistant fungal pathogen that has become a worldwide public health threat due to the limitations of treatment options, difficulty in diagnosis, and its potential for clonal transmission.
Rita Oladele +5 more
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Thoracic Cancer, 2023 Background Lenvatinib is a multitargeted tyrosine kinase inhibitor used in the treatment of a variety of solid tumors. This study aims to investigate the potential pharmacokinetic interactions between lenvatinib and various azoles (ketoconazole ...
Mengming Xia +9 more
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Emerging Trends in the Use of Topical Antifungal-Corticosteroid Combinations
Journal of Fungi, 2022 A broad range of topical antifungal formulations containing miconazole or terbinafine as actives are commonly used as efficacious choices for combating fungal skin infections.
Dalibor Mijaljica +2 more
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Systematic review of topical treatments for fungal infections of the skin and nails of the feet [PDF]
, 1999 OBJECTIVE: To identify and synthesise the evidence for efficacy and cost effectiveness of topical treatments for superficial fungal infections of the skin and nails of the feet. DESIGN: Systematic review. INTERVENTIONS: Topical treatments for superficial
Bell-Syer, Sally E.M. +5 more
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Molecules, 2020 The transition metal-catalyzed C–H bond functionalization of azoles has emerged as one of the most important strategies to decorate these biologically important scaffolds. Despite significant progress in the C–H functionalization of various heteroarenes,
Su Chen +4 more
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Antifungal Resistance in Clinical Isolates of Candida glabrata in Ibero-America
Journal of Fungi, 2021 In different regions worldwide, there exists an intra-and inter-regional variability in the rates of resistance to antifungal agents in Candida glabrata, highlighting the importance of understanding the epidemiology and antifungal susceptibility profiles
Erick Martínez-Herrera +6 more
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Allergic bronchopulmonary aspergillosis: diagnostic and treatment challenges [PDF]
, 2016 Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder, occurring mostly in asthmatic and cystic fibrosis patients, caused by an abnormal T-helper 2 lymphocyte response of the host to Aspergillus fumigatus antigens.
CINICOLA, BIANCA LAURA +3 more
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Intravenous posaconazole: key features of clinical pharmacology and practical applications
Онкогематология, 2022 Invasive fungal infections in various categories of patients remain one of the most urgent problems of modern medicine. This is complicated by the imperfection of diagnostic methods, as well as a small range of antimycotics for systemic use.
A. V. Veselov, N. N. Klimko
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