Results 31 to 40 of about 34,899 (249)

A transcriptomic approach for evaluating the relative potency and mechanism of action of azoles in the rat Whole Embryo Culture. [PDF]

open access: yes, 2017
We evaluated the effect of six azoles on embryonic development in the rat whole embryo culture (WEC). Using the total morphological scoring system (TMS), we calculated the ID10concentration (effective dose for 10% decrease in TMS).
Dimopoulou, Myrto   +5 more
core   +9 more sources

Antifungal Resistance in Dermatophytes: Genetic Considerations, Clinical Presentations and Alternative Therapies

open access: yesJournal of Fungi, 2021
Numerous reports describe the emergence of resistance in dermatophytes, especially in T. rubrum and T. mentagrophytes/indotineae strains. We here present a review of the current status of resistance in dermatophytes worldwide.
Rosalie Sacheli, Marie-Pierre Hayette
doaj   +1 more source

Screening of the central nervous system in children with invasive pulmonary aspergillosis [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Broenen, Emmi   +5 more
core   +2 more sources

Clotrimazole-Induced Oxidative Stress Triggers Novel Yeast Pkc1-Independent Cell Wall Integrity MAPK Pathway Circuitry

open access: yesJournal of Fungi, 2021
Azoles are one of the most widely used drugs to treat fungal infections. To further understand the fungal response to azoles, we analyzed the MAPK circuitry of the model yeast Saccharomyces cerevisiae that operates under treatment with these antifungals.
Ángela Sellers-Moya   +3 more
doaj   +1 more source

Exploring hidden dimensions of soil fungal biodiversity: A simple technique to detect soil fungi resistant to antifungal compounds [PDF]

open access: yes, 2010
Soils are known to be ultimate and complex reservoirs of microbial diversity. The complex dimensions of bacterial and fungal diversity in tropical soils and microbial community dynamics are underexplored.
Nandkumar M. Kamat   +1 more
core   +2 more sources

Nuclear Quadrupole Resonance Spectroscopy: Tautomerism and Structure of Functional Azoles

open access: yesCrystals, 2019
The Nuclear Quadrupole Resonance spectroscopy data of functionalized azoles (imidazoles, triazoles and corresponding benzazoles) are reviewed and critically discussed. The possibility of studying the tautomerism of azoles by the NQR method is considered.
Lyudmila I. Larina
doaj   +1 more source

Challenges in Ramularia collo-cygni Control

open access: yesEncyclopedia, 2022
Ramularia leaf spot (RLS), caused by the fungus Ramularia collo-cygni, has recently become widespread in Europe. Succinate dehydrogenase inhibitor (SDHI) and demethylation inhibitor (DMI) fungicides are mainly applied for disease control on barley fields,
Andres Mäe, Riinu Kiiker
doaj   +1 more source

Antifungal Drug Plasma Exposures: A Possible Contribution of Vitamin D-Related Gene Variants

open access: yesPharmaceuticals, 2022
Vitamin D (VD) seems to influence drug clearance and outcome. Antifungal drugs (AFU) are the most used azoles in clinical practice. In the literature, no data are available concerning VD’s impact on AFU therapy. The aim of this study was to analyze if VD
Jessica Cusato   +12 more
doaj   +1 more source

Cyp7b1-inhibiting azoles enhance hematopoietic stem and progenitor cell mobilization in normal and sickle cell disease mice

open access: yesHaematologica
Mobilized hematopoietic stem and progenitor cells (HSPCs) are essential for transplantationbased therapies, including curative gene therapies for sickle cell disease (SCD).
Brandon L. Vu   +5 more
doaj   +1 more source

Trichosporon asahii Infective Endocarditis of Prosthetic Valve: A Case Report and Literature Review

open access: yesAntibiotics, 2023
Trichosporon spp. endocarditis is a severe and hard-to-treat infection. Immunosuppressed subjects and carriers of prosthetic valves or intracardiac devices are at risk.
Alice Mulè   +13 more
doaj   +1 more source

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