Results 11 to 20 of about 23,173 (263)
Azole Use in Agriculture, Horticulture, and Wood Preservation – Is It Indispensable?
Frontiers in Cellular and Infection Microbiology, 2021 Plant pathogens cause significant damage to plant products, compromising both quantities and quality. Even though many elements of agricultural practices are an integral part of reducing disease attacks, modern agriculture is still highly reliant on ...
Lise Nistrup Jørgensen +1 more
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Susceptibility Profile of Candida albicans Biofilms on Polyvinyl Chloride Endotracheal Tube to Antifungal Azoles [PDF]
, 2020 One of the most prevalent causative organisms in human fungal infections is Candida albicans. The extensive utility of medical devices such as endotracheal tube has resulted in the increased cases of fungal infections.
Nelson R. Villarante +11 more
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Épidémiologie des candidoses systémiques dans les services à haut risque au CHU et au centre anti cancer de Batna –Algérie. [PDF]
Batna Journal of Medical Sciences, 2022 Background: Systemic candidiasis are serious conditions responsible for high mortality. The objective of this work is to describe the epidemiology of systemic candidiasis in high-risk departments at the UHC and the ACC of BATNA. Patients and methods:
Ouanassa Hamouda, Allaoua Hichem Fendri
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Glutamine metabolism modulates azole susceptibility in Trypanosoma cruzi amastigotes
eLife, 2020 The mechanisms underlying resistance of the Chagas disease parasite, Trypanosoma cruzi, to current therapies are not well understood, including the role of metabolic heterogeneity.
Peter C Dumoulin +4 more
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Nature Communications, 2022 1,2-Azoles are privileged structures in many natural products and drugs. The authors report an atroposelective synthesis of two types of axially chiral 1,2-azoles, through vinylidene ortho-quinone methide intermediates.
Yu Chang +6 more
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Frontiers in Cellular and Infection Microbiology, 2022 Scedosporium and Lomentospora infections in humans are generally chronic and stubborn. The use of azoles alone cannot usually inhibit the growth of these fungi.
Zikuo Wang +5 more
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Formal Nucleophilic Substitution of Bromocyclopropanes with Azoles [PDF]
, 2016 A highly diastereoselective protocol for the formal nucleophilic substitution of 2-bromocyclopropylcarboxamides with azoles is described. A wide range of azoles, including pyrroles, indoles, benzimidazoles, pyrazoles, and benzotriazoles, can be ...
Jack Xu (2096188) +3 more
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Frontiers in Toxicology, 2022 Azoles are antifungal agents used in both agriculture and medicine. They typically target the CYP51 enzyme in fungi and, by so doing, disrupt cell membrane integrity. However, azoles can also target various CYP enzymes in mammals, including humans, which
Monica Kam Draskau, Terje Svingen
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Azoles: Biological Activities and Synthetic Pathways [PDF]
, 2023 With an increase in patients with suppressed immune system during the past few years, the danger of human fungal infections has significantly grown. There has been a rapid progress in the field of fungal infection treatment.
Amol K. Kharde, Vinod R. Kadu
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Emergence and Genomic Characterization of Multidrug Resistant Candida auris in Nigeria, West Africa
Journal of Fungi, 2022 Candida auris is an emerging multidrug-resistant fungal pathogen that has become a worldwide public health threat due to the limitations of treatment options, difficulty in diagnosis, and its potential for clonal transmission.
Rita Oladele +5 more
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