Results 11 to 20 of about 7,725 (230)

Nuclear Quadrupole Resonance Spectroscopy: Tautomerism and Structure of Functional Azoles

open access: yesCrystals, 2019
The Nuclear Quadrupole Resonance spectroscopy data of functionalized azoles (imidazoles, triazoles and corresponding benzazoles) are reviewed and critically discussed. The possibility of studying the tautomerism of azoles by the NQR method is considered.
Lyudmila I. Larina
doaj   +2 more sources

Preparation and Utility of N-Alkynyl Azoles in Synthesis

open access: yesMolecules, 2019
Heteroatom-substituted alkynes have attracted a significant amount of interest in the synthetic community due to the polarized nature of these alkynes and their utility in a wide range of reactions.
Brandon Reinus, Sean M. Kerwin
doaj   +2 more sources

Galactose Inhibits the Translation of Erg1 that Enhances the Antifungal Activities of Azoles Against Candida albicans

open access: yesAntibiotics
Background/Objectives: The diminished efficacy of azoles in treating fungal infections is attributed to the emergence of resistance among pathogenic fungi. Employing a synergistic approach with other compounds to enhance the antifungal activity of azoles
Sijin Hang   +7 more
doaj   +2 more sources

Emergence and Genomic Characterization of Multidrug Resistant Candida auris in Nigeria, West Africa

open access: yesJournal of Fungi, 2022
Candida auris is an emerging multidrug-resistant fungal pathogen that has become a worldwide public health threat due to the limitations of treatment options, difficulty in diagnosis, and its potential for clonal transmission.
Rita Oladele   +5 more
doaj   +1 more source

Emerging Trends in the Use of Topical Antifungal-Corticosteroid Combinations

open access: yesJournal of Fungi, 2022
A broad range of topical antifungal formulations containing miconazole or terbinafine as actives are commonly used as efficacious choices for combating fungal skin infections.
Dalibor Mijaljica   +2 more
doaj   +1 more source

Evaluation of the inhibitory effect of azoles on pharmacokinetics of lenvatinib in rats both in vivo and in vitro by UPLC‐MS/MS

open access: yesThoracic Cancer, 2023
Background Lenvatinib is a multitargeted tyrosine kinase inhibitor used in the treatment of a variety of solid tumors. This study aims to investigate the potential pharmacokinetic interactions between lenvatinib and various azoles (ketoconazole ...
Mengming Xia   +9 more
doaj   +1 more source

Platinum and gold catalysis: à la carte hydroamination of terminal activated allenes with azoles [PDF]

open access: yes, 2019
Nucleophilic additions to allenes catalyzed by transition metals represent a powerful tool to get selective access to diverse structures with numerous applications. Reported here is a straightforward methodology to achieve selective addition of azoles to
Alonso, José Miguel   +3 more
core   +1 more source

Antifungal Resistance in Clinical Isolates of Candida glabrata in Ibero-America

open access: yesJournal of Fungi, 2021
In different regions worldwide, there exists an intra-and inter-regional variability in the rates of resistance to antifungal agents in Candida glabrata, highlighting the importance of understanding the epidemiology and antifungal susceptibility profiles
Erick Martínez-Herrera   +6 more
doaj   +1 more source

Susceptibility Profile of Candida albicans Biofilms on Polyvinyl Chloride Endotracheal Tube to Antifungal Azoles

open access: yes, 2020
One of the most prevalent causative organisms in human fungal infections is Candida albicans. The extensive utility of medical devices such as endotracheal tube has resulted in the increased cases of fungal infections.
Nelson R. Villarante   +11 more
core   +1 more source

Study of Different Chiral Columns for the Enantiomeric Separation of Azoles Using Supercritical Fluid Chromatography

open access: yesSeparations, 2022
The enantiomeric separation of antifungal compounds is an arduous task in pharmaceutical and biomedical fields due to the different properties that each diastereoisomer presents.
Laura Toribio   +5 more
doaj   +1 more source

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