Results 41 to 50 of about 7,725 (230)

In vitro Resistance Pattern of Selected Antifungal Azoles against Candida albicans Biofilms on Silicone Nasogastric Tube

, 2019
Prolonged use of implanted medical devices has been linked with device-associated infections. Since enteral tube feeding is increasing worldwide, the present study described the morphology of Candida albicans biofilms on the surface of silicone ...
Nelson R. Villarante, Nina G. Gloriani, Villarante, Nelson R., Salazar, Pauline Bridgette D., Pauline Bridgette D. Salazar, Sumalapao, Derick Erl P., Alegre, Frederico Martin D., Derick Erl P. Sumalapao, Frederico Martin D. Alegre, Gloriani, Nina G.   +9 more
core   +1 more source

Azoles

, 2014
Capítulo cuarto del temario del segundo bloque de la asignatura Ampliación de Química Orgánica Avanzada. Azoles.
Raoul Herbrecht, Yasmine Nivoix
openaire   +3 more sources

LAM Genes Contribute to Environmental Stress Tolerance but Sensibilize Yeast Cells to Azoles

Frontiers in Microbiology, 2020
Lam proteins transport sterols between the membranes of different cellular compartments. In Saccharomyces cerevisiae, the LAM gene family consists of three pairs of paralogs.
Svyatoslav S. Sokolov, Margarita A. Vorobeva, Alexandra I. Smirnova, Alexandra I. Smirnova, Ekaterina A. Smirnova, Nataliya I. Trushina, Nataliya I. Trushina, Kseniia V. Galkina, Kseniia V. Galkina, Fedor F. Severin, Dmitry A. Knorre, Dmitry A. Knorre   +11 more
doaj   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

Advanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song, Can Zhao, Qiaoling Wang, Hongjiao Zhang, Xiao Liu, Linqi Wang, Michael Bromley, Wen‐Bing Yin   +7 more
wiley   +1 more source

Impact of concomitant azoles on ruxolitinib treatment in patients with GVHD: post hoc analyses of REACH2 and REACH3

Blood Advances
: Azole antifungal agents, commonly used for preventing invasive fungal infections in graft-versus-host disease (GVHD), are known to affect ruxolitinib metabolism.
Zahra Mahmoudjafari, Emily Kintsch, Zhenyi Xue, Valkal Bhatt, John Galvin, Franco Locatelli, Robert Zeiser   +6 more
doaj   +1 more source

Palladium-catalyzed desulfitative arylation of azoles with arylsulfonyl hydrazides

, 2012
Palladium-catalyzed desulfitative and denitrogenative arylation of azoles with arylsulfonyl hydrazides has been achieved. A broad scope of azoles and arylsulfonyl hydrazides has been used to produce arylated azoles in high ...
Wan, Boshun, Yu, Xinzhang, Li, Xingwei
core   +1 more source

The MoSR‐MoDde1 Regulatory Axis: A Novel Determinant of DMI Sensitivity and a Target for Sustainable Rice Blast Control

Advanced Science, EarlyView.
The transcription factor MoSR governs DMI fungicide sensitivity in Magnaporthe oryzae through dual regulation of ergosterol biosynthesis and the detoxification enzyme MoDde1. Targeting MoDde1 via a small‐molecule inhibitor or host‐induced gene silencing enhances DMI efficacy against rice blast, offering a sustainable disease management strategy ...
Fan‐Zhu Meng, Wen‐Kai Wei, Meng‐Yao Wu, Min‐Zheng Cai, Yu‐Fu Wang, Li Zhao, Shuai Meng, Liang‐Fen Yin, Guido Schnabel, Wei‐Xiao Yin, Chao‐Xi Luo   +10 more
wiley   +1 more source

One-pot synthesis of benzofused heteroaryl azoles via tandem C-heteroatom coupling/C–H activation of azoles

, 2011
The Cu(i) or Pd(ii)-catalyzed cross-couplings of gem-dihaloolefins with azoles via tandem C-heteroatom coupling/C–H activation for the preparation of benzofused heteroaryl azoles have been developed.
Jingsong You, Xurong Qin, Jingbo Lan, Dongbing Zhao, Xuefeng Cong   +4 more
core   +1 more source

Pharmacovigilance analysis of myopathy associated with azoles and nonstatins interactions based on US FAERS database

Scientific Reports
Azoles are first-line antifungal agents known to increase the risk of statin-related myopathy due to drug interactions. However, myopathy events have also been observed in patients using azoles without concurrent statin use, suggesting that azoles may be
Shen’ao Jing, Xue Zhang, Ying Zhang, Nan’nan Sun, Xiang’dong Du, Xuan Wang, Xin Huang, Xia Zhao, Yi Han   +8 more
doaj   +1 more source

Direct Arylation of Simple Azoles Catalyzed by 1,10-Phenanthroline Containing Palladium Complexes: An Investigation of C4 Arylation of Azoles and the Synthesis of Triarylated Azoles by Sequential Arylation

, 2016
Direct triarylation and sequential triarylation reactions of simple azoles catalyzed by [Pd(phen)2]PF6 are described. Simple azoles, such as N-methylimidazole, thiazole, and oxazole, were observed to undergo triaryaltion reactions even at their C4 ...
Toshiaki Murai (1402201), Eiji Yamaguchi (1447486), Fumitoshi Shibahara (1490908)   +2 more
core   +1 more source