Results 21 to 30 of about 23,173 (263)
Emerging Trends in the Use of Topical Antifungal-Corticosteroid Combinations
A broad range of topical antifungal formulations containing miconazole or terbinafine as actives are commonly used as efficacious choices for combating fungal skin infections.
Dalibor Mijaljica +2 more
doaj +1 more source
Background Lenvatinib is a multitargeted tyrosine kinase inhibitor used in the treatment of a variety of solid tumors. This study aims to investigate the potential pharmacokinetic interactions between lenvatinib and various azoles (ketoconazole ...
Mengming Xia +9 more
doaj +1 more source
Antifungal Resistance in Clinical Isolates of Candida glabrata in Ibero-America
In different regions worldwide, there exists an intra-and inter-regional variability in the rates of resistance to antifungal agents in Candida glabrata, highlighting the importance of understanding the epidemiology and antifungal susceptibility profiles
Erick Martínez-Herrera +6 more
doaj +1 more source
The plant growth-retardant uniconazole (UNI), a triazole inhibitor of gibberellin biosynthetic enzyme (CYP701A), inhibits multiple P450 enzymes including ABA 8'-hydroxylase (CYP707A), a key enzyme in ABA catabolism. Azole P450 inhibitors bind to a P450 active site by both coordinating to the heme-iron atom via sp2 nitrogen and interacting with ...
Yasushi, Todoroki +6 more
openaire +2 more sources
Platinum and gold catalysis: à la carte hydroamination of terminal activated allenes with azoles [PDF]
Nucleophilic additions to allenes catalyzed by transition metals represent a powerful tool to get selective access to diverse structures with numerous applications. Reported here is a straightforward methodology to achieve selective addition of azoles to
Alonso, José Miguel +3 more
core +1 more source
In vitro Resistance Pattern of Selected Antifungal Azoles against Candida albicans Biofilms on Silicone Nasogastric Tube [PDF]
Prolonged use of implanted medical devices has been linked with device-associated infections. Since enteral tube feeding is increasing worldwide, the present study described the morphology of Candida albicans biofilms on the surface of silicone ...
Nelson R. Villarante +9 more
core +1 more source
The enantiomeric separation of antifungal compounds is an arduous task in pharmaceutical and biomedical fields due to the different properties that each diastereoisomer presents.
Laura Toribio +5 more
doaj +1 more source
Palladium-catalyzed desulfitative arylation of azoles with arylsulfonyl hydrazides [PDF]
Palladium-catalyzed desulfitative and denitrogenative arylation of azoles with arylsulfonyl hydrazides has been achieved. A broad scope of azoles and arylsulfonyl hydrazides has been used to produce arylated azoles in high ...
Wan, Boshun, Yu, Xinzhang, Li, Xingwei
core +1 more source
One-pot synthesis of benzofused heteroaryl azoles via tandem C-heteroatom coupling/C–H activation of azoles [PDF]
The Cu(i) or Pd(ii)-catalyzed cross-couplings of gem-dihaloolefins with azoles via tandem C-heteroatom coupling/C–H activation for the preparation of benzofused heteroaryl azoles have been developed.
Jingsong You +4 more
core +1 more source
Azole resistance of Malassezia pachydermatis causing treatment failure in a dog
A 5-year-old neutered female toy Poodle chronically treated with systemic and topical azoles to control recurrent Malassezia dermatitis/otitis was presented because of the loss of treatment efficacy.
Martina Angileri +3 more
doaj +1 more source

