Results 211 to 220 of about 41,065 (312)

The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14alpha demethylase in Candida albicans

, 1997
Theodore C. White
openalex   +1 more source

Pharmacists' views on the implementation of therapeutic drug monitoring in oncology

Journal of Pharmacy Practice and Research, Volume 55, Issue 5, Page 414-421, October 2025.
Abstract Background There is increasing interest in the potential benefit of therapeutic drug monitoring (TDM) in oncology. However, uptake in Australian hospitals is limited. Aim This study sought to explore hospital pharmacists' experiences with TDM in oncology, seeking to determine if they could provide insights into barriers and facilitators to its
Jane E. Carland, Bridin Murnion, Thomas Sakellaris, Jana Stojanova   +3 more
wiley   +1 more source

Antifungal Agents in the 21st Century: Advances, Challenges, and Future Perspectives. [PDF]

Infect Dis Rep
Branda F, Petrosillo N, Ceccarelli G, Giovanetti M, De Vito A, Madeddu G, Scarpa F, Ciccozzi M.   +7 more
europepmc   +1 more source

Evaluation of the Antifungal Properties of Azomethine‐Pyrazole Derivatives from a Structural Perspective

ChemistryOpen, Volume 14, Issue 10, October 2025.
A series of azomethine‐pyrazole derivatives bearing a para‐substituted azo‐phenyl ring is straightforwardly prepared. The new compounds display an elevated antifungal activity against various Candida species and Cryptococcus neoformans strains. DFT and molecular docking calculations are used to determine possible routes of action through interactions ...
María Isabel Murillo, Andrés Camilo Restrepo‐Acevedo, Cristian Rocha‐Roa, Susana Zacchino, Laura Svetaz, Simón Hernández‐Ortega, Rodrigo Abonia, Ronan Le Lagadec, Fernando Cuenú‐Cabezas   +8 more
wiley   +1 more source

The serine palmitoyl transferase of plant pathogenic fungi: a promising new target for the development of novel crop protection solutions†

Pest Management Science, Volume 81, Issue 10, Page 6567-6578, October 2025.
High biological activity of pyridazine carboxamides against a wide range of Ascomycetes led to identification of a new biochemical target for agrochemical fungicides – serine palmitoyl transferase. Abstract BACKGROUND Plant pathogens pose a significant threat to global agriculture and, thus to world food supplies, requiring the development of ...
Lionel Nicolas, Emilia Hilz, Stephanie Gamet, Vincent Thomas, Stephane Peyrard, Luigi Di Vietro, Benedicte Cirer, Julie Geist, Bernd Essigmann, Anne Ferry, Angeline Chanel, Frédéric Berniaud, Dominik Schwarz, Virginie Lempereur   +13 more
wiley   +1 more source

Detection of resistance in Phytophthora infestans to the carboxylic acid amide (CAA) fungicides using digital droplet PCR

Pest Management Science, Volume 81, Issue 10, Page 6295-6302, October 2025.
A ddPCR was developed to allow for the detection of the CAA resistance allele G1105S in Phytophthora infestans. The assay has been validated using DNA extracted from pure cultures and FTA cards, which are the principal means through which P. infestans is genotyped.
Amanpreet Kaur, Ewen Mullins, Steven Kildea   +2 more
wiley   +1 more source

Palladium-Catalyzed Decarbonylative C-H Difluoromethylation of Azoles. [PDF]

Org Lett
Gu F, Lalloo N, Wearing ER, Sanford MS.
europepmc   +1 more source

Mechanisms of resistance to azole antifungals.

, 1995
Patrick Marichal, H. Vanden Bossche
openalex   +1 more source

Phospholipid and sterol analysis of plasma membranes of azole-resistantCandida albicansstrains [PDF]

, 2000
Jà ⁄ rgen Löffler, H. Einsele, Holger Hebart, Ulrike Schumacher, Claudia Hrastnik, Gà ⁄ nther Daum   +5 more
openalex   +1 more source

Study Design and Rationale for The Breathe Easier With Tadalafil Therapy for Exercise‐Related Dyspnea in COPD‐PH (BETTER COPD‐PH)

Pulmonary Circulation, Volume 15, Issue 4, October 2025.
ABSTRACT Dyspnea, a debilitating symptom of COPD, worsens health‐related quality of life (HRQL), reduces daily physical activity, increases health care utilization, and is more closely associated with survival than airflow limitation. Thus, having treatments that reduce dyspnea in COPD is important.
Elena DeSanti, Matthew Jankowich, Gaurav Choudhary, Alan Morrison, Zachary K. Stanley, Eric Garshick, Marilyn L. Moy, Mohleen Kang, Cherry Wongtrakool, Ruxana T. Sadikot, Edward C. Dempsey, Matthew Griffith, Duc M. Ha, Christopher H. Schmid, Ronald H. Goldstein, Sharon Rounds, the BETTER COPD‐PH Study Group, Jayashri Aragam, Brack Hattler, Tim Lahm, Kristin L. Bailey, Debra Romberger, Gautam Kumar, Joshua Detelich, Jussi Saukkonen, Emily Wan, Shelsey Johnson, Malisa Barber, Christopher Halladay, Kathleen LaCerda, Renee LeClaire, Alexis Thavenet, Makkawi Makkawi, Mehret Tekle, Susan Burbach, Jenna Eggert, Julia Gillotti, Sridhar Tanukonda, Tiffany Elliott, Radhika Mungara, Matthew Lejy   +40 more
wiley   +1 more source