Results 31 to 40 of about 22,992 (261)
Challenges in Ramularia collo-cygni Control
Ramularia leaf spot (RLS), caused by the fungus Ramularia collo-cygni, has recently become widespread in Europe. Succinate dehydrogenase inhibitor (SDHI) and demethylation inhibitor (DMI) fungicides are mainly applied for disease control on barley fields,
Andres Mäe, Riinu Kiiker
doaj +1 more source
CAQ Corner: Basic concepts of transplant immunology
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Antifungal Drug Plasma Exposures: A Possible Contribution of Vitamin D-Related Gene Variants
Vitamin D (VD) seems to influence drug clearance and outcome. Antifungal drugs (AFU) are the most used azoles in clinical practice. In the literature, no data are available concerning VD’s impact on AFU therapy. The aim of this study was to analyze if VD
Jessica Cusato+12 more
doaj +1 more source
Antifungal prophylaxis with azole derivatives [PDF]
In recent years, several reports have underlined the increasing role of fungal infections as a cause of morbidity and mortality in hospitalised patients. For this reason, and also in light of the high mortality rate associated with these infections, chemoprophylaxis has been advocated by several authors.
CASTAGNOLA E+3 more
openaire +4 more sources
Antifungal azoles inhibit ergosterol biosynthesis by interfering with lanosterol 14α-demethylase. In this study, 7 upregulated and 4 downregulated ergosterol biosynthesis genes in response to ketoconazole treatment were identified in Neurospora crassa ...
Xianyun eSun+7 more
doaj +1 more source
Antifungal Resistance in Clinical Isolates of Candida glabrata in Ibero-America
In different regions worldwide, there exists an intra-and inter-regional variability in the rates of resistance to antifungal agents in Candida glabrata, highlighting the importance of understanding the epidemiology and antifungal susceptibility profiles
Erick Martínez-Herrera+6 more
doaj +1 more source
Evaluation of ERG-11 gene expression in azole resistant Candida isolates from various clinical specimens in ICUs [PDF]
Background: Candida infection is considered one of the most dangerous infections in intensive care unit patients (ICU). Resistance to azoles is a major challenging condition in treating candida infections.
Esraa Mohamed+2 more
doaj +1 more source
Population Pharmacokinetic Study of Tacrolimus in Pediatric Patients with Primary Nephrotic Syndrome: A Comparison of Linear and Nonlinear Michaelis Menten Pharmacokinetic Model [PDF]
Background Little is known about the population pharmacokinetics (PPK) of tacrolimus (TAC) in pediatric primary nephrotic syndrome (PNS). This study aimed to compare the predictive performance between nonlinear and linear PK models and investigate the significant factors of TAC PK characteristics in pediatric PNS.
arxiv +1 more source
The enantiomeric separation of antifungal compounds is an arduous task in pharmaceutical and biomedical fields due to the different properties that each diastereoisomer presents.
Laura Toribio+5 more
doaj +1 more source
New Antifungal Agents with Azole Moieties
Fungal conditions affect a multitude of people worldwide, leading to increased hospitalization and mortality rates, and the need for novel antifungals is emerging with the rise of resistance and immunocompromised patients.
Melissa Martins Teixeira+3 more
doaj +1 more source