Results 31 to 40 of about 17,549 (193)
AntibioticsBackground/Objectives: The diminished efficacy of azoles in treating fungal infections is attributed to the emergence of resistance among pathogenic fungi. Employing a synergistic approach with other compounds to enhance the antifungal activity of azoles
Sijin Hang +7 more
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Frontiers in Microbiology, 2013 Antifungal azoles inhibit ergosterol biosynthesis by interfering with lanosterol 14α-demethylase. In this study, 7 upregulated and 4 downregulated ergosterol biosynthesis genes in response to ketoconazole treatment were identified in Neurospora crassa ...
Xianyun eSun +7 more
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, 2014 Capítulo cuarto del temario del segundo bloque de la asignatura Ampliación de Química Orgánica Avanzada. Azoles.
Raoul Herbrecht, Yasmine Nivoix
openaire +3 more sources
New Antifungal Agents with Azole Moieties
Pharmaceuticals, 2022 Fungal conditions affect a multitude of people worldwide, leading to increased hospitalization and mortality rates, and the need for novel antifungals is emerging with the rise of resistance and immunocompromised patients.
Melissa Martins Teixeira +3 more
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LAM Genes Contribute to Environmental Stress Tolerance but Sensibilize Yeast Cells to Azoles
Frontiers in Microbiology, 2020 Lam proteins transport sterols between the membranes of different cellular compartments. In Saccharomyces cerevisiae, the LAM gene family consists of three pairs of paralogs.
Svyatoslav S. Sokolov +11 more
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European Journal of Clinical Microbiology & Infectious Diseases, 1997 Resistance of Candida to azoles is an increasing problem. Susceptibility testing of Candida against fluconazole and ketoconazole is now feasible and desirable. Good correlation of resistance in vitro with clinical failure of fluconazole therapy has now been shown in mucosal candidiasis.
Denning, D.W., Baily, G.G., Hood, S.V.
openaire +4 more sources
Chemistry – A European Journal, EarlyView.Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley +1 more source
Chemistry – A European Journal, EarlyView.A layered amino acid–based coordination polymer, (Zn(Leu)2), acts as a support that immobilizes diverse basic salts. The resulting solid sorbents remain nondeliquescent under humid, DAC‐relevant feeds while enabling CO2 capture. The interlayer‐immobilized sorbents exhibit high oxidative stability after accelerated oxidative aging, unlike conventional ...
Yuki Kohno, Takuji Ikeda, Takashi Makino
wiley +1 more source
Exploration, EarlyView.We designed and synthesized a dual‐type AIE photosensitizer (named TB) spray, containing a cationic quaternary ammonium unit and a glycosyl‐targeted boronic acid moiety, characterized for the elimination of biofilm infections of Candidozyma auris (C. auris) on high‐touch surfaces.
Xiaoyu Xu +16 more
wiley +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 BackgroundCryptococcosis is a global invasive mycosis with high rates of morbidity and mortality, especially in AIDS patients. Its treatment remains challenging because of the limited antifungals and their unavoidable toxicity, and as such more efforts ...
Yali Li +4 more
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