Results 31 to 40 of about 22,992 (261)

Challenges in Ramularia collo-cygni Control

open access: yesEncyclopedia, 2022
Ramularia leaf spot (RLS), caused by the fungus Ramularia collo-cygni, has recently become widespread in Europe. Succinate dehydrogenase inhibitor (SDHI) and demethylation inhibitor (DMI) fungicides are mainly applied for disease control on barley fields,
Andres Mäe, Riinu Kiiker
doaj   +1 more source

CAQ Corner: Basic concepts of transplant immunology

open access: yes, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Antifungal Drug Plasma Exposures: A Possible Contribution of Vitamin D-Related Gene Variants

open access: yesPharmaceuticals, 2022
Vitamin D (VD) seems to influence drug clearance and outcome. Antifungal drugs (AFU) are the most used azoles in clinical practice. In the literature, no data are available concerning VD’s impact on AFU therapy. The aim of this study was to analyze if VD
Jessica Cusato   +12 more
doaj   +1 more source

Antifungal prophylaxis with azole derivatives [PDF]

open access: yesClinical Microbiology and Infection, 2004
In recent years, several reports have underlined the increasing role of fungal infections as a cause of morbidity and mortality in hospitalised patients. For this reason, and also in light of the high mortality rate associated with these infections, chemoprophylaxis has been advocated by several authors.
CASTAGNOLA E   +3 more
openaire   +4 more sources

Sterol C-22 desaturase ERG5 mediates the sensitivity to antifungal azoles in Neurospora crassa and Fusarium verticillioides

open access: yesFrontiers in Microbiology, 2013
Antifungal azoles inhibit ergosterol biosynthesis by interfering with lanosterol 14α-demethylase. In this study, 7 upregulated and 4 downregulated ergosterol biosynthesis genes in response to ketoconazole treatment were identified in Neurospora crassa ...
Xianyun eSun   +7 more
doaj   +1 more source

Antifungal Resistance in Clinical Isolates of Candida glabrata in Ibero-America

open access: yesJournal of Fungi, 2021
In different regions worldwide, there exists an intra-and inter-regional variability in the rates of resistance to antifungal agents in Candida glabrata, highlighting the importance of understanding the epidemiology and antifungal susceptibility profiles
Erick Martínez-Herrera   +6 more
doaj   +1 more source

Evaluation of ERG-11 gene expression in azole resistant Candida isolates from various clinical specimens in ICUs [PDF]

open access: yesMicrobes and Infectious Diseases, 2022
Background: Candida infection is considered one of the most dangerous infections in intensive care unit patients (ICU). Resistance to azoles is a major challenging condition in treating candida infections.
Esraa Mohamed   +2 more
doaj   +1 more source

Population Pharmacokinetic Study of Tacrolimus in Pediatric Patients with Primary Nephrotic Syndrome: A Comparison of Linear and Nonlinear Michaelis Menten Pharmacokinetic Model [PDF]

open access: yesEur J Pharm Sci. 2020 Feb 15;143:105199, 2019
Background Little is known about the population pharmacokinetics (PPK) of tacrolimus (TAC) in pediatric primary nephrotic syndrome (PNS). This study aimed to compare the predictive performance between nonlinear and linear PK models and investigate the significant factors of TAC PK characteristics in pediatric PNS.
arxiv   +1 more source

Study of Different Chiral Columns for the Enantiomeric Separation of Azoles Using Supercritical Fluid Chromatography

open access: yesSeparations, 2022
The enantiomeric separation of antifungal compounds is an arduous task in pharmaceutical and biomedical fields due to the different properties that each diastereoisomer presents.
Laura Toribio   +5 more
doaj   +1 more source

New Antifungal Agents with Azole Moieties

open access: yesPharmaceuticals, 2022
Fungal conditions affect a multitude of people worldwide, leading to increased hospitalization and mortality rates, and the need for novel antifungals is emerging with the rise of resistance and immunocompromised patients.
Melissa Martins Teixeira   +3 more
doaj   +1 more source

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