Antifungal Drug Plasma Exposures: A Possible Contribution of Vitamin D-Related Gene Variants
Pharmaceuticals, 2022 Vitamin D (VD) seems to influence drug clearance and outcome. Antifungal drugs (AFU) are the most used azoles in clinical practice. In the literature, no data are available concerning VD’s impact on AFU therapy. The aim of this study was to analyze if VD
Jessica Cusato +12 more
doaj +1 more source
Bloodstream yeast infections: a 15-month survey [PDF]
, 2009 A 15-month survey of 412 bloodstream yeast isolates from 54 Belgian hospitals was undertaken. Candida albicans was the most common species (47.3%) followed by C. glabrata (25.7%), C. parapsilosis (8.0%), C. tropicalis (6.8%) and Saccharomyces cerevisiae (
Detandt, M +3 more
core +1 more source
Predictive, Data‐Driven Design of Red‐Light Photoredox Catalysts for C─Heteroatom Bond Formation
Angewandte Chemie, EarlyView.From redox numbers to red light: Donor oxidation and core reduction potentials predict E0‐0 in cyanoarene dyes, guiding selection of an efficient red‐light catalyst, 4MeODPATPN (PC13). Under 620 nm light, PC13 facilitates Ni‐catalyzed C─heteroatom cross‐couplings (C─N, C─O, C─S) with high functional‐group tolerance and reduced hydrodehalogenation ...
Amir Gizatullin +6 more
wiley +2 more sources
Trichosporon asahii Infective Endocarditis of Prosthetic Valve: A Case Report and Literature Review
Antibiotics, 2023 Trichosporon spp. endocarditis is a severe and hard-to-treat infection. Immunosuppressed subjects and carriers of prosthetic valves or intracardiac devices are at risk.
Alice Mulè +13 more
doaj +1 more source
Evaluation of Antibacterial and Anticandidal Activities of Some Imidazole, Benzimidazole and Benztriazole Derivatives [PDF]
Trends in Pharmaceutical Sciences, 2022 In recent years, resistance to conventional antimicrobial drugs has become a serious concern in the clinic. Hence, the discovery of novel and effective antimicrobial agents with improved properties is of great value.
Sara Sadeghian +6 more
doaj +1 more source
Sensitivity towards DMI fungicides and haplotypic diversity of their CYP51 target in the Mycosphaerella graminicola population of Flanders [PDF]
, 2014 Septoria leaf blotch, caused by the fungus Mycosphaerella graminicola, is the most important wheat disease in Northwestern Europe, and is currently controlled by fungicide applications.
Curvers, Katrien +4 more
core +1 more source
Intensive care unit-related fluconazole use in Spain and Germany: patient characteristics and outcomes of a prospective multicenter longitudinal observational study [PDF]
, 2013 Background: Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. Objective: To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany ...
Ballus, Jose +7 more
core +1 more source
Nuclear Quadrupole Resonance Spectroscopy: Tautomerism and Structure of Functional Azoles
Crystals, 2019 The Nuclear Quadrupole Resonance spectroscopy data of functionalized azoles (imidazoles, triazoles and corresponding benzazoles) are reviewed and critically discussed. The possibility of studying the tautomerism of azoles by the NQR method is considered.
Lyudmila I. Larina
doaj +1 more source
New Antifungal Agents with Azole Moieties
Pharmaceuticals, 2022 Fungal conditions affect a multitude of people worldwide, leading to increased hospitalization and mortality rates, and the need for novel antifungals is emerging with the rise of resistance and immunocompromised patients.
Melissa Martins Teixeira +3 more
doaj +1 more source
Exploring hidden dimensions of soil fungal biodiversity: A simple technique to detect soil fungi resistant to antifungal compounds [PDF]
, 2010 Soils are known to be ultimate and complex reservoirs of microbial diversity. The complex dimensions of bacterial and fungal diversity in tropical soils and microbial community dynamics are underexplored.
Nandkumar M. Kamat +1 more
core +2 more sources