Results 41 to 50 of about 22,992 (261)
An aptamer-biosensor for azole class antifungal drugs [PDF]
, 2017 This report describes the development of an aptamer for sensing azole antifungal drugs for therapeutic drug monitoring. Modified Synthetic Evolution of Ligands through Exponential Enrichment (SELEX) was used to discover a DNA aptamer recognizing azole class antifungal drugs.
arxiv +1 more source
Journal of Fungi, 2021 Azoles are one of the most widely used drugs to treat fungal infections. To further understand the fungal response to azoles, we analyzed the MAPK circuitry of the model yeast Saccharomyces cerevisiae that operates under treatment with these antifungals.
Ángela Sellers-Moya +3 more
doaj +1 more source
Pharmacokinetic drug interactions of azoles [PDF]
Current Fungal Infection Reports, 2008 Drug-drug interactions are a major concern with triazoles. Azoles are potent metabolic inhibitors and interactions commonly occur via metabolizing enzymes (ie, cytochrome P450 isoenzyme superfamily) or drug transporters (ie, P-glycoprotein). However, the clinical relevance of these interactions may vary upon the azole involved and upon the “target ...
Bruggemann, R.J.M. +6 more
openaire +4 more sources
Journal of Fungi, 2021 Numerous reports describe the emergence of resistance in dermatophytes, especially in T. rubrum and T. mentagrophytes/indotineae strains. We here present a review of the current status of resistance in dermatophytes worldwide.
Rosalie Sacheli, Marie-Pierre Hayette
doaj +1 more source
Alcohol-Based Adsorption Heat Pumps using Hydrophobic Metal-Organic Frameworks [PDF]
arXiv, 2023 The building climate industry and its influence on energy consumption have consequences on the environment due to the emission of greenhouse gasses. Improving the efficiency of this sector is essential to reduce the effect on climate change. In recent years, the interest in porous materials in applications such as heat pumps has increased for their ...
arxiv
Emerging Trends in the Use of Topical Antifungal-Corticosteroid Combinations
Journal of Fungi, 2022 A broad range of topical antifungal formulations containing miconazole or terbinafine as actives are commonly used as efficacious choices for combating fungal skin infections.
Dalibor Mijaljica +2 more
doaj +1 more source
DFT investigations on arylsulphonyl pyrazole derivatives as potential ligands of selected kinases
Open Chemistry, 2020 Using the density functional theory (DFT) formalism, we have investigated the properties of some arylsulphonyl indazole derivatives that we studied previously for their biological activity and susceptibility to interactions of azoles. This study includes
Czaja Kornelia +3 more
doaj +1 more source
Emergence and Genomic Characterization of Multidrug Resistant Candida auris in Nigeria, West Africa
Journal of Fungi, 2022 Candida auris is an emerging multidrug-resistant fungal pathogen that has become a worldwide public health threat due to the limitations of treatment options, difficulty in diagnosis, and its potential for clonal transmission.
Rita Oladele +5 more
doaj +1 more source
Frontiers in Microbiology, 2018 Objectives: Invasive mold infections associated with Aspergillus species are a significant cause of mortality in immunocompromised patients. The most frequently occurring aetiological pathogens are members of the Aspergillus section Fumigati followed by ...
Tamara Zoran +53 more
doaj +1 more source
Computational Simulations of Metal–Organic Frameworks to Enhance Adsorption Applications
Advanced Materials, EarlyView.This review highlights the significance of molecular simulations in expanding the understanding of metal–organic frameworks (MOFs) and improving their gas adsorption applications. The historical development and implementation of molecular simulations in the MOF field are given, high‐throughput computational screening studies used to unlock the ...
Hilal Daglar +3 more
wiley +1 more source