Results 51 to 60 of about 40,795 (299)
Angewandte Chemie, EarlyView.A general strategy has been developed for predictable and robust vinyl halide cross‐coupling reactions. This approach demonstrates broad applicability across seven distinct bond‐forming transformations, featuring wide electrophile and nucleophile scope, high tolerance for functional groups, and suitability for late‐stage functionalization of complex ...
Kousik Das +4 more
wiley +2 more sources
Antifungal Drug Plasma Exposures: A Possible Contribution of Vitamin D-Related Gene Variants
Pharmaceuticals, 2022 Vitamin D (VD) seems to influence drug clearance and outcome. Antifungal drugs (AFU) are the most used azoles in clinical practice. In the literature, no data are available concerning VD’s impact on AFU therapy. The aim of this study was to analyze if VD
Jessica Cusato +12 more
doaj +1 more source
In vitro biofilms and antifungal susceptibility of dermatophyte and non-dermatophyte moulds involved in foot mycosis [PDF]
, 2017 Tinea pedis and onychomycosis are among the commonest fungal diseases in the world. Dermatophytes and, less frequently, non-dermatophyte moulds are aetiological agents of foot mycosis and are capable of forming biofilms.
Bougnoux, Marie Élisabeth +5 more
core +1 more source
Angewandte Chemie, EarlyView.An electrochemical α‐C─H functionalization of nitramines enables the synthesis of molecules containing bifunctional energetic heterocycles with promising properties. A telescoped, HNO3‐free sequence involving nitration and azolation steps offers a safer, modular, and scalable platform for the synthesis of energetic compounds.
Wan‐Chen Cindy Lee +4 more
wiley +2 more sources
New strategic insights into managing fungal biofilms [PDF]
, 2015 Fungal infections have dramatically increased in the last decades in parallel with an increase of populations with impaired immunity, resulting from medical conditions such as cancer, transplantation or other chronic diseases.
Borghi, Elisa +6 more
core +4 more sources
Pharmacokinetic drug interactions of azoles [PDF]
Current Fungal Infection Reports, 2008 Drug-drug interactions are a major concern with triazoles. Azoles are potent metabolic inhibitors and interactions commonly occur via metabolizing enzymes (ie, cytochrome P450 isoenzyme superfamily) or drug transporters (ie, P-glycoprotein). However, the clinical relevance of these interactions may vary upon the azole involved and upon the “target ...
Bruggemann, R.J.M. +6 more
openaire +4 more sources
Trichosporon asahii Infective Endocarditis of Prosthetic Valve: A Case Report and Literature Review
Antibiotics, 2023 Trichosporon spp. endocarditis is a severe and hard-to-treat infection. Immunosuppressed subjects and carriers of prosthetic valves or intracardiac devices are at risk.
Alice Mulè +13 more
doaj +1 more source
Computational Simulations of Metal–Organic Frameworks to Enhance Adsorption Applications
Advanced Materials, EarlyView.This review highlights the significance of molecular simulations in expanding the understanding of metal–organic frameworks (MOFs) and improving their gas adsorption applications. The historical development and implementation of molecular simulations in the MOF field are given, high‐throughput computational screening studies used to unlock the ...
Hilal Daglar +3 more
wiley +1 more source
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Old World cutaneous leishmaniasis treatment response varies depending on parasite species, geographical location and development of secondary infection [PDF]
, 2019 Background: In the Kingdom of Saudi Arabia (KSA), Leishmania major and L. tropica are the main causative agents of Old World cutaneous leishmaniasis (CL).
Acosta-Serrano, Álvaro +16 more
core +9 more sources