Results 61 to 70 of about 34,737 (245)

Pesticide Contamination in the Hair of Children From Colonia San Juan, a Rural Community in Paraguay

Drug Testing and Analysis, EarlyView.
Hair analysis in children from a rural community in Paraguay reveals exposure to organophosphates, pyrethroids, neonicotinoids, fungicides, herbicides, and endocrine disruptors, highlighting the urgent need for stricter environmental protections and preventive health measures. ABSTRACT Chronic exposure to pesticides can cause carcinogenic, reproductive,
Stela Benitez Leite, Alba Iglesias‐Gonzalez, Mirta Noemí Mesquita, María Luisa Macchi, Robin Mesnage, Brice M. R. Appenzeller   +5 more
wiley   +1 more source

Study of Different Chiral Columns for the Enantiomeric Separation of Azoles Using Supercritical Fluid Chromatography

Separations, 2022
The enantiomeric separation of antifungal compounds is an arduous task in pharmaceutical and biomedical fields due to the different properties that each diastereoisomer presents.
Laura Toribio, Irene Magdaleno, Beatriz Martín-Gómez, María T. Martín, Silvia Valverde, Ana M. Ares   +5 more
doaj   +1 more source

Toxicity prediction of anti tuberculosis active molecules [PDF]

, 2011
The aim of the work was to understand the toxicity, physically significant descriptors and pharmaceutically relevant properties of some imidazoles obtained from the open sources that may found to be active against tuberculosis.
Abdul Jaleel.U.C, Sajeev R
core   +2 more sources

Aggregation‐induced emission luminogens in in vitro diagnostics: Advancing biomarker detection in body fluids

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes recent advances in aggregation‐induced emission (AIE) materials for in vitro diagnostics (IVD). It highlights probe design strategies—categorizing them into direct‐responsive, indirect‐responsive, and nano‐immunoprobes—and their applications in detecting a wide range of biomarkers across diverse body fluids ...
Qi Liu, Xirui Chen, Kenian Wang, Yifan Wu, Xiangcai Zou, Ying Li   +5 more
wiley   +1 more source

Synergistic Anti-Candida Activity of Bengazole A in the Presence of Bengamide A †. [PDF]

, 2019
Bengazoles A⁻G from the marine sponge Jaspis sp. exhibit potent in vitro antifungal activity against Candida spp. and other pathogenic fungi. The mechanism of action (MOA) of bengazole A was explored in Candida albicans under both liquid culture and ...
Cheng, Tina, Jamison, Matthew T, Molinski, Tadeusz F, Wang, Xiao   +3 more
core  

Adsorption of imidazole on Au(111) surface: Dispersion corrected density functional study [PDF]

, 2016
We use density functional theory in the generalized gradient approximation to study the adsorption of imidazole on the Au(111) surface and account for dispersion effect using Grimme's empirical dispersion correction technique.
Abou El Makarim, Hassna, Benoit, David M., Izzaouihda, Safia, Komiha, Najia, Mahjoubi, Khaled   +4 more
core   +1 more source

Model Informed Precision Dosing of Tacrolimus in Children Following Heart Transplant

The Journal of Clinical Pharmacology, EarlyView.
Abstract Tacrolimus is a first‐line immunosuppressant used after solid organ transplantation that suffers from extensive intra‐ and inter‐patient variability and a narrow therapeutic window. Its critical role in a fragile population, coupled with the difficulties identifying and maintaining an appropriate dose within a given patient, make it an ideal ...
Jadon S. Wagstaff, Shaun S. Kumar, Kimberly M. Molina, Joseph E. Rower   +3 more
wiley   +1 more source

NMR‐Based Structural Analysis of Highly Substituted Pyridines From Kondrat'eva Aza‐Diels–Alder Cycloadditions

Magnetic Resonance in Chemistry, EarlyView.
We report the results from a kinetic and mechanistic investigation of an inverse‐electron‐demand Diels–Alder (IEDDA) cycloaddition involving an oxazole‐type diene synthesized via an Ugi–Zhu multicomponent reaction (UZ‐3CR). ABSTRACT Pyridines are a crucial class of heterocycles with widespread applications in natural products, pharmaceuticals, and ...
Galdina V. Suárez‐Moreno, Francisco Méndez, Atilano Gutierrez‐Carrillo, Mónica A. Rincón‐Guevara, Yoarhy A. Amador‐Sánchez, Alejandro Islas‐Jácome, Eduardo González‐Zamora   +6 more
wiley   +1 more source

Development of cross-resistance by Aspergillus fumigatus to clinical azoles following exposure to prochloraz, an agricultural azole [PDF]

, 2014
Background: The purpose of this study was to unveil whether azole antifungals used in agriculture, similar to the clinical azoles used in humans, can evoke resistance among relevant human pathogens like Aspergillus fumigatus, an ubiquitous agent in ...
Estevinho, Leticia M., Faria-Ramos, Isabel, Farinha, Sofia, Miranda, Isabel M., Neves-Maia, João, Pina-Vaz, Cidália, Rodrigues, Acácio G., Tavares, Pedro R.   +7 more
core   +1 more source

Corrosion Inhibition Mechanism and Stability of Quinic Acid as a Green Corrosion Inhibitor on Mild Steel

ChemistryOpen, EarlyView.
It has been found that quinic acid, an organic acid found in various plants, exhibits a high level of corrosion inhibition activity in preventing HCl‐induced corrosion and maintains its stability up to 144 h. Environmentally friendly quinic acid has a high potential for use as corrosion inhibitors in mild steel.
Serap Toprak Döşlü, Leyla ERCAN
wiley   +1 more source