Results 71 to 80 of about 40,795 (299)

Linezolid in Combination With Azoles Induced Synergistic Effects Against Candida albicans and Protected Galleria mellonella Against Experimental Candidiasis

open access: yesFrontiers in Microbiology, 2019
The incidence of resistant Candida isolates has increased continuously in recent decades, especially Candida albicans. To overcome this resistance, research on antifungal sensitizers has attracted considerable attention.
Mengjiao Lu   +7 more
doaj   +1 more source

Emergence and Genomic Characterization of Multidrug Resistant Candida auris in Nigeria, West Africa

open access: yesJournal of Fungi, 2022
Candida auris is an emerging multidrug-resistant fungal pathogen that has become a worldwide public health threat due to the limitations of treatment options, difficulty in diagnosis, and its potential for clonal transmission.
Rita Oladele   +5 more
doaj   +1 more source

The Structure of Nitro‐ and Polynitropyrazoles: X‐Ray Crystallography Versus Theoretical Calculations

open access: yesAsian Journal of Organic Chemistry, EarlyView.
Abstract This publication presents the geometries of 157 nitro‐ and polynitropyrazoles. Among these, 109 compounds were theoretically studied using mainly the B3LYP/6–311++G(d,p) level of theory. Three‐parameter Lee‐Yang‐Parr (B3LYP) is a density functional theory (DFT) method widely used in computational chemistry and constitutes an acceptable ...
Rosa M. Claramunt   +3 more
wiley   +1 more source

Emerging Trends in the Use of Topical Antifungal-Corticosteroid Combinations

open access: yesJournal of Fungi, 2022
A broad range of topical antifungal formulations containing miconazole or terbinafine as actives are commonly used as efficacious choices for combating fungal skin infections.
Dalibor Mijaljica   +2 more
doaj   +1 more source

Synergistic Anti-Candida Activity of Bengazole A in the Presence of Bengamide A †. [PDF]

open access: yes, 2019
Bengazoles A⁻G from the marine sponge Jaspis sp. exhibit potent in vitro antifungal activity against Candida spp. and other pathogenic fungi. The mechanism of action (MOA) of bengazole A was explored in Candida albicans under both liquid culture and ...
Cheng, Tina   +3 more
core  

Fungal biofilm resistance [PDF]

open access: yes, 2012
Fungal biofilm infections have become increasingly recognised as a significant clinical problem. One of the major reasons behind this is the impact that these have upon treatment, as antifungal therapy often fails and surgical intervention is required ...
Rajendran, Ranjith   +3 more
core   +4 more sources

History of the development of azole derivatives [PDF]

open access: yesClinical Microbiology and Infection, 2004
Until the 1940s, relatively few agents were available for the treatment of systemic fungal infections. The development of the polyene antifungals represented a major advance in medical mycology. Although amphotericin B quickly became the mainstay of therapy for serious infections, its use was associated with infusion-related side-effects and dose ...
openaire   +3 more sources

Grenzflächen‐Photoelektrochemie in der Organischen Synthese

open access: yesAngewandte Chemie, EarlyView.
Heterogene Photoelektroden sind für die Aktivierung von H2O und CO2 weit verbreitet, während homogene Photoelektrochemie mit molekularen Katalysatoren die Aktivierung komplexer Moleküle in der Synthese dominiert. Dennoch bietet Grenzflächen‐Photoelektrochemie (iPEC) ein großes Potenzial für die Synthese, einschließlich Kosteneffizienz ...
Gabriel Chan   +4 more
wiley   +1 more source

Toxicity prediction of anti tuberculosis active molecules [PDF]

open access: yes, 2011
The aim of the work was to understand the toxicity, physically significant descriptors and pharmaceutically relevant properties of some imidazoles obtained from the open sources that may found to be active against tuberculosis.
Abdul Jaleel.U.C, Sajeev R
core   +2 more sources

The role of azoles in the management of azole-resistant aspergillosis: From the bench to the bedside

open access: yesDrug Resistance Updates, 2014
Azole resistance is an emerging problem in Aspergillus fumigatus and is associated with a high probability of treatment failure. An azole resistance mechanism typically decreases the activity of multiple azole compounds, depending on the mutation. As alternative treatment options are limited and in some isolates the minimum inhibitory concentration ...
Seyedmousavi, S.   +4 more
openaire   +4 more sources

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