Results 71 to 80 of about 22,992 (261)
BMC Microbiology, 2022 Background This study was aimed to determine the potency of Minocycline (MIN) and azoles, including itraconazole (ITR), voriconazole (VOR) and posaconazole (POS) against Scedosporium and Lomentospora species.
Fang Yang, Yi Sun, Qiaoyun Lu
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High-Pressure Synthesis of a Pentazolate Salt [PDF]
arXiv, 2016 The pentazolates, the last all-nitrogen members of the azole series, have been notoriously elusive for the last hundred years despite enormous efforts to make these compounds in either gas or condensed phases. Here we report a successful synthesis of a solid state compound consisting of isolated pentazolate anions N5-, which is achieved by compressing ...
arxiv
ChemMedChem, Accepted Article.Although great progresses have been accomplished in the field of antineoplastic treatments, the need for chemotherapy agents with new mechanisms of action remains essential. Metal complexes presenting hemilabile ligands could combine structural toxicity upon full coordination of the ligand and reactive toxicity upon ligand partial decoordination ...
Tom Lacoma +6 more
wiley +1 more source
Low‐Energy Electron‐Induced Dissociation of the Radiosensitizing Agent Sanazole
ChemPlusChem, EarlyView.Employing mass spectrometry supported by quantum chemical calculations, electron attachment to gas‐phase and microhydrated sanazole, a hypoxic radiosensitizer, is examined. The results suggest that hydration closes and/or slows down the dissociation process and indicates that the initial mechanism of action in a reductive cell environment may be ...
Farhad Izadi +5 more
wiley +1 more source
American International Journal of Biology and Life Sciences, 2019 Azoles are one of a cyclic derivatives of chemical heterocyclic chemical and organic compounds including g a five member di unsaturated ring structure composed of bi nitrogen atoms at position (3 and 4) and one sulfur atom at position (1). Most of prepared work
openaire +2 more sources
Pharmacists' views on the implementation of therapeutic drug monitoring in oncology
Journal of Pharmacy Practice and Research, EarlyView.Abstract Background There is increasing interest in the potential benefit of therapeutic drug monitoring (TDM) in oncology. However, uptake in Australian hospitals is limited. Aim This study sought to explore hospital pharmacists' experiences with TDM in oncology, seeking to determine if they could provide insights into barriers and facilitators to its
Jane E. Carland +3 more
wiley +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background Atopic dermatitis (AD) is characterised by immune dysregulation and skin‐barrier dysfunction, which can predispose to microbial dysbiosis and skin infections. Fungi, particularly Malassezia, are common skin colonisers in AD patients and may exacerbate the condition.
Luis F. Andrade +8 more
wiley +1 more source
ChemistryOpen, EarlyView.Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas +4 more
wiley +1 more source
ChemistryOpen, EarlyView.A series of azomethine‐pyrazole derivatives bearing a para‐substituted azo‐phenyl ring is straightforwardly prepared. The new compounds display an elevated antifungal activity against various Candida species and Cryptococcus neoformans strains. DFT and molecular docking calculations are used to determine possible routes of action through interactions ...
María Isabel Murillo +8 more
wiley +1 more source
A Review of Antifungals and their Mono- and Combination- therapy in the Treatment of Invasive Fungal Infections [PDF]
Journal of Kerman University of Medical Sciences, 2016 Invasive fungal infections with high mortality rate are a growing health concern in hospitals and medical centers. The infection usually occurs in people with compromised immune systems.
Amir Arastefar, Parisa Badiee
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