Results 81 to 90 of about 40,795 (299)
Frontiers in Microbiology, 2018 Objectives: Invasive mold infections associated with Aspergillus species are a significant cause of mortality in immunocompromised patients. The most frequently occurring aetiological pathogens are members of the Aspergillus section Fumigati followed by ...
Tamara Zoran +53 more
doaj +1 more source
Benzotriazole is antiestrogenic in vitro but not in vivo [PDF]
, 2007 Copyright © 2007 SETAC. This is the accepted version of the following article: Harris et al (2007), "Benzotriazole is antiestrogenic in vitro but not in vivo", Environmental Toxicology and Chemistry, 26(11), 2367–2372, which has been published in final ...
Brian, JV +5 more
core +1 more source
Memorias do Instituto Oswaldo Cruz, 2012 Ketoconazole is a clinically safe antifungal agent that also inhibits the growth of Leishmania spp. A study was undertaken to determine whether Leishmania parasites are prone to becoming resistant to ketoconazole by upregulating C14-demethylase after ...
Valter Viana Andrade-Neto +5 more
doaj +1 more source
Development of cross-resistance by Aspergillus fumigatus to clinical azoles following exposure to prochloraz, an agricultural azole [PDF]
, 2014 Background: The purpose of this study was to unveil whether azole antifungals used in agriculture, similar to the clinical azoles used in humans, can evoke resistance among relevant human pathogens like Aspergillus fumigatus, an ubiquitous agent in ...
Estevinho, Leticia M. +7 more
core +1 more source
Untersuchungen über Azole [PDF]
Justus Liebigs Annalen der Chemie, 1889 n ...
openaire +2 more sources
Interfacial Photoelectrochemistry in Organic Synthesis
Angewandte Chemie International Edition, EarlyView.Heterogeneous photoelectrodes are widespread for activations of H2O and CO2, while homogeneous photoelectrochemistry with molecular catalysts dominates complex molecule activations in synthesis. Nonetheless, interfacial photoelectrochemistry (iPEC) offers great potential for synthesis, including catalyst cost‐efficiency, reusability, and stability ...
Gabriel Chan +4 more
wiley +1 more source
The Fungal CYP51s: Their Functions, Structures, Related Drug Resistance, and Inhibitors
Frontiers in Microbiology, 2019 CYP51 (Erg11) belongs to the cytochrome P450 monooxygenase (CYP) superfamily and mediates a crucial step of the synthesis of ergosterol, which is a fungal-specific sterol. It is also the target of azole drugs in clinical practice.
Jingxiang Zhang +8 more
doaj +1 more source
Electrochemical N-olefination for the regio- and stereo-selective synthesis of vinyl azoles
Green Synthesis and CatalysisA selenium-catalyzed electrosynthesis involving regio- and stereo-selective N-olefination of azoles was developed. The room-temperature reaction was efficient (up to 97 % yield) and compatible with various styrenes and azoles.
Kejun Lin +3 more
doaj +1 more source
Clinical Case Reports, 2019 Key Clinical Message We report the initiation of CFTR modulator lumacaftor/ivacaftor combination (LUM/IVA) in two adolescents with cystic fibrosis who were treated with antifungal azoles (AZO) and tacrolimus (TCS) for liver transplantation.
Ikrame Chouchane +2 more
doaj +1 more source
A Broadly Applicable Strategy to Aminate Azines Enabled by Electronically Tuned Phosphine Reagents
Angewandte Chemie International Edition, EarlyView.We have developed a pyridine C4‐amination reaction via phosphonium salt intermediates, where an electronically tuned phosphine is key to successful C─N bond formation. The process accommodates aliphatic amines, (heteroaryl)anilines, hydrazines, and nitrogen heteroaromatics, as well as a variety of pyridine building blocks and late‐stage C─N couplings ...
Ren‐Rong Liu +2 more
wiley +1 more source