Results 1 to 10 of about 30,808 (260)

Activation of p53 signaling and regression of breast and prostate carcinoma cells by spirooxindole-benzimidazole small molecules

Frontiers in Pharmacology
This study discusses the synthesis and use of a new library of spirooxindole-benzimidazole compounds as inhibitors of the signal transducer and activator of p53, a protein involved in regulating cell growth and cancer prevention.
Assem Barakat, Saeed Alshahrani, Abdullah Mohammed Al-Majid, Abdullah Saleh Alamary, Matti Haukka, Marwa M. Abu-Serie, Alexander Dömling, Luis R. Domingo, Yaseen A. M. M. Elshaier   +8 more
doaj   +1 more source

Novel Highly Functionalized Benzoylaminocarbothioyl Pyrrolidine from Benzoylisothiocyanate and Substitueted Pyrrolidine Derived From α-Aminoasit Ester via Imine -Azomethine Ylide- 1,3-Dipolar Cycloaddition Cascade [PDF]

, 2004
H. Ali Döndaş, Ozgul Altinbas
openalex   +1 more source

exo‐ and Enantioselective Cycloaddition of Azomethine Ylides Generated from N‐Alkylidene Glycine Esters Using Chiral Phosphine—Copper Complexes. [PDF]

, 2004
Yoji Oderaotoshi, Wenji Cheng, Shintaro Fujitomi, Yukihiro Kasano, Satoshi Minakata, Mitsuo Komatsu   +5 more
openalex   +1 more source

Synthesis, pharmacokinetics, and biological use of lysine-modified single-walled carbon nanotubes

International Journal of Nanomedicine, 2014
J Justin Mulvey,1,2 Evan N Feinberg,1,3 Simone Alidori,1 Michael R McDevitt,4,5 Daniel A Heller,1,6 David A Scheinberg1,5,6 1Molecular Pharmacology and Chemistry Program, Sloan Kettering Institute, New York, NY, USA; 2Tri-Institutional MD-PhD Program ...
Mulvey JJ, Feinberg EN, Alidori S, McDevitt MR, Heller DA, Scheinberg DA   +5 more
doaj  

Cu(I)‐Catalyzed Highly Exo‐Selective and Enantioselective [3 + 2] Cycloaddition of Azomethine Ylides with Acrylates. [PDF]

, 2005
Wenzhong Gao, Xumu Zhang, Malati Raghunath   +2 more
openalex   +1 more source

2,5-Di-tert-butyl-2,5-diethylpyrrolidine-1-oxyls: Where Is a Reasonable Limit of Sterical Loading for Higher Resistance to Reduction?

Molecules
The pyrrolidine nitroxides with four bulky alkyl substituents adjacent to the N–O∙ group demonstrate very high resistance to reduction with biogenic antioxidants and enzymatic systems.
Irina F. Zhurko, Sergey A. Dobrynin, Yurii I. Glazachev, Yuri V. Gatilov, Igor A. Kirilyuk   +4 more
doaj   +1 more source

A New Synthetic Method for Proline Derivatives via the Azomethine Ylide Intermediate Generated from Methyl N-(Trimethylsilylmethyl)iminoacetate

, 1985
Kazuo Achiwa, Nobuyuki Imai, Yoshiyasu Terao   +2 more
openalex   +1 more source

Intermolecular cycloaddition of nonstabilized azomethine ylides generated from 1,3-thiazolidine-4-carboxylic acids: synthesis of 5,7a-dihydro-1H,3H-pyrrolo[1,2-c]thiazoles [PDF]

, 2006
Ana L. Cardoso, Agnieszka Kaczor, Artur M. S. Silva, Rui Fausto, Teresa M. V. D. Pinho e Melo, Α. Μ. d’A. Rocha Gonsalves   +5 more
openalex   +1 more source

The [3+2] Intramolecular Cycloaddition Reaction of Azomethine Ylides Generated from Benzylic N-Oxides

, 1990
Georges Roussi
openalex   +1 more source

1,3-Dipolar Cycloadditoin Reaction of 2-[(Trimethylsilylmethylamino)(methylthio)]methylene-1,3-indandione: Synthetic Equivalent of Cyclic Dicarbonyl Alkylidene-azomethine Ylide as a Novel 1,3-Dipolar Reagent

, 1995
Yoshinori Tominaga, Satoshi Takada, Shinya Kahra   +2 more
openalex   +1 more source