Results 21 to 30 of about 27,751 (287)

New Conjugatable Platinum(II) Chlorins: Synthesis, Reactivity and Singlet Oxygen Generation [PDF]

Molecules
An efficient protocol was developed for the microwave-mediated metallation of 5-(4-methoxycarbonylphenyl)-10,15,20-tris(pentafluorophenyl)porphyrin (P1) with bis(benzonitrile)platinum dichloride salt and subsequent 1,3-dipolar cycloaddition of the ...
José Almeida, Giampaolo Barone, Luís Cunha-Silva, Ana F. R. Cerqueira, Augusto C. Tomé, Maria Rangel, Ana M. G. Silva   +6 more
doaj   +2 more sources

Fused Nitrogen Bridgehead N,O-Acetals as Versatile Scaffolds: Synthetic Strategies, Mechanism and Applications. [PDF]

Chemistry
Fused nitrogen‐bridgehead N,O‐acetals receive specific emphasis as pivotal scaffolds due to their significant role in the bioactivity of medicinally relevant molecules. Significant approaches have been reported on their role as key synthetic building blocks/motifs in the construction of complex organic molecules and their utility as chiral auxiliaries ...
Kouvelas AD, Kallitsakis MG, Lykakis IN.
europepmc   +2 more sources

<i>N</i>-Oxide Insertion into LDA Dimeric Aggregates for Azomethine Ylide Formation: Explicit Solvation in Quantum Mechanical Treatment of Polarized Intermediates. [PDF]

J Org Chem
Neal MJ, Chartier EJ, Lane AM, Hejnosz SL, Jesikiewicz LT, Liu P, Rohde JJ, Lummis P, Fox DJ, Evanseck JD, Montgomery TD.   +10 more
europepmc   +2 more sources

Synthesis of Novel Benzofuran Spiro-2-Pyrrolidine Derivatives via [3+2] Azomethine Ylide Cycloadditions and Their Antitumor Activity. [PDF]

Int J Mol Sci
Pan B, Wang T, Zheng L, Dong Z, Liu L, Liu X, Feng T, Zhou Y, Shi Y.   +8 more
europepmc   +2 more sources

Polar [3+2] cycloaddition between N-methyl azomethine ylide and trans-3,3,3-trichloro-1-nitroprop-1-ene

Scientiae Radices, 2022
Pyrrolidines are important heterocyclic organic compounds which show biological effects. Many of them are successfully used in medicine. These compounds can also be applied in industry, for example as dyes or agrochemical substances. Therefore, the study
Magdalena Żmigrodzka, Mikołaj Sadowski, Jowita Kras, Ewa Desler, O. Demchuk, Karolina Kula   +5 more
semanticscholar   +1 more source

Fully conjugated azacorannulene dimer as large diaza[80]fullerene fragment

Nature Communications, 2022
Heterofullerenes are an important synthetic target for organic chemists. Here, the authors demonstrate a fully conjugated azacorannulene dimer starting from a bifunctional polycyclic aromatic azomethine ylide, providing a powerful method for the bottom ...
Weifan Wang, Fiona Hanindita, Yosuke Hamamoto, Yongxin Li, Shingo Ito   +4 more
doaj   +1 more source

One-Step Maleimide-Based Dual Functionalization of Protein N-Termini. [PDF]

Angew Chem Int Ed Engl
Maleimides can target the N‐termini of proteins instead of cysteine by the use of 2‐pyridinecarboxaldehyde and copper(II) salt under non‐denaturing conditions. The methodology requires no mutagenesis of proteins and enables the high‐yield attachment of various functional groups to proteins with various N‐terminal amino acids through a simple operation ...
Hanaya K, Taguchi K, Wada Y, Kawano M.
europepmc   +3 more sources

K₂CO₃-Promoted Formal [3+3]-Cycloaddition of N-Unsubstituted Isatin N,N′-Cyclic Azomethine Imine 1,3-Dipoles with Knoevenagel Adducts

Molecules, 2023
The synthesis of dicyclic spiropyridazine oxoindole derivatives by using [3+3]-cycloaddition of N-unsubstituted isatin N,N′-cyclic azomethine imine 1,3-dipoles was reported.
Guosheng Yang, Sicheng Li, Qiumi Wang, Huabao Chen, Chunping Yang, Zhongqiong Yin, Xu Song, Li Zhang, Cuifen Lu, Guizhou Yue   +9 more
doaj   +1 more source

Exploring Regio- and Stereoselectivity in [3+2] Cycloaddition: Molecular Electron Density Theory Approach for Novel Spirooxindole-Based Benzimidazole with Pyridine Spacer

Crystals, 2023
A new ethylene derivative was synthesized as a precursor for the [3+2] cycloaddition (32CA) reaction to access a novel spirooxindole embodied with benzimidazole with a pyridine spacer.
Saeed Alshahrani, Abdullah Mohammed Al-Majid, Abdullah Saleh Alamary, Mar Ríos-Gutiérrez, Assem Barakat   +4 more
doaj   +1 more source

[Bmim]Br Accelerated One-Pot Three-Component Cascade Protocol for the Construction of Spirooxindole–Pyrrolidine Heterocyclic Hybrids

Molecules, 2020
Our synthetic approach for the assembly of structurally complex spirooxindole heterocyclic hybrids was based on an ionic liquid, [bmim]Br mediated one-pot three-component cascade reaction strategy involving 1,3-dipolar cycloaddition reaction of N-1-(2 ...
Raju Suresh Kumar, Dhaifallah M. Al-thamili, Abdulrahman I. Almansour, Natarajan Arumugam, Necmi Dege   +4 more
doaj   +1 more source