Results 41 to 50 of about 34,903 (209)

A Study on Ceftazidime/Avibactam and Aztreonam Synergy Among Aztreonam-resistant Metallo-β-lactamase Producing Enterobacterales in a Tertiary Care Hospital

Mediterranean Journal of Infection, Microbes and Antimicrobials
Introduction: Global detection of bacteria harboring metallo-β-lactamase (MBL) genes has increased at an alarming rate. However, there is no concurrent increase in available antibiotics for treatment, which has turned these infections into a public ...
Adelyn D’SOUZA, Rachana SHETTY, Asha Pai KB   +2 more
doaj   +1 more source

A treatment evaluator tool to monitor the real-world effectiveness of inhaled aztreonam lysine in cystic fibrosis [PDF]

, 2017
Background: Studies are required that evaluate real-world outcomes of inhaled aztreonam lysine in patients with cystic fibrosis (CF). Methods: Our treatment-evaluator tool assessed the effectiveness of inhaled aztreonam in routine practice in 117 CF ...
Amadori, Andrew M Jones, Assael, Barry, Barry J Plant, Bell, Britto, Cano Megías, Cedric Gunaratnam, Charles S Haworth, Cherniak, Damian G Downey, Daniel G Peckham, Davies, de Boer, Diana Bilton, Döring, Edward F McKone, Flume, Garrison, Harrison, Herland, Joe A Eustace, Kerem, Liou, McCoy, McKone, Mogayzel, National Research Ethics Service (NRES), Oermann, Plant, Quittner, R. Ian Ketchell, Retsch-Bogart, Roche, Sanders, Steinkamp   +36 more
core   +1 more source

Resistance to aztreonam-avibactam due to CTX-M-15 in the presence of penicillin-binding protein 3 with extra amino acids in Escherichia coli

Frontiers in Microbiology, 2022
Aztreonam-avibactam is a promising combination to treat carbapenem-resistant Enterobacterales including coverage for metallo-β-lactamases. Escherichia coli strains resistant to aztreonam-avibactam have emerged but resistance mechanisms remain to be ...
Ke Ma, Zhiyong Zong, Zhiyong Zong, Zhiyong Zong   +3 more
doaj   +1 more source

The Distribution of ESBL-Producing Enterobacteriaceae: Leicestershire UK Compared to Worldwide [PDF]

, 2019
open access ...
Reid, R., Samarasinghe, S., Varnakulasingam, Atheena   +2 more
core   +1 more source

Therapeutic Options for Metallo-β-Lactamase-Producing Enterobacterales [Corrigendum]

Infection and Drug Resistance, 2021
Tan X, Kim HS, Baugh K, et al. Infect Drug Resist.2021;14:125–142.  Page 134, left column, second paragraph, fourth sentence from the bottom, the text “Generally, all four tetracyclines have higher tissue concentrations than ...
Tan X, Kim HS, Baugh K, Huang Y, Kadiyala N, Wences M, Singh N, Wenzler E, Bulman ZP   +8 more
doaj  

SENTRY antimicrobial surveillance program report: latin american and brazilian results for 1997 through 2001 [PDF]

, 2004
The alarming emergence and spread of antimicrobial resistance among common bacteria threatens the effectiveness of therapy for many infections. Surveillance of antimicrobial resistance is essential to identify the major problems and guide adequate ...
Gales, Ana Cristina, Jones, Ronald N., Pignatari, Antonio Carlos Campos, Sader, Helio Silva, Silva, Juliana B.   +4 more
core   +3 more sources

Activity of cefiderocol against high-risk clones of multidrug-resistant Enterobacterales, Acinetobacter baumannii, Pseudomonas aeruginosa and Stenotrophomonas maltophilia [PDF]

, 2020
BACKGROUND: Cefiderocol is a novel siderophore cephalosporin, developed for activity against MDR Gram-negative bacilli (MDR-GNB). OBJECTIVES: To assess the in vitro antibacterial activity of cefiderocol against a collection of MDR-GNB clinical ...
Conejo, Mª del Carmen, Delgado Valverde, María Mercedes, Fernández Cuenca, Felipe Manuel, Pascual Hernández, Álvaro, Serrano, Lara   +4 more
core   +1 more source

Antimicrobial susceptibility pattern and multidrug resistance ındex in Pseudomonas aeruginosa among clinical isolates in Denizli, Turkey [PDF]

, 2018
Background: Pseudomonas aeruginosa is an important hospital infection agent causing morbidity and mortality with the ability to gain resistance to many antimicrobials. The objective of this study was to determine the sensitivity profiles of nosocomial P.
Keskin, D., Kıraç, Selma, Yarar, M.
core   +2 more sources

In vitro activity of aztreonam in combination with relebactam against gram-negative pathogens producing various serine and metallo-β-lactamases

Journal of Global Antimicrobial Resistance
Objectives: Infections caused by carbapenemase-producing Gram-negative pathogens have become a significant global public health challenge due to limited treatment options.
Kengo Hayashi, Masahiro Suzuki, Yoshikazu Ishii, Yasufumi Matsumura, Kazuaki Matsumoto, Sho Saito, Yohei Doi   +6 more
doaj   +1 more source

Structural and Functional Aspects of Class A Carbapenemases. [PDF]

, 2016
The fight against infectious diseases is probably one of the greatest public health challenges faced by our society, especially with the emergence of carbapenem-resistant gram-negatives that are in some cases pan-drug resistant.
Dortet, L, Iorga, BI, Naas, T
core   +3 more sources