Results 21 to 30 of about 23,919 (200)

Efektivitas dan Keamanan Penggunaan Aztreonam pada Pasien dengan Cystic Fibrosis : Sebuah Kajian Sistematik [PDF]

, 2022
Cystic fibrosis (CF) adalah penyakit resesif autosomal yang ditandai dengan sekresi paru yang kental, infeksi saluran napas kronis dan insufisiensi pankreas. Bakteri patogen utama penyebab CF yaitu Pseudomonas aeruginosa (Pa).
Riadi, Sahrul, Herawati, Fauna
core   +1 more source

Clinical perspective on aztreonam lysine for inhalation in patients with cystic fibrosis [PDF]

, 2010
Martha K Daddario1, Jennifer K Hagerman2, Michael E Klepser21Spectrum Health, Grand Rapids, Michigan; 2Ferris State University College of Pharmacy, Kalamazoo, Michigan, USAAbstract: Progressive obstructive lung disease is a characteristic component of ...
Jennifer K Hagerman, Jennifer Hagerman, Martha K Daddario, Michael E Klepser   +3 more
core   +1 more source

Aztreonam

Medical Clinics of North America, 1995
Aztreonam is a monocyclic beta-lactam antibiotic that is active exclusively against the aerobic gram-negative bacilli. It is not ototoxic or nephrotoxic and so is used as an alternative to aminoglycosides in a variety of clinical situations.
D H, Johnson, B A, Cunha
openaire   +2 more sources

The First Experience of Combined Use of Cefepime/Sulbactam and Aztreonam in ICU Patients with Nosocomial Infections Caused by Carbapenem-Resistant Gram-Negative Microorganisms Producing Class B and D Carbapenemases

Антибиотики и Химиотерапия, 2023
Background. The difficulties of antibacterial therapy of infections caused by carbapenemase-producing  gram-negative bacteria are associated with limited options for adequate therapy since, in addition to resistance to carbapenems and other beta-lactams ...
M. P. Suvorova, I. N. Sychev, O. V. Ignatenko, E. N. Burmistrova, S. S. Mirzakhamidova, L. V. Fedina, R. M. Vakolyuk, S. V. Yakovlev   +7 more
doaj   +1 more source

The phenomenon of changing aztreonam susceptibility in Pseudomonas aeruginosa during formation of colistin resistance in vitro [PDF]

Клиническая микробиология и антимикробная химиотерапия
Objective. To describe the phenotypic and genome characteristics of the phenomenon of aztreonam susceptibility changes in a clinical Pseudomonas aeruginosa isolate developing colistin resistance in an evolutionary experiment in vivo.
Bocharova Yu.A., Kuleshov K.V., Chebotar I.V., Mayanskiy N.A.   +3 more
doaj   +1 more source

Integron-encoded GES-type extended-spectrum ß-lactamase with increased activity toward aztreonam in Pseudomonas aeruginosa [PDF]

, 2005
A Pseudomonas aeruginosa strain expresses an extended-spectrum β-lactamase, GES-9, which differs from GES-1 by a Gly243Ser substitution, is inhibited by clavulanic acid and imipenem, and hydrolyzes aztreonam.
Fortineau, N., Nordmann, P., Brinas, L., Poirel, L. [0000-0001-5160-5286]   +3 more
core   +1 more source

Detecting KPC-2 and NDM-1 Coexpression in Klebsiella pneumoniae Complex from Human and Animal Hosts in South America

Microbiology Spectrum, 2022
Reports of Gram-negative bacteria harboring multiple carbapenemase genes have increased in South America, leading to an urgent need for appropriate microbiological diagnosis.
Felipe Vásquez-Ponce, Karine Dantas, Johana Becerra, Gregory Melocco, Fernanda Esposito, Brenda Cardoso, Larissa Rodrigues, Keila Lima, Aline V. de Lima, Fábio P. Sellera, Renata Mattos, Lucas Trevisoli, Marco A. Vianello, Thais Sincero, Jose Di Conza, Eliana Vespero, Gabriel Gutkind, Jorge Sampaio, Nilton Lincopan   +18 more
doaj   +1 more source

RNA-seq analysis shows that the aztreonam-resistant isolate D+7bld up-regulates the mexAB-oprM efflux system and attenuates response to aztreonam stress. [PDF]

, 2019
(A) We compared the transcriptomes to reference isolate D-3rsw at 0μg/mL of aztreonam and found hundreds of differentially expressed genes. (B) The up-regulation of the mexAB-oprM efflux system in D+7bld supported that the NalD mutation released the ...
Wook Kim (220700), Joao B. Xavier (169752), Henri Estanbouli (8162925), Rayees Rahman (4326538), Bernhard O. Palsson (91399), Jinyuan Yan (4326544), Weigang Qiu (4326541), Jonathan M. Monk (6732443), Chen Liao (1288563), Mini Kamboj (521791)   +9 more
core   +1 more source

Resistance to aztreonam-avibactam due to CTX-M-15 in the presence of penicillin-binding protein 3 with extra amino acids in Escherichia coli

Frontiers in Microbiology, 2022
Aztreonam-avibactam is a promising combination to treat carbapenem-resistant Enterobacterales including coverage for metallo-β-lactamases. Escherichia coli strains resistant to aztreonam-avibactam have emerged but resistance mechanisms remain to be ...
Ke Ma, Zhiyong Zong, Zhiyong Zong, Zhiyong Zong   +3 more
doaj   +1 more source

Aztreonam

Urology, 1993
Aztreonam is the first monobactam and is unique among beta-lactam antibiotics for its spectrum of activity that is exclusively active against gram-negative aerobic bacteria. Broad clinical experience with this agent supports its use in the treatment of adults with severe or complicated urologic infections.
openaire   +4 more sources