Results 31 to 40 of about 23,919 (200)

Implementation of a penicillin allergy screening tool to optimize aztreonam use [PDF]

open access: yes, 2016
PURPOSE: The implementation of a penicillin allergy screening tool to optimize the use of aztreonam is described. METHODS: This study was conducted at a 528-bed tertiary referral community teaching facility and compared the use of aztreonam in patients ...
Brundige, Mary Lourdes   +9 more
core   +1 more source

Treatment of Severe Infections Due to Metallo-Betalactamases Enterobacterales in Critically Ill Patients

open access: yesAntibiotics, 2022
Metallo-beta-lactamases-producing (MBL) Enterobacterales is a growing problem worldwide. The optimization of antibiotic therapy is challenging. The pivotal available therapeutic options are either the combination of ceftazidime/avibactam and aztreonam or
Jean-François Timsit   +2 more
doaj   +1 more source

Experimental Design Supported Liposomal Aztreonam Delivery: In Vitro Studies [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2021
Purpose: The present study focuses on a systemic approach to develop liposomal aztreonam as a promising dosage form for inhalation therapy in the treatment of pneumonia and explores the in-vitro antimicrobial and cell uptake efficacy.
Sayani Bhattacharyya   +3 more
doaj   +1 more source

Rapid Aztreonam/Avibactam NP test for detection of aztreonam/avibactam susceptibility/resistance in Enterobacterales [PDF]

open access: yes, 2023
Aztreonam-avibactam (AZA), a newly developed β-lactam/β-lactamase inhibitor combination, is a treatment option for infections due to carbapenem-resistant Enterobacterales (CRE), including metallo-ß-lactamase producers, regardless of additional production
Maxime Bouvier   +11 more
core   +1 more source

Effects of monobactam antibiotic aztreonam on platelet function and blood coagulation [PDF]

open access: yes, 1987
The effects of the new monobactam antibiotic aztreonam on platelet function and blood coagulation were evaluated both in vitro and ex vivo. In the in vitro studies carried out on platelets from 6 healthy volunteers, therapeutic concentrations of ...
Del Favero, A.   +6 more
core   +1 more source

A Study on Ceftazidime/Avibactam and Aztreonam Synergy Among Aztreonam-resistant Metallo-β-lactamase Producing Enterobacterales in a Tertiary Care Hospital

open access: yesMediterranean Journal of Infection, Microbes and Antimicrobials
Introduction: Global detection of bacteria harboring metallo-β-lactamase (MBL) genes has increased at an alarming rate. However, there is no concurrent increase in available antibiotics for treatment, which has turned these infections into a public ...
Adelyn D’SOUZA   +2 more
doaj   +1 more source

Assessment of Safety Signals for Aztreonam in Different Age Groups: National and International Drug Safety Monitoring [PDF]

open access: yes, 2022
Aztreonam is the only approved monocyclic β-lactam antibiotic for human use that is active against Gram-negative aerobes, primarily Pseudomonas аeruginosa. Aztreonam has been used for more than 35 years, and aztreonam lysine has been on the market for 15
E. A. Sokova   +5 more
core   +2 more sources

Antimicrobial Sensitivity Profile and Resistance Gene Research in Escherichia coli Isolated From Water and Fish From Lagoa da Conceição, Florianópolis, SC, Brazil

open access: yesFood Safety and Health, EarlyView.
This paper highlights a concerning scenario of environmental contamination by multidrug‐resistant bacteria, underscoring the need for integrated surveillance and control strategies to address antimicrobial resistance in aquatic environments within the context of One Health.
Francisco Lucas de Amorim Nascimento   +13 more
wiley   +1 more source

Aztreonam Lysine Increases the Activity of Phages E79 and phiKZ against Pseudomonas aeruginosa PA01

open access: yesMicroorganisms, 2021
Pseudomonas aeruginosa is a pernicious bacterial pathogen that is difficult to treat because of high levels of antibiotic resistance. A promising alternative treatment option for such bacteria is the application of bacteriophages; the correct combination
Carly M. Davis   +2 more
doaj   +1 more source

Interpretation of Key Updates in the 36th Edition of Clinical and Laboratory Standards Institute M100 Standard

open access: yesiLABMED, EarlyView.
ABSTRACT The Clinical and Laboratory Standards Institute M100 document serves as a cornerstone standard for clinical microbiology laboratories in China. Maintaining the scientific rigor of its predecessors, the 36th edition incorporates updated epidemiological cutoff values, pharmacokinetic/pharmacodynamic data, and clinical efficacy evidence to revise
Kanghong Xu, Qi Wang, Hui Wang
wiley   +1 more source

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