Results 51 to 60 of about 34,903 (209)

Decision fatigue in hospital medicine: A retrospective exploratory evaluation

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background “Decision fatigue” (DF) is the deterioration in decision‐making ability stemming from repeated decision making. Objective Explore DF over the clinical workblock and across hospitalist and work characteristics. Methods Patients seen by hospitalists at two hospitals in January and February 2022 were retrospectively evaluated for ...
Rachel M. Kruer   +6 more
wiley   +1 more source

Recent advances in the treatment of Pseudomonas aeruginosainfections in cystic fibrosis [PDF]

open access: yes, 2011
Chronic Pseudomonas aeruginosa lung infection in cystic fibrosis (CF) patients is caused by biofilm-growing mucoid strains. Biofilms can be prevented by early aggressive antibiotic prophylaxis or therapy, and they can be treated by chronic suppressive ...
Niels Høiby
core   +3 more sources

Emergence and Genomic Characterization of a Hypervirulent Klebsiella pneumoniae Isolate From a New Clone in Brazil

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT Hypervirulent Klebsiella pneumoniae (hvKp) has emerged globally as a major public health concern, often associated with severe community‐acquired and healthcare‐associated human infections. Despite alerts from PAHO/WHO on convergent hvKp strains with multidrug resistance in Latin America, comprehensive data from Brazil, the region's largest ...
Carlos Henrique Camargo   +21 more
wiley   +1 more source

Aztreonam Combinations with Avibactam, Relebactam, and Vaborbactam as Treatment for New Delhi Metallo-β-Lactamase-Producing Enterobacterales Infections—In Vitro Susceptibility Testing

open access: yesPharmaceuticals
Antimicrobial resistance is a major global health issue. Metallo-β-lactamases (MBL), in particular, are problematic because they can inactivate all classes of β-lactams except aztreonam.
Małgorzata Brauncajs   +3 more
doaj   +1 more source

Detecting KPC-2 and NDM-1 Coexpression in Klebsiella pneumoniae Complex from Human and Animal Hosts in South America

open access: yesMicrobiology Spectrum, 2022
Reports of Gram-negative bacteria harboring multiple carbapenemase genes have increased in South America, leading to an urgent need for appropriate microbiological diagnosis.
Felipe Vásquez-Ponce   +18 more
doaj   +1 more source

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) [PDF]

open access: yes, 2016
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.
A   +173 more
core   +4 more sources

Invasive Fungal Infections After Intestine Transplantation: Epidemiology and Outcomes

open access: yesMycoses, Volume 69, Issue 5, May 2026.
ABSTRACT Background Invasive fungal infections (IFIs) represent a major complication after intestine transplantation, with reported incidence rates between 40% and 49%. These infections are associated with high morbidity and allograft loss. This study evaluates the impact of post‐transplant IFIs on graft outcomes in intestine transplant recipients ...
Mayyadah H. Alabdely   +4 more
wiley   +1 more source

DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut

open access: yesAdvanced Science, Volume 13, Issue 24, 27 April 2026.
Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su   +16 more
wiley   +1 more source

Walla Walla General Hospital: Setting Staff Up for Success in Pneumonia Care [PDF]

open access: yes, 2010
Outlines education and reinforcement strategies, including building a quality culture and implementing a hospitalist program, standardized order sets, and staff supports, that enable high performance on pneumonia care core measures.
Aimee Lashbrook
core  

The 2018 Garrod Lecture: Preparing for the Black Swans of Resistance [PDF]

open access: yes, 2018
The need for governments to encourage antibiotic development is widely agreed, with ‘Market Entry Rewards’ being suggested. Unless these are to be spread widely – which is unlikely given the $1 billion sums proposed– we should be wary, for this approach ...
Livermore, David
core   +1 more source

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