Results 1 to 10 of about 16,488,690 (299)
Computational Methods to Predict Conformational B-Cell Epitopes [PDF]
BiomoleculesAccurate computational prediction of B-cell epitopes can greatly enhance biomedical research and rapidly advance efforts to develop therapeutics, monoclonal antibodies, vaccines, and immunodiagnostic reagents.
M. Carroll, E. Rosenbaum, R. Viswanathan
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An Introduction to B-Cell Epitope Mapping and In Silico Epitope Prediction [PDF]
Journal of Immunology Research, 2016 Identification of B-cell epitopes is a fundamental step for development of epitope-based vaccines, therapeutic antibodies, and diagnostic tools. Epitope-based antibodies are currently the most promising class of biopharmaceuticals. In the last decade, in-
Lenka Potocnakova +2 more
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Bcipep: A database of B-cell epitopes [PDF]
BMC Genomics, 2005 Abstract Background Bcipep is a database of experimentally determined linear B-cell epitopes of varying immunogenicity collected from literature and other publicly available databases. Results The current version of Bcipep database ...
Bhasin Manoj +2 more
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Analysis of Virus-Specific B Cell Epitopes Reveals Extensive Antigen Degradation Prior to Recognition [PDF]
CellsB cell epitopes must be visible for recognition by cognate B cells and/or antibodies. Here, we studied that premise for known linear B cell epitopes that were collected from the Immune Epitope Database as being recognized by humans during microbial ...
Alvaro Ras-Carmona, Pedro A. Reche
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Optimizing sheep B-cell epitopes in Echinococcus granulosus recombinant antigen P29 for vaccine development [PDF]
Frontiers in ImmunologyBackgroundEchinococcus granulosus is a widespread zoonotic parasitic disease, significantly impacting human health and livestock development; however, no vaccine is currently available for humans. Our preliminary studies indicate that recombinant antigen
Jihui Yang +15 more
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B–cell epitopes within swine flu virus T–cell epitopes
Asian Pacific Journal of Tropical Biomedicine, 2014 Viroj Wiwanitkit
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BepiTBR: T-B reciprocity enhances B cell epitope prediction
iScience, 2022 Summary: The ability to predict B cell epitopes is critical for biomedical research and many clinical applications. Investigators have observed the phenomenon of T-B reciprocity, in which candidate B cell epitopes with nearby CD4+ T cell epitopes have ...
James Zhu +5 more
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Frontiers in Immunology, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) kills thousands of people worldwide every day, thus necessitating rapid development of countermeasures.
Patil Pranita Uttamrao +3 more
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Improved method for linear B-cell epitope prediction using antigen's primary sequence. [PDF]
PLoS ONE, 2013 One of the major challenges in designing a peptide-based vaccine is the identification of antigenic regions in an antigen that can stimulate B-cell's response, also called B-cell epitopes.
Harinder Singh +2 more
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Prediction of B cell epitopes in proteins using a novel sequence similarity-based method
Scientific Reports, 2022 Prediction of B cell epitopes that can replace the antigen for antibody production and detection is of great interest for research and the biotech industry. Here, we developed a novel BLAST-based method to predict linear B cell epitopes.
Alvaro Ras-Carmona +3 more
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