Results 171 to 180 of about 12,336,620 (246)

Prolymphocytic Progression in Chronic Lymphocytic Leukemia Without Richter Transformation: An Eighteen-Year Clinical-Diagnostic Correlation. [PDF]

Case Rep Hematol
Ravisankar HV, Umrau K, Cheng L, Czader M, Gulati R.   +4 more
europepmc   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Optic nerve infiltration in chronic lymphocytic leukemia treated with acalabrutinib monotherapy: A case report. [PDF]

Am J Ophthalmol Case Rep
Shakarchi FF, Chacko JA, Chacko JG, Govindarajan R, Zent CS, Uwaydat SH.   +5 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, Volume 20, Issue 9, Page 2296-2322, September 2026.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Epidemiology, Presenting Features and Treatment Outcomes of Patients With Chronic Lymphocytic Leukemia (CLL) in Tanzania. [PDF]

Hematol Oncol
Saleh SS, Nasser A, Ally M, Chamba C, Ndobho F, Lyimo M, Schuh A, Mawalla WF.   +7 more
europepmc   +1 more source

Clinical Phenotypes, Treatment, and Outcomes of Rheumatic Immune–Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitors: A Rheumatologists‐Referred Multicenter German Registry Cohort

ACR Open Rheumatology, Volume 8, Issue 9, September 2026.
Objective Immune checkpoint inhibitors (ICIs) induce a broad range of immune‐related adverse events (irAEs), including rheumatic manifestations. Evidence from dedicated rheumatology cohorts on the clinical spectrum, severity, treatment, and outcomes of rheumatic irAEs (rh‐irAEs) remains limited.
Didzis Gailis, Fabian T.H. Ullrich, Sophia Dombret, Marc Schmalzing, Rebecca Hasseli‐Fräbel, Torsten Witte, Thea Thiele, Uta Kiltz, Mara Oleszowsky, Marcel Müller, Karolina Gente, Christof Specker, Matthias B. Thaler, Alla Skapenko, Hendrik Schulze‐Koops   +14 more
wiley   +1 more source

Genome‐Wide Association Study of Symptom Change Following Cognitive Behavioral Therapy for Common Mental Disorders

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 6, Page 396-405, September 2026.
ABSTRACT Cognitive behavioral therapy (CBT) is a well‐established, evidence‐based treatment for common mental disorders such as depression, anxiety disorders, and obsessive‐compulsive disorder (OCD). However, treatment outcomes vary widely, and a substantial proportion of patients do not achieve sufficient improvement.
Julia Bäckman, Olly Kravchenko, Matthew Halvorsen, Elles de Schipper, Ekaterina Ivanova, Viktor Kaldo, Nils Hentati Isacsson, Thorstein Olsen Eide, Kira D. Höffler, Manuel Mattheisen, Bjarne Hansen, Gerd Kvale, Kristen Hagen, Jan Haavik, David Mataix‐Cols, James J. Crowley, John Wallert, Christian Rück, Nordic OCD and Related Disorders Consortium (NORDiC), Julia Bäckman, Long‐Long Chen, James J. Crowley, Elles de Schipper, Diana Pascal, Jan Haavik, Kristen Hagen, Matthew W. Halvorsen, Bjarne Hansen, Kira D. Höffler, Fredrik Johansson, Anna K. Kähler, Elinor K. Karlsson, Gerd Kvale, Paul Lichtenstein, Kerstin Lindblad‐Toh, Manuel Mattheisen, David Mataix‐Cols, Kathleen Morrill, Christian Rück, Thorstein Olsen Eide, Nora I. Strom, John Wallert   +41 more
wiley   +1 more source

Acquired Amegakaryocytic Thrombocytopenia Presenting as Pancytopenia in a Patient With Chronic Lymphocytic Leukemia: A Case Report. [PDF]

Case Rep Hematol
Chen CC, Shah A, Andrawis M, Benjamin J, Shah M, Fratella-Calabrese A, Chang VT.   +6 more
europepmc   +1 more source

Acupuncture Attenuates Neuroinflammation Following Acute Cerebral Infarction by Downregulating SPP1 to Ameliorate Immunological Niches

Brain and Behavior, Volume 16, Issue 9, September 2026.
The study workflow and key mechanistic findings are illustrated. In cohort 1, serum samples from acute cerebral infarction (ACI) patients and healthy controls were screened using proteomics to identify differentially expressed proteins. In cohort 2, the therapeutic effects of acupuncture on ACI were further validated.
Jiang‐Peng Cao, Xiao‐Xi Liu, Ling‐Fei Wang, Ying Zhou, Lin Zhang, Xu‐Juan Chen, Yue‐Xin Lin, Lin‐Ling Chen, Yuan‐Hao Du   +8 more
wiley   +1 more source

Emergence of Two Rare Malignancies, Langerhans Cell Sarcoma and Myeloid Sarcoma, After Targeted Therapy for Chronic Lymphocytic Leukaemia: A Case Report. [PDF]

Cureus
Niblock A, Mannion N, Sweeney K.
europepmc   +1 more source