Results 71 to 80 of about 12,336,620 (246)

The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells [PDF]

, 2016
Interleukin (IL)-10-producing B cells (B10 cells) have emerged as important regulatory elements with immunosuppressive roles. Chronic lymphocytic leukemia (CLL) B cells also secrete IL-10 and share features of B10 cells, suggesting a possible ...
Vincent, FB, MacKay, F, Croce, CM, Saulep-Easton, D, Wei, A, Ting, SB, Quah, PS, Tam, C   +7 more
core   +1 more source

Double‐VISTA technique with connective tissue graft or acellular dermal matrix for treating multiple recessions associated with non‐carious cervical lesions: A retrospective study

Journal of Periodontology, EarlyView.
Abstract Background This retrospective study evaluated whether clinical outcomes differed between connective tissue graft (CTG) and allogeneic solvent‐dehydrated acellular dermal matrix (ADM) for treating multiple gingival recessions associated with non‐carious cervical lesions (NCCLs) using partial restoration and the double‐vestibular incision ...
Guo‐Hao Lin, Lan‐Lin Chiou, Yu‐Ting Yeh, Shayan Barootchi, Lorenzo Tavelli, Homayoun H. Zadeh, Hom‐Lay Wang   +6 more
wiley   +1 more source

Association between seropositivity for cytomegalovirus (CMV) and CD4+ cytotoxic T cells expansions in patients with B-cell Chronic Lymphocyte Leukaemia (B-CLL) and healthy controls

, 2009
B cell chronic lymphocytic leukaemia (B-CLL) is characterized by the clonal expansion of CD5+CD19+CD23+ B cells. During the course of B-CLL, the expansion of neoplastic clone is accompanied by a disbalance between CD4+/CD8+ T cells and by deficiency of T
Sereda, L., Ghirdaladze, M., Gachechiladze, N., Tevzadze, M., Lukhumaidze, M., Tsagareishvili, P., Amaglobeli, N., Tsertsvadze, T., Kardava, L., Kulikova, N., Porakishvili, N.   +10 more
core  

In‐frame variants in TP53 gene identified in adult leukemia samples are predominantly deleterious: a study of the TP53 Network of Education and Research Initiative on CLL

The Journal of Pathology, EarlyView.
Abstract The prognostic and predictive impact of TP53 variants in leukemia led to their inclusion in diagnostic and treatment guidelines, increasing the demand for rapid, reliable laboratory analysis, interpretation, and reporting. While most TP53 variants identified in tumor samples can be interpreted using data from large‐scale functional studies ...
Šárka Pavlová, Johana Gombíková, Silvia Petrezsélyová, Libor Macůrek, Marcela Ženatová, Marie Zádrapová, Anna Panovská, Eva Zapletalová, Blanca Ferrer Lores, Alicia Serrano Alcalá, Eugen Tausch, Stephan Stilgenbauer, Fanny Baran‐Marszak, Gregory Lazarian, Miguel Alcoceba, Ana Balanzategui, Lisa Bonello, Ivana Ježíšková, Martina Sopkovičová, Silvia Zibellini, Marzia Varettoni, Audrey Bidet, Helena Podgornik, Sandra Šućurović, Riccardo Moia, Mónica López‐Guerra, Mark Catherwood, Šárka Pospíšilová, Jitka Malčíková   +28 more
wiley   +1 more source

CLL sejtek ozmotikus rezisztencia és apoptózis vizsgálata

, 2016
Absztrakt Bevezetés: A krónikus lymphocytás leukémia (CLL) a leggyakoribb felnőttkori leukémia típus. Megfigyelték, hogy a betegek lymphocyta citoszkeletonja egyénenként jelentős heterogenitást mutat.
Kiss, Alexandra
core  

Evolutionary trade‐offs between beauvericin production and growth define divergent virulence strategies in Beauveria

Pest Management Science, EarlyView.
Two virulence strategies in Beauveria: a growth strategy characterized by rapid within‐host proliferation, and a toxin strategy involving antimicrobial activity and toxicity to insects Abstract BACKGROUND Pathogen virulence is often attributed to toxin production, yet toxins are metabolically costly and may not universally enhance fitness.
Shasha Hu, Lana L B de Carvalho, Ricardo A Polanczyk, Michael J Bidochka   +3 more
wiley   +1 more source

Cytotoxic CD4+ T cells in patients with B cell chronic lymphocytic leukemia kill via a perforin-mediated pathway

Haematologica, 2004
BACKGROUND AND OBJECTIVES: B-cell chronic lymphocytic leukemia (B-CLL) is a clonal expansion of CD5+B cells that accumulate due to their uncontrolled growth and resistance to apoptosis.
N Porakishvili, L Kardava, AP Jewell, K Yong, MJ Glennie, A Akbar, PM Lydyard   +6 more
doaj  

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre, Corinna Maier, Jiuhong Zha, Benjamin Engelhardt, Johannes E. Wolff, Sven Mensing   +5 more
wiley   +1 more source

Chronic Lymphocytic Leukemia Cells Are Activated and Proliferate in Response to Specific T Helper Cells

Cell Reports, 2013
There is increasing interest in the chronic lymphocytic leukemia (CLL) microenvironment and the mechanisms that may promote CLL cell survival and proliferation.
Audun Os, Simone Bürgler, Anna Parente Ribes, Ane Funderud, Dong Wang, Keith M. Thompson, Geir E. Tjønnfjord, Bjarne Bogen, Ludvig A. Munthe   +8 more
doaj   +1 more source

Disease-specific complications of chronic lymphocytic leukemia in binet stage a patients [PDF]

, 2012
Disease-specific Complications of Chronic Lymphocytic Leukemia in Binet Stage A Patients: Analysis of Immunodeficiency, Autoimmune Constellations and Infections in the CLL1-Protocol.
Kwag, Doo Young
core   +1 more source