Results 161 to 170 of about 14,119,663 (382)

The Membrane Receptor Complex Regulating Induction and Clonal Expansion of Normal Murine B Lymphocytes [PDF]

open access: yes, 2017
Induction of resting B lymphocytes results from the interaction of competent ligands or helper cells with "triggering receptors.” Subsequent clonal expansion and performance are thought to be regulated by the interaction of selective growth or maturation
Coutinho, Antonio   +5 more
core  

Publisher Correction: Rheumatological features of Whipple disease

open access: yesScientific Reports, 2021
Alice Tison   +15 more
doaj   +1 more source

Liver‐specific lncRNAs associated with liver cancers

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina   +3 more
wiley   +1 more source

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

open access: yesFEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno   +12 more
wiley   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto   +5 more
wiley   +1 more source

Ampk regulates IgD expression but not energy stress with B cell activation. [PDF]

open access: yes, 2019
Ampk is an energy gatekeeper that responds to decreases in ATP by inhibiting energy-consuming anabolic processes and promoting energy-generating catabolic processes.
Ahsan, Fasih M   +9 more
core   +1 more source

Evidence for hydrophobic region within heavy chains of mouse B lymphocyte membrane-bound IgM [PDF]

open access: green, 1979
P Vassalli   +4 more
openalex   +1 more source

Plasma microRNA Signature as Predictive Marker of Clinical Response to Therapy During Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite the availability of effective therapies for Multiple Sclerosis (MS), the unpredictable nature of disease progression and the variability in individual treatment outcomes call for reliable biomarkers. This pilot study aims to investigate the potential of plasma circulating microRNAs (miRNAs) as predictive biomarkers for ...
Fortunata Carbone   +19 more
wiley   +1 more source

Clinical observation of monoclonal fibrillary glomerulonephritis

open access: yesВестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Monoclonal gammopathy of renal significance is a condition caused by the proliferation of a clone of B-lymphocytes or plasma cells that does not reach the criteria required for the initiation of treatment for oncohematological indications, but is ...
T. A. Garkusha   +2 more
doaj   +1 more source

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