Results 231 to 240 of about 14,119,663 (382)

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Effect of RUNX1/FOXP3 axis on apoptosis of T and B lymphocytes and immunosuppression in sepsis. [PDF]

Open Med (Wars), 2023
Chao Y, Huang W, Xu Z, Li P, Gu S.
europepmc   +1 more source

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

Advanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee, Ruqiang Lu, Andrew House, Zizhao Li, Lindsey Hammond Burton, Katie Josephine Sikes, Lynn Marie Pezzanite, Drew William Koch, Kevin Michael Labus, Ben Gadomski, Jeremiah Easley, Richard Tuan Tran, Su Chin Heo   +12 more
wiley   +1 more source

Phenotypic alterations in peripheral blood B Lymphocytes of patients with Alzheimer's Disease. [PDF]

J Prev Alzheimers Dis
Wang MT, Wang YR, Zeng GH, Zeng XQ, Fei ZC, Chen J, Zhou J, Li XP, Xu ZQ, Wang YJ, Liu YH.   +10 more
europepmc   +1 more source

Molecular mechanisms insulating proliferation from genotoxic stress in B lymphocytes. [PDF]

Trends Immunol, 2023
Wright NE, Mandal M, Clark MR.
europepmc   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

The Role of Regulatory B Lymphocytes in Allergic Diseases. [PDF]

Biomedicines
Lipińska-Opałka A, Leszczyńska-Pilich M, Będzichowska A, Tomaszewska A, Rustecka A, Kalicki B.   +5 more
europepmc   +1 more source

B Lymphocyte: Activation by Insoluble Anti-Immunoglobulin: Induction of Immunoglobulin Secretion by a T Cell-Dependent Soluble Factor [PDF]

, 1979
David C. Parker, J J Fothergill, Daniel Wadsworth   +2 more
openalex   +1 more source

DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes

Nature, 2012
Ofir Hakim, W. Resch, Arito Yamane, Isaac A. Klein, Kyong-Rim Kieffer-Kwon, M. Jankovic, Thiago Y. Oliveira, Anne Bothmer, T. Voss, C. Ansarah-Sobrinho, E. Mathé, G. Liang, Jesse Cobell, H. Nakahashi, D. Robbiani, A. Nussenzweig, G. Hager, M. Nussenzweig, R. Casellas   +18 more
semanticscholar   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source