Results 261 to 270 of about 754,020 (340)

PI3K-dependent reprogramming of hexokinase isoforms controls glucose metabolism and functional responses of B lymphocytes. [PDF]

iScience
Paradoski BT, Hou S, Mejia EM, Olayinka-Adefemi F, Fowke D, Hatch GM, Saleem A, Banerji V, Hay N, Zeng H, Marshall AJ.   +10 more
europepmc   +1 more source

Bacterial lipopolysaccharide activates suppressor B lymphocytes.

, 1979
Scott Koenig, Michael K. Hoffmann
openalex   +1 more source

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin, Wanling Chen, Bo Li, Zhang Zhao, Zhonglin Yu, Xu‐Yun Zhao, Xuan Zhou, Zhien Feng, Chengzhong Lin, Wei Cao   +9 more
wiley   +1 more source

SOD1 Is an Integral Yet Insufficient Oxidizer of Hydrogen Sulfide in Trisomy 21 B Lymphocytes and Can Be Augmented by a Pleiotropic Carbon Nanozyme. [PDF]

Antioxidants (Basel)
Mouli K, Liopo AV, Suva LJ, Olson KR, McHugh EA, Tour JM, Derry PJ, Kent TA.   +7 more
europepmc   +1 more source

SURFACE MARKERS ON HUMAN B AND T LYMPHOCYTES

, 1973
Mikael Jondal, George Klein
openalex   +1 more source

Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair

Advanced Science, EarlyView.
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao, Huailong An, Cong Fan, Qingsu Lan, Hongyu Zhong, Yun Zhang, Libo Zhou, Panpan Hao   +7 more
wiley   +1 more source

A Compartmentalized Joint‐on‐chip (JoC) Model to Unravel the Contribution of Cartilage and Synovium to Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
A compartmentalized joint‐on‐chip (JoC) platform is here developed, modelling the interactions between cartilage and synovium in osteoarthritis (OA). Using independent culture and mechanical/biochemical stimulation, the JoC revealed how inflammation and mechanical damage drive mutual tissue changes.
Cecilia Palma, Shima Salehi, Michela Anna Polidoro, Matteo Moretti, Marco Rasponi, Silvia Lopa, Paola Occhetta   +6 more
wiley   +1 more source

TFEB activation hallmarks antigenic experience of B lymphocytes and directs germinal center fate decisions. [PDF]

Nat Commun
Münchhalfen M, Görg R, Haberl M, Löber J, Willenbrink J, Schwarzt L, Höltermann C, Ickes C, Hammermann L, Kus J, Chapuy B, Ballabio A, Reichardt SD, Flügel A, Engels N, Wienands J.   +15 more
europepmc   +1 more source

Integrative Omics Reveals Glutamine Catabolism‐Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading

Advanced Science, EarlyView.
This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding, Fan Tong, Mingqiu Liu, Pin Yang, Jing Zeng, Yinghua Wei, Chunlin Li, Dong Li, Cheng Chang, Yangjun Zhang, Shaoqiong Yi, Fan Hu, Wenjie Shu, Lingqiang Zhang, Chun‐Ping Cui   +14 more
wiley   +1 more source

Immune system dysregulation in the pathogenesis of non-alcoholic steatohepatitis: unveiling the critical role of T and B lymphocytes. [PDF]

Front Immunol
Cebi M, Yilmaz Y.
europepmc   +1 more source