Anti-Tumor Immunity in B Lymphocyte-Deprived Mice [PDF]
Penina Brodt, Julius Gordon
openalex +1 more source
In this study, lipid nanoparticles are tracked in vivo using DNA barcodes to determine how varying drug loadings affect their delivery behaviors in mice. A cost‐effective strategy is developed for simultaneously monitoring the biodistribution of a library of lipid nanoparticles (LNPs).
Letao Xu+5 more
wiley +1 more source
PI3K-dependent reprogramming of hexokinase isoforms controls glucose metabolism and functional responses of B lymphocytes. [PDF]
Paradoski BT+10 more
europepmc +1 more source
Poor Mixed Lymphocyte Reaction Stimulatory Capacity of Leukemic B Cells of Chronic Lymphocytic Leukemia Patients Despite the Presence of Ia Antigens [PDF]
James P. Halper+4 more
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This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah+9 more
wiley +1 more source
SOD1 Is an Integral Yet Insufficient Oxidizer of Hydrogen Sulfide in Trisomy 21 B Lymphocytes and Can Be Augmented by a Pleiotropic Carbon Nanozyme. [PDF]
Mouli K+7 more
europepmc +1 more source
Failure of lymphocyte-membrane HLA-A and -B expression in two siblings with combined immunodeficiency [PDF]
Ruud K. B. Schuurman+7 more
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Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun+9 more
wiley +1 more source
TFEB activation hallmarks antigenic experience of B lymphocytes and directs germinal center fate decisions. [PDF]
Münchhalfen M+15 more
europepmc +1 more source