Results 71 to 80 of about 14,096,305 (385)

Number of T- and B-lymphocytes and their functional activity in the blood of common carps aff ected by Aeromonosis, and in the treatment of probiotic Enteronormin

open access: yesНауковий вісник ветеринарної медицини, 2020
Fish bacterial infectious diseases are a signifi cant problem for aquaculture, often leading to massive fi sh deaths and signifi cant economic losses. For fi sh treatment often used antibacterial drugs: nitrofuran, antibiotics, feed antibiotics, as well ...
Solopova Kh., Vishchur O.
doaj   +1 more source

Correlation Between Immune Function Status and EBV DNA in Patients with Nasopharyngeal Carcinoma and Their Influence on Prognosis

open access: yesZhongliu Fangzhi Yanjiu, 2021
Objective To explore the correlation between EBV DNA load and peripheral immune cells (including lymphocyte supsets and natural killer cells) before treatment in patients with NPC, and analyze the influence of circulating immune cell supsets related to ...
WEI Xueling   +6 more
doaj   +1 more source

B Cell–attracting Chemokine 1, a Human CXC Chemokine Expressed in Lymphoid Tissues, Selectively Attracts B Lymphocytes via BLR1/CXCR5

open access: yesJournal of Experimental Medicine, 1998
Although most leukocytes, T lymphocytes in particular, respond to several different chemokines, there is virtually no information on chemokine activities and chemokine receptors in B lymphocytes.
D. Legler   +5 more
semanticscholar   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Newly produced T and B lymphocytes and T-cell receptor repertoire diversity are reduced in peripheral blood of fingolimod-treated multiple sclerosis patients [PDF]

open access: yes, 2014
Background: Fingolimod inhibits lymphocyte egress from lymphoid tissues, thus altering the composition of the peripheral lymphocyte pool of multiple sclerosis patients. Objective: The objective of this paper is to evaluate whether fingolimod determines
A.SOTTINI   +7 more
core   +1 more source

Pathogenesis-based treatments in primary Sjogren's syndrome using artificial intelligence and advanced machine learning techniques: a systematic literature review

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Big data analysis has become a common way to extract information from complex and large datasets among most scientific domains. This approach is now used to study large cohorts of patients in medicine. This work is a review of publications that have used
Nathan Foulquier   +5 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

HLA-DR expression in melanoma: from misleading therapeutic target to potential immunotherapy biomarker

open access: yesFrontiers in Immunology
Since the advent of anti-PD1 immune checkpoint inhibitor (ICI) immunotherapy, cutaneous melanoma has undergone a true revolution with prolonged survival, as available 5-year updates for progression-free survival and overall survival demonstrate a durable
Karim Amrane   +14 more
doaj   +1 more source

Receptor Activator of Nuclear Factor κB Ligand (RANKL) Protein Expression by B Lymphocytes Contributes to Ovariectomy-induced Bone Loss*

open access: yesJournal of Biological Chemistry, 2012
Background: The contribution of B lymphocytes to the bone loss caused by estrogen deficiency is unclear. Results: Deletion of the cytokine receptor activator of NFκB ligand from B lymphocytes, but not T lymphocytes, blunted bone loss in ovariectomized ...
M. Onal   +6 more
semanticscholar   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

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