Results 101 to 110 of about 4,686 (216)

Genome-based prediction of cross-protective, HLA-DR-presented epitopes as putative vaccine antigens for multiple Bordetella species

Microbiology Spectrum
Acellular pertussis vaccines protect against severe pertussis, but vaccine-induced immunity wanes over time. Prior animal studies showed that T-cell responses are integral to long-lasting immunity.
Muktha S. Natrajan, Jesse M. Hall, Michael R. Weigand, Yanhui Peng, Margaret M. Williams, Mohamed Momin, Frederick Heath Damron, Purnima Dubey, Maria Lucia Tondella, Lucia C. Pawloski   +9 more
doaj   +1 more source

ПЦР-диагностика инфекций, вызванных b. pertussis, b. parapertussis и b. bronchiseptica

Клиническая лабораторная диагностика, 2013
Эффективное лечение коклюша напрямую зависит от ранней диагностики. ПЦР является наиболее перспективным диагностическим методом. Разработан набор реагентов для ПЦР-диагностики коклюша, паракоклюша и бронхисептикоза, доведена оценка аналитических характеристик. Чувствительность составила 1 х 10 3 геномных эквивалентов (ГЭ) на 1 мл исследуемого материала
openaire   +1 more source

Pertussis in north-central and northwestern regions of Algeria

Journal of Infection in Developing Countries, 2016
Introduction: Pertussis outbreaks continue to occur in many countries despite high vaccination coverage. Under-diagnosed cases in adolescents and adults may result in increased transmission to infants, who are at risk of severe pertussis.
Nabila Benamrouche, Hassiba Tali Maamar, Malika Lazri, Sonia Hasnaoui, Abdelkarim Radoui, Ourida Lafer, Rachida Boukari, Chawki Kaddache, Zakia Arrada, Kheira Rahal   +9 more
doaj   +1 more source

Rates of transposition in Escherichia coli [PDF]

, 2013
The evolutionary role of transposable elements (TEs) is still highly controversial. Two key parameters, the transposition rate (u and w, for replicative and non-replicative transposition) and the excision rate (e) are fundamental to understanding their ...
Bourgard, C., Gordo, I., Sousa, A., Wahl, L. M.   +3 more
core   +1 more source

Differential detection of B. pertussis from B. parapertussis using a polymerase chain reaction (PCR) in presence of SYBR green1 and amplicon melting analysis

Molecular and Cellular Probes, 2004
Nucleic acid (DNA) from control stock strains of B. pertussis and B. parapertussis (B. pertussis strain # 9797 and B. parapertussis strain # 15234 from ATCC) was amplified by polymerase chain reaction (PCR) targeting pertussis toxin (PT) promotor region, in presence of SYBR green1 a dye that fluoresces on binding specifically to double stranded DNA ...
openaire   +2 more sources

The Role of the Aceullular Pertussis Vaccine and the Comeback of 'Pertussis Pete'?

Canadian Journal of Infectious Diseases, 2001
Pertussis or whooping cough is an acute infectious disease of the respiratory tract caused principally by Bordetella pertussis and less commonly by Bordetella parapertussis (1).
John M Conly, B Lynn Johnston
doaj   +1 more source

[The kit of reagents for polymerase chain reaction diagnostic of infections caused by B. pertussis, B. parapertussis and B. bronchiseptica].

Klinicheskaia laboratornaia diagnostika, 2013
The effective treatment of whooping cough directly depends of early diagnostics. The polymerase chain reaction diagnostic is the most perspective diagnostic technique. The kit of reagents is developed to diagnose whooping cough, parapertussis and bronchosepticosis with polymerase chain reaction.
M N, Praded, S B, Iatsyshina, T S, Selezneva, S V, Malinina, N V, Buriuleva, T E, Liubimova, N C, Vorob'eva   +6 more
openaire   +1 more source

Conserved Patterns of Symmetric Inversion in the Genome Evolution of Bordetella Respiratory Pathogens

mSystems, 2019
Whooping cough (pertussis), primarily caused by Bordetella pertussis, has resurged in the United States, and circulating strains exhibit considerable chromosome structural fluidity in the form of rearrangement and deletion.
Michael R. Weigand, Yanhui Peng, Dhwani Batra, Mark Burroughs, Jamie K. Davis, Kristen Knipe, Vladimir N. Loparev, Taccara Johnson, Phalasy Juieng, Lori A. Rowe, Mili Sheth, Kevin Tang, Yvette Unoarumhi, Margaret M. Williams, M. Lucia Tondella   +14 more
doaj   +1 more source

Multiplex real-time PCR assay for detection and differentiation of Bordetella pertussis and Bordetella parapertussis

Iranian Journal of Microbiology, 2014
Background and Objective: Rapid diagnosis of pertussis is important for the timely isolation of the infection source and early prevention measures among the contact persons, especially among non-vaccinated infants for whom pertussis is life- threatening.
Valentina Kolodkina, Vladimir Martinov, Andrey Babenko   +2 more
doaj  

Live attenuated B. pertussis as a single-dose nasal vaccine against whooping cough.

PLoS Pathogens, 2006
Pertussis is still among the principal causes of death worldwide, and its incidence is increasing even in countries with high vaccine coverage. Although all age groups are susceptible, it is most severe in infants too young to be protected by currently ...
Nathalie Mielcarek, Anne-Sophie Debrie, Dominique Raze, Julie Bertout, Carine Rouanet, Amena Ben Younes, Colette Creusy, Jacquelyn Engle, William E Goldman, Camille Locht   +9 more
doaj   +1 more source