Construction of Minitransposons for Constitutive and Inducible Expression of Pertussis Toxin in Bvg-Negative Bordetella-Bronchiseptica [PDF]
Appropriately detoxified pertussis toxin (PT) of Bordetella pertussis is considered to be an essential component of new-generation whooping cough vaccines, but the development of a procedure to obtain high levels of purified toxin has been and continues ...
Rohde, Manfred +3 more
core
Within-host dynamics of infection: from ecological insights to evolutionary predictions. [PDF]
O.R. is supported by a University Research Fellowship from The Royal Society.This is the final version of the article.
Graham, Andrea L, Restif, Olivier
core +2 more sources
ABSTRACT Background We evaluated the effectiveness of the influenza vaccine programme against infection among emergency hospital admissions with respiratory conditions in Northern Ireland during the 2023/2024 influenza season. Methods Using a test‐negative design, we compared the odds of vaccination between patients who tested positive (cases) and ...
Magda Bucholc +2 more
wiley +1 more source
CLINICAL CASE REPORT: PERTUSSIS INFECTION FOLLOWED BY A PARAPERTUSSIS INFECTION IN THE SAME CHILD
Whooping cough is a vaccine-preventable, acute respiratory disease caused by the gram-negative bacterium Bordetella pertussis. In recent years there has been a worldwide reccurrence of pertussis infection.
Nadia Brankova +4 more
doaj +1 more source
The Role of Bordetella Infections in Patients with Acute Exacerbation of Chronic Bronchitis [PDF]
: Background: : Acute exacerbations of chronic bronchitis (AECB) are associated with a variety of viral and bacterial infectious agents, some of which are potentially preventable by immunization. Bordetella pertussis, which causes whooping cough, has not
Bonhoeffer, J. +4 more
core
Multicenter Clinical Evaluation of the Automated Aries Bordetella Assay [PDF]
Molecular methods offer superior sensitivity and specificity and reduce testing turnaround time from days to hours for detection of Bordetella pertussis and Bordetella parapertussis In this study, we evaluated the performance of the automated PCR-based ...
Dunn, Ronald +6 more
core +1 more source
Abstract The use of polyhydroxybutyrate (PHB) bioplastics has the potential to create a circular and sustainable recycling plastic system. Here, we focus on PHB degradation and characterize the multidomain PHB hydrolyzing enzyme from the extremophile Thermanaeromonas tohohensis.
Stephen Quirk +5 more
wiley +1 more source
Bordetella Adenylate Cyclase-Hemolysin Toxins
Adenylate cyclase-hemolysin toxin is secreted and produced by three classical species of the genus Bordetella: Bordetella pertussis, B. parapertussis and B. bronchiseptica.
Nicole Guiso
doaj +1 more source
The Bordetella Secreted Regulator BspR Is Translocated into the Nucleus of Host Cells via Its N-Terminal Moiety: Evaluation of Bacterial Effector Translocation by the Escherichia coli Type III Secretion System. [PDF]
Bordetella bronchiseptica is genetically related to B. pertussis and B. parapertussis, which cause respiratory tract infections in humans. These pathogens possess a large number of virulence factors, including the type III secretion system (T3SS), which ...
Akio Abe +4 more
doaj +1 more source
ABSTRACT Background Hematopoietic stem cell transplantation (HSCT) in solid organ transplant recipients has been reported in adults. However, data on children are scarce. We report a case of an allogeneic HSCT in a 14‐year‐old girl to treat idiopathic very severe aplastic anemia (SAA). Case Presentation The girl developed end‐stage renal disease at the
Gintarė Mierkienė +4 more
wiley +1 more source

