Results 161 to 170 of about 47,090 (208)

c-JUN enhances CRISPR knockin anti-B7-H3 CAR T cell function in small cell lung cancer and thoracic SMARCA4-deficient undifferentiated tumors. [PDF]

open access: yesCell Rep Med
Balke-Want H   +25 more
europepmc   +1 more source

Modified protein selection strategy based on Escherichia coli's Hitchhiker transport and validation through selection of nanobodies targeting bovine interferon gamma. [PDF]

open access: yesSci Rep
Sirimanakul S   +13 more
europepmc   +1 more source

Research progress on immune microenvironment and biomarkers of small cell lung cancer. [PDF]

open access: yesJ Thorac Dis
Di N   +7 more
europepmc   +1 more source

Tissue immunogenicity: the role of MHC antigen and the lymphocyte costimulator B7-1

The Journal of Immunology, 1996
Abstract Pancreatic islet transplantation represents a potential treatment for insulin-dependent diabetes mellitus. One approach to circumvent the requirement for recipient immune suppression is to reduce or eliminate the immunogenicity of the donor graft prior to transplantation.
M, Coulombe   +5 more
openaire   +2 more sources

Coexpression of B7-1 and antigen blocks tolerance induction to antigen presented by resting B cells

The Journal of Immunology, 1996
Abstract To investigate a role for B cells as tolerogenic APCs in peripheral lymphoid organs, we have developed a system in which B cells from mice transgenic for the membrane-bound form of human mu-chain are transferred into nontransgenic recipients.
Yuschenkoff, Victoria Nicole   +3 more
openaire   +3 more sources

Antigenicity of human melanoma cells transfected to express the B7-1 co-stimulatory molecule (CD80) varies with the level of B7-1 expression

Cancer Immunology, Immunotherapy, 2000
The aim of this study was to compare the antigenicity of human melanoma cells molecularly modified by particle-mediated gene transfer to have transient or stable expression of the B7-1 co-stimulatory molecule (CD80). The unmodified melanoma cells (mel5, m21) had no constitutive expression of B7-1, but 22%-28% of cells had transient B7-1 expression 24 h
McCarthy, Donna O.   +4 more
openaire   +3 more sources

The role of the T cell costimulator B7-1 in autoimmunity and the induction and maintenance of tolerance to peripheral antigen

Immunity, 1994
T cell tolerance to peripheral antigens is believed to result mainly from the inability of parenchymal cells to present antigens in an immunogenic form due to the lack of expression of T cell costimulator. We found, however, that transgenic expression of the T cell costimulator B7-1 on the islets of Langerhans is not sufficient to abolish the in vivo ...
S, Guerder, J, Meyerhoff, R, Flavell
openaire   +2 more sources

Home - About - Disclaimer - Privacy