Results 141 to 150 of about 1,740,499 (263)

Tyrosine phosphorylation of components of the B-cell antigen receptors following receptor crosslinking. [PDF]

, 1991
Michael R. Gold, Linda Matsuuchi, R B Kelly, Anthony DeFranco   +3 more
openalex   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Analysis of Stereotyped B-Cell Receptor Frequencies Among Portuguese De Novo-Diagnosed Chronic Lymphocytic Leukemia Patients (PAIS Study). [PDF]

Cancers (Basel)
Alves D, Ferreira G, Caldas J, Fernandes M, Gaspar C, Alpoim M, Carvalhais I, Duarte S, Silva H, Montalvão A, Vargas F, Ribeiro T, António A, Coutinho R, Miranda F, Maia T, Gomes M, Carda J, Matos S, Jaime R, Raposo J.   +20 more
europepmc   +1 more source

Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (Pro-uPA).

, 1991
Hiroshi Kobayashi, Manfred Schmitt, Lothar Goretzki, N. Chucholowski, Juan J. Calvete, Michael D. Kramer, Wolfgang A. Günzler, F. Jänicke, H. Graeff   +8 more
openalex   +1 more source

A polymerase chain reaction study of the stability of Ig heavy-chain and T-cell receptor delta gene rearrangements between presentation and relapse of childhood B-lineage acute lymphoblastic leukemia [PDF]

, 1994
Colin G. Steward, NJ Goulden, F Katz, Deborah L. Baines, PG Martin, Kenneth Langlands, MN Potter, JM Chessells, A Oakhill   +8 more
openalex   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Autophagy Differentially Influences Toll-like Receptor 9 and B Cell-Receptor-Mediated B Cell Expansion, Expression of Major Histocompatibility Class II Proteins, and Antigenic Peptide Presentation. [PDF]

Int J Mol Sci
Peddaboina C, Iannucci J, Tobin RP, Shapiro LA, Newell Rogers MK.   +4 more
europepmc   +1 more source

Constitutive expression of IL-6 receptors and their role in the excessive B cell function in patients with systemic lupus erythematosus. [PDF]

, 1993
Hiroko Nagafuchi, Noboru Suzuki, Yutaka Mizushima, Tsuyoshi Sakane   +3 more
openalex   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Aberrant B cell receptor signaling responses in circulating double-negative 2 B cells from radiographic axial spondyloarthritis patients. [PDF]

J Transl Autoimmun
Wilbrink R, Neys SFH, Hendriks RW, Spoorenberg A, Kroese FGM, Corneth OBJ, Verstappen GMPJ.   +6 more
europepmc   +1 more source