Results 11 to 20 of about 4,351,772 (298)
Inflammatory B cells correlate with failure to checkpoint blockade in melanoma patients
OncoImmunology, 2021 The understanding of the role of B cells in patients with solid tumors remains insufficient. We found that circulating B cells produced TNFα and/or IL-6, associated with unresponsiveness and poor overall survival of melanoma patients treated with anti ...
Kaat de Jonge +10 more
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Human IgM+CD27+ B Cells: Memory B Cells or “Memory” B Cells? [PDF]
The Journal of Immunology, 2007 Abstract Memory B cells are generated in germinal centers (GC) and contribute to serological immunity by rapidly differentiating into plasma cells. Human memory B cells can be identified by the expression of CD27. These cells exhibit more rapid responses than naive (CD27−) B cells following stimulation in vitro, consistent with the ...
Stuart G. Tangye, Kim L. Good
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B-cell depletion therapy for multiple sclerosis
Immunological Medicine, 2021 Since the initial observation of increased immunoglobulin concentrations in the cerebrospinal fluid of multiple sclerosis (MS) patients in the 1940s, B cells have been considered to participate in the pathology of MS through the production of ...
Yusei Miyazaki, Masaaki Niino
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Frontiers in Immunology, 2022 Systemic Autoimmune Rheumatic Diseases (SARDs) are characterized by the production of anti-nuclear antibodies (ANAs). ANAs are also seen in healthy individuals and can be detected years before disease onset in SARD.
Rashi Gupta +23 more
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Nutrients Interaction with the Immune System [PDF]
Archives of Razi Institute, 2021 This study described the interactions of different nutritional components with the immune system. A detailed search was carried out on Google Scholar and PubMed databases to find out the relevant research studies using different keywords, such as ...
S Noor, S Piscopo, A Gasmi
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Medicines, 2020 Background: Dry age-related macular degeneration (AMD) is one of the leading causes of vision loss in older patients. The macula accumulates drusen with loss of retinal pigment epithelial cells and photoreceptors.
Jeffrey N. Weiss, Steven Levy
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New frontiers in Sjogren’s Syndrome diagnosis and treatment: a literature review [PDF]
Beyond Rheumatology, 2023 Sjogren’s syndrome an autoimmune disease involving mainly the exocrine glands, resulting in dryness of the mucous surface (especially the oral and ocular ones).
F. Pistone, I. Martelli, A. Tavoni
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Correlation of 4-1BBL+ B Cells in Tumor Draining Lymph Nodes with Pathological Characteristics of Breast Cancer [PDF]
Iranian Journal of Immunology, 2019 Background: B cells can increase the expression of granzyme B in CD8+ T cells through 4-1BBL/4-1BB interaction and promote anti-tumor immunity. Objective: To investigate the expression of 4-1BBL on B cells in the breast tumor draining lymph nodes (TDLNs)
Mohsen Arabpour +5 more
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Whatever will B cell be? [PDF]
Nature Reviews Immunology, 2015 Individual naive B cells show heterogeneity in their response to antigen-mediated activation.
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Stromal Cells Attract B‐Cell Progenitors to Promote B‐Cell–B‐Cell Contact and Maturation [PDF]
Scandinavian Journal of Immunology, 2005 AbstractThe in vitro differentiation of B‐lineage progenitors into Ig‐secreting mature B cells has classically required a co‐culture system containing lipopolysaccharide (LPS) and stromal cells. We have previously showed that B‐lineage progenitors cultured in round‐bottomed wells can mature and secrete immunoglobulin M (IgM) on par with cultures ...
Craig D. Milne +2 more
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