Results 31 to 40 of about 5,251,416 (217)

B cells and atherosclerosis [PDF]

American Journal of Physiology-Heart and Circulatory Physiology, 2017
B cells have emerged as important immune cells in cardiovascular disease. Initial studies have suggested that B cells protect against atherosclerosis development. However, subsequent studies demonstrating aggravation of atherosclerosis by B-2 cells have shed light on the subset-dependent effects of B cells.
Prasad, Srikakulapu, Coleen A, McNamara
openaire   +2 more sources

Stem Cell Ophthalmology Treatment Study (SCOTS): Bone Marrow-Derived Stem Cells in the Treatment of Age-Related Macular Degeneration

Medicines, 2020
Background: Dry age-related macular degeneration (AMD) is one of the leading causes of vision loss in older patients. The macula accumulates drusen with loss of retinal pigment epithelial cells and photoreceptors.
Jeffrey N. Weiss, Steven Levy
doaj   +1 more source

SUPERANTIGENS

Acta Agriculturae Slovenica, 1998
Superantigens are bacterial, viral, retroviral and some naturally occurring proteins that can specifically activate a large proportion of T and/or B cells.
Mojca NARAT
doaj   +1 more source

Microarray profile of B cells from Graves’ disease patients reveals biomarkers of proliferation

Endocrine Connections, 2020
B lymphocytes are the source of autoantibodies against the thyroid-stimulating hormone receptor (TSHR) in Graves’ disease (GD). Characterization of au toimmune B-cell expression profiles might enable a better understanding of GD pathogenesis.
Xuechao Jiang, Yonghui Wang, Xiaoying Li, Leqi He, Qian Yang, Wei Wang, Jun Liu, Bingbing Zha   +7 more
doaj   +1 more source

B Cells Regulate Neutrophilia during Mycobacterium tuberculosis Infection and BCG Vaccination by Modulating the Interleukin-17 Response [PDF]

, 2013
We have previously demonstrated that B cells can shape the immune response to Mycobacterium tuberculosis, including the level of neutrophil infiltration and granulomatous inflammation at the site of infection. The present study examined the mechanisms by
Porcelli, SA, Wang, Yanhua, Steven A. Porcelli, William R Jacobs, Flynn, Joanne L, Chen, Y, John Chan, Kozakiewicz, Lee, Qinglin Ou, Lee Kozakiewicz, Chan, John, Xu, J, Ou, Qinglin, Yong Chen (109188), John Chan (47914), Jacobs, WR, Flynn, JL, Ou, Q, Jacobs, William R, William R. Jacobs, Dunussi-Joannopoulos, K, Dunussi-Joannopoulos, Kyri, Steven A. Porcelli (47915), Chen, Yong, Joanne L Flynn, Xu, Jiayong, Kozakiewicz, L, Jiayong Xu (432778), Wang, Y, Joanne L. Flynn (5655565), William R. Jacobs Jr (199645), Chan, J, Lee Kozakiewicz (432777), Qinglin Ou (432779), Joanne L. Flynn, Yanhua Wang, Porcelli, Steven A, Yanhua Wang (127897), Jiayong Xu, Steven A Porcelli, Yong Chen, Kyri Dunussi-Joannopoulos, Kyri Dunussi-Joannopoulos (344714)   +42 more
core   +1 more source

Cryoglobulinemia and cryoglobulinemic vasculitis: etiological aspects and pathophysiological associations

Современная ревматология, 2020
The term cryoglobulinemia (CG) is used when detecting serum immunoglobulins that reversibly precipitate and form a gel at a temperature below 37 °C and dissolve when the temperature rises above 37 °C.
I. Yu. Golovach, Ye. D. Yegudina
doaj   +1 more source

Gene Editing of Primary Rhesus Macaque B Cells

, 2023
B cells and their progeny are the sources of highly expressed antibodies. Their high protein expression capabilities together with their abundance, easy accessibility via peripheral blood, and amenability to simple adoptive transfers have made them an ...
Nussenzweig, Michel C., Nishimura, Yoshiaki, Hartweger, Harald, Gautam, Rajeev, Yao, Kai-Hui, Martin, Malcolm A., Jankovic, Mila, Schmidt, Fabian, Escolano, Amelia   +8 more
core   +1 more source

Genomic regions associated with multiple sclerosis are active in B cells. [PDF]

, 2012
More than 50 genomic regions have now been shown to influence the risk of multiple sclerosis (MS). However, the mechanisms of action, and the cell types in which these associated variants act at the molecular level remain largely unknown.
Giulio Disanto, Berlanga-Taylor Antonio J., Giulio Disanto (125817), Gavin Giovannoni, Sandve, GK, Berlanga-Taylor, AJ, Antonio J. Berlanga-Taylor (179950), Morahan Julia M., Geir Kjetil Sandve (31750), Julia M Morahan, Dobson, R, Antonio J Berlanga-Taylor, Dobson Ruth, Julia M. Morahan, Gavin Giovannoni (125820), Antonio J. Berlanga-taylor, Sreeram V. Ramagopalan, Giovannoni Gavin, Ramagopalan Sreeram V., Morahan, JM, Ramagopalan, SV, Sandve Geir Kjetil, Geir Kjetil S, Ruth Dobson, Ruth Dobson (179953), Sreeram V. Ramagopalan (125826), Ramagopalan, Sreeram, Sreeram V Ramagopalan, Disanto Giulio, Julia M. Morahan (179952), Giovannoni, G, Geir Kjetil Sandve, Disanto, G   +32 more
core   +1 more source

Peripheral blood B cell subsets from patients with various activity of chronic sarcoidosis

Медицинская иммунология, 2020
Sarcoidosis is an inflammatory disease of unknown etiology, characterized by development of necrosis-free epithelioid cell granulomas, resulting in hyperactivation of various cells of the immune system.
N. M. Lazareva, I. V. Kudryavtsev, O. P. Baranova, M. K. Serebriakova, A. A. Bazhanov, T. P. Ses’, M. M. Ilkovich, A. A. Totolian   +7 more
doaj   +1 more source

Dynamic stimulation promotes functional tissue-like organization of a 3D human lymphoid microenvironment model in vitro

Cell Reports: Methods
Summary: This work focused on generating a three-dimensional (3D) in vitro dynamic model to study chronic lymphocytic leukemia (CLL) cell dissemination, homing, and mechanisms of therapy resistance.
Dafne Barozzi, Fiorella Scagnoli, Federica Barbaglio, Daniela Belloni, Davide Ribezzi, Silvia Farè, Valeria Berno, Riccardo Pinos, Marta Sampietro, Margherita Pauri, Barbara Vergani, Francesco Mantegazza, Paolo Ghia, Cristina Scielzo   +13 more
doaj   +1 more source