Results 51 to 60 of about 21,803,006 (294)

Yellow fever virus vaccination: an emblematic model to elucidate robust human immune responses

Human Vaccines & Immunotherapeutics, 2021
By preventing infectious diseases, vaccines contribute substantially to public health. Besides, they offer great opportunities to investigate human immune responses. This is particularly true for live-attenuated virus vaccines which cause resolving acute
Amandine Bovay, Silvia A. Fuertes Marraco, Daniel E. Speiser   +2 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Features of B cell subsets in primary Sjogren’s syndrome and systemic lupus erythematosus

Научно-практическая ревматология
Background. Lymphocyte subsets in autoimmune diseases, such as systemic lupus erythematosus (SLE) and primary Sjogren’s syndrome (pSS), have been intensively studied in recent years.
S. S. Benevolenskaya, I. V. Kudriavtsev, M. K. Serebriakova, I. N. Grigor’yeva, E. S. Kuvardin, A. I. Budkova, S. V. Koniakhin, D. B. Zammoeva, D. B. Motorin, A. Yu. Zaritskey, I. Z. Gaydukova, E. K. Gaydukova, S. V. Lapin, A. L. Maslyanskiy   +13 more
doaj   +1 more source

Conditioning murine B cells for immunoglobulin A production In vitro [PDF]

, 2012
The respiratory mucosa is continuously exposed to a myriad of pathogens and allergens that are inhaled during respiration. B cells of the immune system produce immunoglobulin A (IgA) that protects the respiratory mucosa from inhaled pathogens and ...
Goh, Wil
core  

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

B cells in autoimmunity

Proceedings of the National Academy of Sciences, 2000
Interest is reviving in the role of antibodies in autoimmunity. Over the last two decades, T cells occupied center stage for several reasons: They predominate within tissues undergoing autoimmune attack, they can transfer autoimmune disease in animal models, and diseases such as rheumatoid arthritis and insulin-dependent diabetes mellitus associate ...
N A, Mitchison, L R, Wedderburn
openaire   +3 more sources

The Function of Themis2 in B Cells [PDF]

, 2015
Thymocyte-expressed molecule involved in selection 2 (Themis2) is the second member of the Themis family. Recently, the first member of the Themis family, Themis, has been reported to be part of the TCR signalling cascade and its deletion severely ...
Hartweger, H
core  

Dengue virus activates polyreactive, natural IgG B cells after primary and secondary infection. [PDF]

, 2011
BACKGROUND: Dengue virus is transmitted by mosquitoes and has four serotypes. Cross-protection to other serotypes lasting for a few months is observed following infection with one serotype.
Low, Jenny G., Bela-Ong, D.B., Gu, F., Martin L. Hibberd, Fink, Katja, Mickey B Koh, Hibberd, Martin, L, Martin L Hibberd, Katja Fink, Ooi Eng Eong, Leo Yee Sin, Toh, Ying, Xiu, Balakrishnan, Thavamalar, Jenny G Low, Leo, Yee Sin, Balakrishnan, T., Devi, S., Toh Ying Xiu, Dennis B Bela-Ong, Marie Flamand, Flamand, M., Hibberd, Martin L., Flamand, Marie, Leo, Y.S., Flamand Marie, Devi Shamala, Bela-Ong, Dennis, B, Thavamalar Balakrishnan, Yee Sin Leo, Fink Katja, Fink, K., Hibberd, M.L., Jenny G. Low, Ying Xiu Toh, Ooi, E.E., Toh, Y.X., Gu Feng, Ooi, Eng, Eong, Leo, Yee, Sin, Koh, Mickey B., Hibberd Martin L., Bela-ong, Dennis B., Koh, Mickey, B, Eng Eong Ooi, Feng Gu, Low, J.G., Dennis B. Bela-Ong, Balakrishnan Thavamalar, Low, Jenny G, Low Jenny G., Shamala Devi, Toh, Ying Xiu, Bela-Ong, Dennis B, Low, Jenny, G, Mickey B. Koh, Koh Mickey B., Devi, Shamala, Ooi, Eng Eong, Hibberd, Martin L, Koh, M.B., Bela-Ong Dennis B., Koh, Mickey B, Gu, Feng   +62 more
core   +2 more sources

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Expressió de ZAP-70 en linfòcits B normals i síndromes limfoproliferatives B [PDF]

, 2006
[cat] La Leucèmia Limfàtica Crònica (LLC), la més freqüent de les leucèmies en el món occidental, és una malaltia produïda per la proliferació i cúmul de limfòcits B madurs, actualment incurable.
Crespo Maull, Marta
core   +3 more sources