Results 71 to 80 of about 5,251,416 (217)

Ig-like transcript 2 (ILT2) suppresses T cell function in chronic lymphocytic leukemia

OncoImmunology, 2017
Chronic lymphocytic leukemia (CLL) is associated with a profound dysregulation of the immune system. Loss of T cell function is frequently caused in cancer by sustained signaling of inhibitory receptors. Here, we analyzed the role of the novel inhibitory
Mónica Villa-Álvarez, Seila Lorenzo-Herrero, Ana P. Gonzalez-Rodriguez, Alejandro López-Soto, Angel R. Payer, Esther Gonzalez-Garcia, Leticia Huergo-Zapico, Segundo Gonzalez   +7 more
doaj   +1 more source

The role of FLT3L and BAFFin B cell development and homeostasis [PDF]

, 2009
The maintenance of homeostasis in the immune system is a complex process. The control of B cell numbers occurs at many different stages in the developmental pathway, and numerous factors are involved.
Rauch, Melanie
core   +1 more source

The regulatory capacity of B cells directs the aggressiveness of CLL

OncoImmunology, 2019
Chronic lymphocytic leukemia (CLL) is associated with abnormal T-cell responses responsible for defective anti-tumor activities. Intriguingly, CLL B cells share phenotypical characteristics with regulatory B (Breg) cells suggesting that they might ...
Audrey Mohr, Marie Cumin, Cristina Bagacean, Pierre Pochard, Christelle Le Dantec, Sophie Hillion, Yves Renaudineau, Christian Berthou, Adrian Tempescul, Hussam Saad, Jacques-Olivier Pers, Anne Bordron, Christophe Jamin   +12 more
doaj   +1 more source

Antigen specific B cells in myasthenia gravis patients

Immunological Medicine, 2020
Myasthenia gravis (MG) is a disease caused by pathogenic autoantibodies against the neuromuscular junction and is characterized by muscle weakness. Most MG patients produce antibodies against the acetylcholine receptor (AChR), but a subset of patients ...
Kazushiro Takata, Makoto Kinoshita, Hideki Mochizuki, Tatsusada Okuno   +3 more
doaj   +1 more source

Expressió de ZAP-70 en linfòcits B normals i síndromes limfoproliferatives B [PDF]

, 2006
[cat] La Leucèmia Limfàtica Crònica (LLC), la més freqüent de les leucèmies en el món occidental, és una malaltia produïda per la proliferació i cúmul de limfòcits B madurs, actualment incurable.
Crespo Maull, Marta
core  

Correction: The Endocytic Adaptor Eps15 Controls Marginal Zone B Cell Numbers. [PDF]

, 2013
Eps15 is an endocytic adaptor protein involved in clathrin and non-clathrin mediated endocytosis. In Caenorhabditis elegans and Drosophila melanogaster lack of Eps15 leads to defects in synaptic vesicle recycling and synapse formation. We generated Eps15-
Eckhard Wolf, Pier Paolo Di Fiore, Treise, Irina, Helmut Fuchs, Offenhäuser, Nina, Simona Ronzoni, Thure Adler, Irina Treise, Betsholtz, Christer, Di Fiore, Pier Paolo, Busch, Dirk H., Martin Hrabě de Angelis, Lucano, Caterina, Amodio, Stefania, Adler, Thure, Caterina Lucano, Nina Offenhäuser, Betsholtz, Ingrid Holmberg, Rathkolb, Birgit, Pozzi, Benedetta, Daniela Castelletti, Castelletti, Daniela, Dirk H. Busch, Anna Sciullo, Ingrid Holmberg Betsholtz, Ronzoni, Simona, Christer Betsholtz, Stefano Casola, Birgit Rathkolb, Benedetta Pozzi, Sciullo, Anna, Fuchs, Helmut, Wolf, Eckhard, Gailus-Durner, Valérie, Hrabé de Angelis, Martin, Valérie Gailus-Durner, Casola, Stefano, Stefania Amodio   +37 more
core   +1 more source

Characterization of B1-cells during experimental leukomogenesis

Вопросы вирусологии, 2020
Background. Bovine leukemia causes a significant polyclonal expansion of CD5+ , IgM+ B lymphocytes, known as persistent lymphocytosis (PL), in approximately 30% of infected cattle.
I. Yu. Ezdakova, O. V. Kapustina, M. I. Gulyukin, T. V. Stepanova   +3 more
doaj   +1 more source

Covid-19 in a patient with ANCA-associated systemic vasculitis, receiving anti-B cell therapy (rituximab)

Научно-практическая ревматология, 2020
Despite numerous publications on COVID-19, at present, conceptual thinking of the problem is only at a nascence stage. Treatment of patients with ANCA-associated systemic vasculitis (AAV) during the COVID-19 pandemic is one of the relevant issues ...
T. V. Beketova, L. M. Blank, A. M. Lila
doaj   +1 more source

The Function of Themis2 in B Cells

, 2015
Thymocyte-expressed molecule involved in selection 2 (Themis2) is the second member of the Themis family. Recently, the first member of the Themis family, Themis, has been reported to be part of the TCR signalling cascade and its deletion severely ...
Hartweger, H
core  

B cells and immunoglobulin in ABO-incompatible renal transplant patients receiving rituximab and double filtration plasmapheresis

, 2017
Background/ Purpose: The effect of rituximab on B cell and immunoglobulin production after therapeutic apheresis has not been studied in ABO-incompatible renal transplant patients.
Tsai, Meng-Kun;Wu, Ming-Shiou;Yang, Ching-Yao;Lee, Chih-Yuan;Yeh, Chi-Chuan;Hu, Rey-Heng;Lee, Po-Huang;Lai, Hong-Shiee, 胡瑞恒;吳明修;李志元;葉啟娟;楊卿堯;賴鴻緒;李伯皇;蔡孟昆   +1 more
core   +1 more source