Results 81 to 90 of about 5,251,416 (217)

B-cell Tolerance

open access: yesTransplantation, 2006
Autoreactive B cells are actively tolerized to more abundant self-antigens by a series of checkpoints involving receptor editing, deletion, anergy and competition for growth factors. In contrast, B cells reactive against rare, sequestered or tissue specific self-antigens remain functionally naïve.
Ferry, H   +6 more
openaire   +3 more sources

Conditioning murine B cells for immunoglobulin A production In vitro

open access: yes, 2012
The respiratory mucosa is continuously exposed to a myriad of pathogens and allergens that are inhaled during respiration. B cells of the immune system produce immunoglobulin A (IgA) that protects the respiratory mucosa from inhaled pathogens and ...
Goh, Wil
core  

IgM-producing tumors in the BALB/c mouse: a model for B-cell maturation [PDF]

open access: yes, 1974
Five adjuvant induced BALB/c tumors producing IgM—McPc 1748, W 3469, TEPC 183, McPc 774, and Y 5781—were characterized morphologically by electron microscopy, analysis of the distribution of surface-bound and intracytoplasmic IgM using immunofluorescence,
Citronbaum, R.   +15 more
core  

The role of ICOS in the development of CD4 T cell help and the reactivation of memory T cells [PDF]

open access: yes, 2007
We have addressed the role of the inducible costimulator (ICOS) in the development of T cell help for B cells and in the generation, survival and reactivation of memory CD4 T cells and B cells.
MacDonald, Andrew   +18 more
core   +1 more source

Allergen-specific IgG as a mediator of allergy inhibition: Lessons from mother to child

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Allergen-specific IgG produced by immune mothers is associated with less predisposition to allergy development in their children. This finding has been described by several groups over the last few decades, but the mechanisms by which maternal IgG can ...
Jefferson Russo Victor
doaj   +1 more source

A B-1a cell subset induces Foxp3(-) T cells with regulatory activity through an IL-10-independent pathway

open access: yes, 2017
Regulatory T (Treg) cells play a critical role in the maintenance of tolerance. B-1a cells belong to a specific and functionally important B-cell subset that exerts its regulatory role through the production of IL-10. While IL-10 has been correlated with
Hsu, Ling-Hui;Li, Kun-Po;Chu, Kuan-Hua;Chiang, Bor-Luen   +1 more
core   +1 more source

OEK-Based Dynamic Discrimination of B-lymphocyte Cells from Red Blood Cells

open access: yes, 2012
Exploring the clinicopathological characteristics of B-lymphocyte cells from human lymphoma patients is essential for cancer treatment. However, there are many red blood cells (RBCs) contained in the preparation sample of the B-lymphocyte cells.
Liu B(刘斌)   +4 more
core  

Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection

open access: yes, 2002
Deletion, anergy, and a spectrum of functional impairments can affect virus-specific CD8 cells in chronic viral infections. Here we characterize a low frequency population of CD8 cells present in chronic hepatitis B virus (HBV) infection which survive in
Ogg, GS   +29 more
core   +1 more source

Cytokine Contents in Chronic Lymphocytic Leukemia: Association with ZAP70 Expression

open access: yesTurkish Journal of Hematology, 2016
Objective: Chronic lymphocytic leukemia (CLL) is a disease that shows varying clinical progression, and expression of the protein tyrosine kinase ZAP70 has been described as a very valuable prognostic factor.
Nilgün Işıksaçan   +4 more
doaj   +1 more source

Alterations in Peripheral B Cell Subsets Correlate with the Disease Severity of Human Glaucoma

open access: yesJournal of Inflammation Research, 2021
Ling Yu,1,* Yang Chen,2,* Xiang Xu,2 Qiwei Dong,2,3 Wenbo Xiu,2 Qinyuan Chen,2 Jinxia Wang,2 Chong He,2,3 Jian Ye,1 Fang Lu2,3 1Department of Ophthalmology, Daping Hospital, Army Medical Center, Army Medical University, Chongqing, People’s ...
Yu L   +9 more
doaj  

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